Skip to main content
SpringerLink
Log in

Radiological approach to disorders of arterial brain vessels associated with childhood arterial stroke—a comparison between MRA and contrast angiography

  • Mini-symposium: Stroke in children
  • Published:
Pediatric Radiology Aims and scope Submit manuscript

Abstract

Recent studies of arterial ischaemic stroke in children have emphasised the higher frequency of cerebral arterial abnormalities than believed previously, explaining some of the strokes thought to have been idiopathic. Moreover, recurrent strokes are significantly more frequent in children with multiple risk factors, including those with demonstrable vascular abnormalities. Thus, cerebral arterial imaging is essential for the understanding and therapeutic approach to this pathology. Contrast angiography (CA) is the reference examination for the diagnosis of cerebral arterial abnormalities, but MR angiography (MRA) is a sensitive and non-invasive method to evaluate the vasculopathy of childhood stroke. In this article we highlight recent data concerning localisation and characterisation of arterial lesions and discuss the yield of MRA compared with CA.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1.
Fig. 2.
Fig. 3.
Fig.4.
Fig. 5.
Fig. 6.

Similar content being viewed by others

References

  1. Lynch J, Hirtz D, deVeber G, et al (2002) Report of the National Institute of Neurological Disorders and stroke workshop on perinatal and childhood stroke. Pediatrics 109:116–123

    PubMed  Google Scholar 

  2. Giroud M, Lemesle M, Gouyon JB, et al (1995) Cerebro-vascular disease in children under 16 years of age in the city of Dijon, France. J Clin Epidemiol 48:1343–1348

    Article  CAS  PubMed  Google Scholar 

  3. Ganesan V, Prengler M, McShane MA, et al (2003) Investigation of risk factors in children with arterial ischemic stroke. Ann Neurol 53:167–173

    Article  PubMed  Google Scholar 

  4. Lanthier S, Carmant L, David M, et al (2000) Stroke in children: the coexistence of multiple risk factors predicts poor outcome. Neurology 54:371–378

    CAS  PubMed  Google Scholar 

  5. Lee BC, Park TS, Kaufman BA (1995) MR angiography in pediatric neurological disorders. Pediatr Radiol 25:409–419

    CAS  PubMed  Google Scholar 

  6. Rollins N, Dowling M, Booth T, et al (2000) Idiopathic ischemic cerebral infarction in childhood: depiction of arterial abnormalities by MR angiography and catheter angiography. AJNR Am J Neuroradiol 21:549–556

    CAS  PubMed  Google Scholar 

  7. Husson B, Rodesch G, Lasjaunias P, et al (2002) Magnetic resonance angiography in childhood arterial brain infarcts: a comparative study with contrast angiography. Stroke 33:1280–1285

    Article  PubMed  Google Scholar 

  8. Brower MC, Rollins N, Roach ES (1996) Basal ganglia and thalamic infarction in children: cause and clinical features. Arch Neurol 53:1252–1256

    CAS  PubMed  Google Scholar 

  9. Satoh S, Shirane R, Yoshimoto T (1991) Clinical survey of ischemic cerebrovascular disease in a district of Japan. Stroke 22:586–589

    CAS  PubMed  Google Scholar 

  10. Harwood-Nash DC, McDonald P, Argent W (1971) Cerebral arterial disease in children AJR Am J Roentgenol 111:672–686

    CAS  Google Scholar 

  11. Chabrier S, Rodesch G, Lasjaunias P, et al (1998) Transient cerebral arteriopathy: a disorder recognized by serial angiograms in children with stroke. J Child Neurol 13:27–32

    CAS  PubMed  Google Scholar 

  12. Lanthier S, Lortie A, Michaud J, et al (2001) Isolated angiitis of the CNS in children. Neurology 56:837–842

    CAS  PubMed  Google Scholar 

  13. Fullerton HJ, Johnston SC, Smith WS (2001) Arterial dissection and stroke in children. Neurology 57:1155–1160

    CAS  PubMed  Google Scholar 

  14. Chabrier S, Lasjaunias P, Husson B, et al (2003) Ischaemic stroke from dissection of craniocervical arteries in childhood: report of 12 patients. Eur J Paediatr Neurol 7:39–42

    Article  PubMed  Google Scholar 

  15. Askalan R, Laughlin S, Mayank S (2001) Chickenpox and stroke in childhood: a study of frequency and causation. Stroke 32:1257–1262

    CAS  PubMed  Google Scholar 

  16. Sébire G, Meyer L, Chabrier S (1999) Varicella as a risk factor for cerebral infarction in childhood: a case-control study. Ann Neurol 45:679–680

    Article  PubMed  Google Scholar 

  17. Singhal AB, Singhal BS, Ursekar MA, et al (2001) Serial MR angiography and contrast-enhanced MRI in chickenpox-associated stroke. Neurology 56:815–817

    CAS  PubMed  Google Scholar 

  18. Berger TM, Caduff JH, Gebbers JO (2000) Fatal varicella-zoster virus antigen-positive giant cell arteritis of the central nervous system. Pediatr Infect Dis 19:653–656

    Article  CAS  Google Scholar 

Download references

Acknowledgement

The authors wish to thank G. Sébire for his help with the preparation of this manuscript.

Author information

Authors and Affiliations

  1. Service de Radiopédiatrie, Centre Hospitalier Universitaire de Bicêtre, 78 rue du Général Leclerc, 94275 Le Kremlin Bicêtre Cedex, France

    Béatrice Husson

  2. Service de Neuroradiologie, Hôpital Bicêtre, Université Paris XI, Le Kremlin Bicêtre, France

    Pierre Lasjaunias

Authors
  1. Béatrice Husson
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Pierre Lasjaunias
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Béatrice Husson.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Husson, B., Lasjaunias, P. Radiological approach to disorders of arterial brain vessels associated with childhood arterial stroke—a comparison between MRA and contrast angiography. Pediatr Radiol 34, 10–15 (2004). https://doi.org/10.1007/s00247-003-1109-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00247-003-1109-0

Keywords

Search

Navigation