Skip to main content
Log in

Focal osteolysis in total hip replacement: CT findings

  • Article
  • Published:
Skeletal Radiology Aims and scope Submit manuscript

Abstract

Objective

To describe the CT findings of focal osteolysis following total hip replacement (THR).

Design and patients

CT imaging features of 30 THRs with focal osteolysis visualized on follow-up radiographs and undertaken revision surgery were reviewed. On CT scans, the shape and anatomic location of osteolytic lesions was recorded, as well as their size and number. The presence of cortical disruption or expansion, liner wear, metallosis, and heterotopic ossification was also noted. In each case, surgical and histologic findings were correlated with imaging features.

Results

Focal osteolysis was common in the superior part of acetabular and femoral components. CT features of focal osteolysis were multiple, expansile, oval, or round radiolucencies, which were conglomerated into multilobular shape. The cortex adjacent to the osteolytic lesions revealed irregular thinning and discontinuity (29/30, 97%) accompanied by a few tiny fragments. Liner wear was common (27/30, 90%), and metallosis was frequent (8/30, 26.7%). Pathologic results were foreign body reaction in 20 patients, chronic inflammation in eight, and fibrosis in two.

Conclusion

CT appearances of focal osteolysis following THR are multilobulated lucent areas with expansile periosteal reaction and cortical abnormalities, mimicking infection or tumor. We consider that CT is useful for the prediction and assessment of the nature and extent of focal osteolysis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1A–D.
Fig. 2A–C.
Fig. 3A–C.
Fig. 4A, B.
Fig. 5A–D.

Similar content being viewed by others

References

  1. Keogh CF, Munk PL, Gee R, Chan LP, Marchinkow LO. Imaging of the painful hip arthroplasty. AJR Am J Roentgenol 2003; 180:115–120.

    PubMed  Google Scholar 

  2. Cyteval C, Hamm V, Sarrabère MP, Lopez FM, Maury P, Taourel P. Painful infection at the site of hip prosthesis: CT imaging. Radiology 2002; 224(2):477–483.

    Google Scholar 

  3. Griffiths HJ, Priest DR, Kushner D. Total hip replacement and other orthopedic hip procedures. Radiol Clin North Am 1995; 33:267–287.

    CAS  PubMed  Google Scholar 

  4. Manaster BJ. Total hip arthroplasty: radiographic evaluation. RadioGraphics 1996; 16:645–660.

    CAS  PubMed  Google Scholar 

  5. Tigges S, Stiles RG, Roberson JR. Complications of hip arthroplasty causing periprosthetic radiolucency on plain radiographs. AJR Am J Roentgenol 1994; 162:1387–1391.

    CAS  PubMed  Google Scholar 

  6. Reinus WR, Merkel KC, Gilden JJ, Berger KL. Evaluation of femoral prosthetic loosening using CT imaging. AJR Am J Roentgenol 1996; 166:1439–1442.

    CAS  PubMed  Google Scholar 

  7. White LM, Kim JK, Mehta M, et al. Complications of total hip arthroplasty: MR Imaging– initial experience. Radiology 2000; 215:254–262.

    CAS  PubMed  Google Scholar 

  8. Harris WH, Schiller AL, Scholler JM, Freiberg RA, Scott R. Extensive localized bone resorption in the femur following total hip replacement. J Bone Joint Surg Am 1976; 58:612–618.

    CAS  PubMed  Google Scholar 

  9. Santavirta S, Konttinen YT, Bergroth V, Eskola A, Tallroth K, Lindholm S. Aggressive granulomatous lesions associated with hip arthroplasty. J Bone Joint Surg Am 1990; 72:252-258.

    CAS  PubMed  Google Scholar 

  10. Schmalzried TP, Jasty M, Harris WH. Periprosthetic bone loss in total hip arthroplasty. J Bone Joint Surg Am 1992; 74:849–863.

    CAS  PubMed  Google Scholar 

  11. Hisatome T, Yasunaga Y, Ikuta Y, Takahashi K. Hidden intrapelvic granulomatous lesions associated with total hip arthroplasty: a report of two cases. J Bone Joint Surg Am 2003; 85(4):708–710.

    Google Scholar 

  12. Reinus WR, Gilula LA, Kyriakos M, Kuhlman RE. Histiocytic reaction of hip arthroplasty. Radiology 1985; 155:315–318.

    CAS  PubMed  Google Scholar 

  13. Bell RS, Ha’eri GB, Goodman SB, Fornasier VL. Case report 246. Osteolysis of the ilium associated with a loose acetabular cup following total hip arthroplasty, secondary to foreign body reaction to polyethylene and methyl methacrylate. 1983; 10:201–204.

  14. Scott WW, Riley LH, Dorfman HD. Focal lytic lesions associated with femoral stem loosening in total hip prosthesis. AJR Am J Roentgenol 1985; 144:977–982.

    PubMed  Google Scholar 

  15. Chew FS, Lev MH. Polyethylene osteolysis. AJR Am J Roentgenol 1992; 159:1254.

    CAS  PubMed  Google Scholar 

  16. Griffiths HJ, Burke J, Bonfiglio TA. Granulomatous pseudotumors in total joint replacement. Skeletal Radiol 1987; 16:146-152.

    CAS  PubMed  Google Scholar 

  17. Svensson O, Mathiesen EB, Reinholt FP, Blomgren G. Formation of a fulminant soft-tissue pseudotumor after uncemented hip arthroplasty. J Bone Joint Surg Am 1988; 70:1238–1242.

    CAS  PubMed  Google Scholar 

  18. Tigges S, Roberson JR, Cohen DE. Hip arthroplasty: the role of plain radiographs in outpatient management. Radiology 1995; 194:73–75.

    CAS  PubMed  Google Scholar 

  19. Tigges S, Stiles RG, Roberson JR. Appearance of septic hip prostheses on plain radiographs. AJR Am J Roentgenol 1994; 163:377–380.

    CAS  Google Scholar 

  20. Gruen TA, McNeice GM, Amstutx HC. “Modes of failure” of cemented stem-type femoral components. A radiographic analysis of loosening, Clin Orthop 1979; 141:17–27.

    PubMed  Google Scholar 

  21. Harris WH. Total hip replacement in the middle-aged patient: contemporary cementing for fixation of the femoral component. Orthop Clin North Am 1993; 24:611–616.

    CAS  PubMed  Google Scholar 

  22. Jones LC, Hungerford DS. Cement disease. Clin Orthop 1987; 225:192–206.

    PubMed  Google Scholar 

  23. Lassus J, Waris V, Xu JW, et al. Increased interleukin-8 (IL-8) expression is related to aseptic loosening of total hip replacement. Arch Orthop Trauma Surg 2000; 120(5–6):328-332.

    Google Scholar 

  24. Tanzer M, Maloney WJ, Jasty M, Harris W. The progression of femoral cortical osteolysis in association with total hip arthroplasty without cement. J Bone Joint Surg Am 1992; 74:404–410.

    CAS  PubMed  Google Scholar 

  25. Link TM, Berning W, Scherf S, et al. CT of metal implants: reduction of artifacts using an extended CT scale technique. J Comput Assist Tomogr 2000; 24(1):165-172.

    Google Scholar 

  26. Penman HG, Ring PA. Osteosarcoma in association with total hip replacement. J Bone Joint Surg Br 1984; 66:632–634.

    CAS  PubMed  Google Scholar 

  27. Swann M. Malignant soft-tissue tumor at the site of a total hip replacement. J Bone Joint Surg Br 1984; 66:629–631

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Kyung Nam Ryu.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Park, J.S., Ryu, K.N., Hong, H.P. et al. Focal osteolysis in total hip replacement: CT findings. Skeletal Radiol 33, 632–640 (2004). https://doi.org/10.1007/s00256-004-0812-8

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00256-004-0812-8

Keywords

Navigation