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Hippocampal sclerosis in children younger than 2 years

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Abstract

Background

Hippocampal sclerosis (HS) is rarely considered as a diagnosis in children younger than 2 years.

Objective

To describe imaging features in conjunction with clinical information in patients with hippocampal sclerosis who are younger than 2 years.

Materials and methods

We retrospectively reviewed MR brain imaging and clinical information in five children in whom the diagnosis of HS was made both clinically and by MRI prior to 2 years of age.

Results

Imaging features establishing the diagnosis of hippocampal sclerosis were bright T2 signal and volume loss, while the internal architecture of the hippocampal formation was preserved in almost all children. Clinically, all children had an infectious trigger.

Conclusion

It is necessary for radiologists to consider HS in children with certain clinical features to plan an MRI protocol that is appropriate for detection of hippocampal pathology.

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Authors and Affiliations

  1. Department of Diagnostic Imaging and Radiology, Children’s National Medical Center, 111 Michigan Ave., Washington, D.C., 20010, USA

    Nadja Kadom

  2. Department of Neurology, Children’s National Medical Center, Washington, D.C., USA

    Tammy Tsuchida & William D. Gaillard

Authors
  1. Nadja Kadom
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  2. Tammy Tsuchida
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  3. William D. Gaillard
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Correspondence to Nadja Kadom.

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Kadom, N., Tsuchida, T. & Gaillard, W.D. Hippocampal sclerosis in children younger than 2 years. Pediatr Radiol 41, 1239–1245 (2011). https://doi.org/10.1007/s00247-011-2166-4

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  • DOI: https://doi.org/10.1007/s00247-011-2166-4

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