Abstract
Objective
To investigate the performance of an open MRI system at its conceptual limits by examining excessively obese patients who otherwise could not receive adequate imaging examinations.
Methods
Twenty-six excessively obese patients (BMI ≥ 35, average age 46) where CT, standard MR or ultrasound examinations were not possible or not conclusive were referred to an open MRI system at 1.0 Tesla. Image quality was measured by SNR and CNR with the integrated body coil for obese patients and optimal body coils for a regular weight control group (average BMI 23, average age 30). MRI findings were evaluated by a diagnostic impact matrix.
Results
SNR and CNR were generally lower in obese patients when the integrated body coil was used compared to the normal weight group with ideal body coils e.g.: For cerebral imaging T2W TSE (<5% for white matter, ca. 30% for grey matter) and T1W SE (ca. 15% for white matter, <5% for grey matter), for spinal imaging T2W TSE (ca. 35% for disc and vertebral body) and T1W SE (about 2% for disc, ca. 10% for vertebral body). Relevant new diagnoses impacting patient’s therapy were identified in 30% (8/26), the particular medical question of the referring physician could be ruled out as possible reason for the medical condition in 53% (14/26).
Conclusion
In excessively obese patients where CT, standard MR or ultrasound examination is not possible or not conlusive open MRI system have great potential in diagnostic evaluation, offering lower but sufficient image quality to impact therapy.
Similar content being viewed by others
References
Fried M, Hainer V, Basdevant A et al (2007) Inter-disciplinary European guidelines on surgery of severe obesity. Int J Obes 31:569–77
Chinnaiyan KM, McCullough PA, Flohr TG et al (2008) Improved noninvasive coronary angiography in morbidly obese patients with dual-source computed tomography. J Cardiovasc Comput Tomogr 3:35–42
World Health Organization (1995) Physical status: the use and interpretation of anthropometry, Report of a WHO Expert Committee. WHO technical report series, vol 854. World Health Organization, Geneva, p 452
Buckley O, Ward E, Ryan A et al (2009) European obesity and the radiology department. What can we do to help? Eur Radiol 19:298–309
Rothschild PA, Domesek JM, Eastham ME et al (1991) MR imaging of excessively obese patients: the use of an open permanent magnet. Magn Reson Imaging 9:151–4
Yanch JC, Behrman RH, Hendricks MJ et al (2009) Increased radiation dose to overweight and obese patients from radiographic examinations. Radiology 252:128–39
Donnelly LF, O’Brien KJ, Dardzinski BJ et al (2003) Using a phantom to compare MR techniques for determining the ratio of intraabdominal to subcutaneous adipose tissue. AJR Am J Roentgenol 180:993–8
Gomi T, Kawawa Y, Nagamoto M et al (2005) Measurement of visceral fat/subcutaneous fat ratio by 0.3 tesla MRI. Radiat Med 23:584–7
World Health Organization (2000) Obesity: preventing and managing the global epidemic, Report of a WHO consultation. WHO technical report series, vol 894. World Health Organization, Geneva, p 253
World Health Organization (2010) BMI classification. World Health Organization, Geneva. Available at http://apps.who.int/bmi/index.jsp?introPage=intro_3.html. Accessed 25 Mar 2010
Nitz WR (1999) MR imaging: acronyms and clinical applications. Eur Radiol 9:979–97
Nitz WR (2003) Magnetic resonance imaging. Sequence acronyms and other abbreviations in MR imaging. Radiologe 43:745–63
Adams JP, Murphy PG (2000) Obesity in anaesthesia and intensive care. Br J Anaesth 85:91–108
Burns J, Erdfarb A, Schneider J et al (2009) Pediatric Lumbar Disc Disease: MRI abnormalities in normal and overweight children. Session: Pediatric. Radiological Society of North America scientific assembly and annual meeting program. Oak Brook, Ill. Radiological Society of North America, pp 1054–1055
An Introduction to the Obesity Epidemic (2009) Session: obesity: a challenge for ultrasound imaging (abstr.). In: Radiological Society of North America scientific assembly and annual meeting program. Oak Brook, Ill: Radiological Society of North America, p 236
Uppot R (2009) Obesity and imaging: its implications for US. Session: the metabolic syndrome and its impact on US (abstr.). In: Radiological Society of North America scientific assembly and annual meeting program. Oak Brook, Ill: Radiological Society of North America, p 236
Wilson S (2009) The metabolic syndrome: obesity and the liver? Or, does obesity cause liver cancer? Session: the metabolic syndrome and its impact on US (abstr.). In: Radiological Society of North America scientific assembly and annual meeting program. Oak Brook, Ill: Radiological Society of North America, p 236
Glanc P (2009) Obesity and US: A perspective during pregnancy. session: the metabolic syndrome and its impact on US (abstr.) In: Radiological Society of North America scientific assembly and annual meeting program. Oak Brook, Ill: Radiological Society of North America, p 236
Barness LA, Opitz JM, Gilbert-Barness E (2007) Obesity: genetic, molecular, and environmental aspects. Am J Med Genet A 143A:3016–34
Haslam DW, James WPT (2005) Obesity. Lancet 366:1197–209
Haslam D (2007) Obesity: a medical history. Obes Rev 8:31–6
Manson JE, Willett WC, Stampfer MJ et al (1995) Body weight and mortality among women. N Engl J Med 333:677–85
Mokdad AH, Marks JS, Stroup DF et al (2004) Actual causes of death in the United States, 2000. JAMA 291:1238–45
Peeters A, Barendregt JJ, Willekens F et al (2003) Obesity in adulthood and its consequences for life expectancy: a life-table analysis. Ann Intern Med 138:24–32
Simpson D (2004) Storing up problems: the medical case for a slimmer nation. Clin Med 4:381
Sturm R (2007) Increases in morbid obesity in the USA: 2000–2005. Public Health 121:492–6
Tsai AG, Williamson DF, Glick HA (2010) Direct medical cost of overweight and obesity in the USA: a quantitative systematic review. Obes Rev. doi:10.1111/j.1467-789X.2009.00708.x
van Baal PHM, Polder JJ, de Wit GA et al (2008) Lifetime medical costs of obesity: prevention no cure for increasing health expenditure. PLoS Med 5:e29
Yach D, Stuckler D, Brownell KD (2006) Epidemiologic and economic consequences of the global epidemics of obesity and diabetes. Nat Med 12:62–6
Bales CW, Buhr GT (2009) Body mass trajectory, energy balance, and weight loss as determinants of health and mortality in older adults. Obes Facts 2:171–8
Oreopoulos A, Padwal R, Kalantar-Zadeh K et al (2008) Body mass index and mortality in heart failure: a meta-analysis. Am Heart J 156:13–22
Romero-Corral A, Montori VM, Somers VK et al (2006) Association of bodyweight with total mortality and with cardiovascular events in coronary artery disease: a systematic review of cohort studies. Lancet 368:666–78
Bray GA (2004) Medical consequences of obesity. J Clin Endocrinol Metab 89:2583–9
Calle EE, Rodriguez C, Walker-Thurmond K et al (2003) Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med 348:1625–38
Falagas ME, Kompoti M (2006) Obesity and infection. Lancet Infect Dis 6:438–46
Yosipovitch G, DeVore A, Dawn A (2007) Obesity and the skin: skin physiology and skin manifestations of obesity. J Am Acad Dermatol 56:901–16, quiz 917–20
Ejerblad E, Fored CM, Lindblad P et al (2006) Obesity and risk for chronic renal failure. J Am Soc Nephrol 17:1695–702
Anand G, Katz PO (2008) Gastroesophageal reflux disease and obesity. Rev Gastroenterol Disord 8:233–9
Whitlock G, Lewington S, Sherliker P et al (2009) Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies. Lancet 373:1083–96
Calle EE, Thun MJ, Petrelli JM et al (1999) Body-mass index and mortality in a prospective cohort of U.S. adults. N Engl J Med 341:1097–105
Freedman DM, Ron E, Ballard-Barbash R et al (2006) Body mass index and all-cause mortality in a nationwide US cohort. Int J Obes 30:822–9
Halpern BS, Dahlbom M, Auerbach MA et al (2005) Optimizing imaging protocols for overweight and obese patients: a lutetium orthosilicate PET/CT study. J Nucl Med 46:603–7
Leschka S, Stinn B, Schmid F et al (2009) Dual source CT coronary angiography in severely obese patients: trading off temporal resolution and image noise. Invest Radiol 44:720–7
Salat DH, Lee SY, van der Kouwe AJ et al (2009) Age-associated alterations in cortical gray and white matter signal intensity and gray to white matter contrast. Neuroimage 48:21–8
Acknowledgements
This study was supported by the TSB Technologiestiftung Berlin—Zukunftsfonds Berlin, Berlin, Germany, and the European Union—European Fund for Regional Development, Berlin, Germany. We grant for full disclosure of any potential relationship with industry, and all of us have nothing to disclose in relation.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
de Bucourt, M., Streitparth, F., Wonneberger, U. et al. Obese patients in an open MRI at 1.0 Tesla: image quality, diagnostic impact and feasibility. Eur Radiol 21, 1004–1015 (2011). https://doi.org/10.1007/s00330-010-2005-2
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00330-010-2005-2