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Estimating risk factors for spontaneous preterm delivery in teen pregnancies

  • Maternal-Fetal Medicine
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Purpose

Our aim was to estimate the perinatal risk factors associated with spontaneous preterm birth in the teenage parturient.

Methods

In a cohort study of all nulliparous teen (≤18-year old) deliveries over a 4-year period at one institution, we identified all cases of spontaneous preterm birth as defined by non-indicated delivery prior to 37 weeks of gestation. Analysis was performed using Fisher’s exact, Student t test and logistic regression modeling.

Results

Of the 650 included teen deliveries, 88 (14 %) cases of spontaneous preterm birth were identified. Teenage mothers with spontaneous preterm birth had a significantly lower body mass index (BMI) (27.2 ± 6.4 vs. 31.0 ± 6.2, p = 0.0001) and had lower gestational weight gain (14.4 ± 6.6 vs. 11.2 ± 5.0 kg, p = 0.0001) than those mothers with uncomplicated term births. In fact, a normal prepregnancy BMI (<25 kg/m2) placed the teen at elevated risk for spontaneous preterm birth (OR 3.35, 95 % CI 1.98–5.64), while prepregnancy obesity (30–35 kg/m2) was protective (OR 0.26, 95 % CI 0.12–0.58). Controlling for potential confounders such as race, tobacco or illicit drug use, late prenatal care and sexually transmitted infections did not attenuate the above findings.

Conclusions

Higher prepregnancy BMI, especially obesity, appears to be protective against spontaneous preterm birth in the nulliparous teen parturient. Further studies confirming this finding and investigation of potential underlying mechanisms of this association are warranted.

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Acknowledgments

The resources of the BHRC research network are gratefully acknowledged.

Conflict of interest

We declare that we have no conflict of interest to disclose.

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Authors and Affiliations

  1. Memorial Health University Medical Center, Mercer School of Medicine, Savannah Campus, 4750 Waters Avenue, Suite 302, Savannah, GA, 31404, USA

    Arthur M. Baker

  2. St. David’s Women’s Center of Texas, North Austin Maternal-Fetal Medicine, Austin, TX, USA

    Sina Haeri

Authors
  1. Arthur M. Baker
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  2. Sina Haeri
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Corresponding author

Correspondence to Arthur M. Baker.

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Baker, A.M., Haeri, S. Estimating risk factors for spontaneous preterm delivery in teen pregnancies. Arch Gynecol Obstet 289, 1203–1206 (2014). https://doi.org/10.1007/s00404-014-3149-0

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  • DOI: https://doi.org/10.1007/s00404-014-3149-0

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