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Peritoneal tuberculosis in premenopausal patients with elevated serum CA 125

  • General Gynecology
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Introduction

Peritoneal tuberculosis predominantly involves the omentum, intestinal tract, liver, spleen, and genitourinary tract and occurs in 1–4% of patients with pulmonary tuberculosis. Peritoneal tuberculosis may mimic a pelvic mass in imaging studies and also may increase CA-125 levels. Peritoneal tuberculosis may also produce massive ascites, and intraperitoneal gross appearance might be similar to the peritoneal carcinomatosis. Therefore, peritoneal tuberculosis is often confused with advanced-stage epithelial carcinoma because of similar clinical, radiologic, and laboratory findings and later intraoperative findings.

Materials and methods

The pathology records between January 2000 and August 2008 were retrospectively reviewed at 19 Mayis University Hospital. Twenty-two patients were found to have peritoneal caseating necrosis. A total of 13 out of 22 patients were found to have high CA 125 level.

Results

Among these 13 patients, 8 patients received/are receiving anti-tuberculous therapy after they were incidentally diagnosed with peritoneal tuberculosis.

Conclusion

Increased CA 125 levels should be evaluated carefully prior to aggressive surgical approach, especially in premenopausal women and frozen section evaluation should be done before extensive surgical procedure if there is any suspicion.

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Conflict of interest statement

There is no conflict of interest to disclose.

Author information

Authors and Affiliations

  1. Department of General Surgery, 19 Mayis University Medical Faculty, Samsun, Turkey

    Ali Naki Ulusoy, Ilhan Karabicak & Kadir Dicle

  2. Department of Pathology, 19 Mayis University Medical Faculty, Samsun, Turkey

    Mehmet Kefeli

  3. Department of Obstetrics and Gynaecology, 19 Mayis University Medical Faculty, Samsun, Turkey

    Migraci Tosun, Mehmet Cetinkaya, Tayfun Alper & Cazip Ustun

  4. 2415 Brigham St, #1, Brooklyn, NY, 11235, USA

    Ilhan Karabicak

Authors
  1. Ali Naki Ulusoy
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  2. Ilhan Karabicak
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  3. Kadir Dicle
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  4. Mehmet Kefeli
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  5. Migraci Tosun
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  6. Mehmet Cetinkaya
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  7. Tayfun Alper
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  8. Cazip Ustun
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Correspondence to Ilhan Karabicak.

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Ulusoy, A.N., Karabicak, I., Dicle, K. et al. Peritoneal tuberculosis in premenopausal patients with elevated serum CA 125. Arch Gynecol Obstet 282, 639–642 (2010). https://doi.org/10.1007/s00404-009-1283-x

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  • DOI: https://doi.org/10.1007/s00404-009-1283-x

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