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Special report on the 2007 adult and pediatric Position Development Conferences of the International Society for Clinical Densitometry

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Abstract

The International Society for Clinical Densitometry (ISCD) conducts Position Development Conferences (PDCs) for the purpose of establishing standards and guidelines in the field of bone densitometry. Topics for consideration are selected according to clinical relevance, a perceived need for standardization, and the likelihood of achieving agreement. Questions regarding nomenclature, indications, acquisition, analysis, quality control, interpretation, and reporting of bone density tests for each topic area are assigned to task forces for a comprehensive review of the scientific literature. The findings of the review and recommendations are then presented to an international panel of experts at the PDC. The expert panel votes on potential Official Positions for appropriateness, necessity, quality of the evidence, strength of the recommendation, and applicability (worldwide or variable according to local requirements). Recommendations that are approved by the ISCD Board of Directors become Official Positions. The first Pediatric PDC was 20–21 June 2007 in Montreal, QC, Canada. The most recent Adult PDC was held 20–22 July 2007, in Lansdowne, VA, USA. This Special Report summarizes the methodology of the ISCD PDCs and presents selected Official Positions of general interest.

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Notes

  1. Application of recommendation may vary according to local requirements.

  2. Application of recommendation may vary according to local requirements.

  3. Other hip regions of interest, including Ward’s area and the greater trochanter, should not be used for diagnosis. Application of recommendation may vary according to local requirements.

  4. VFA is designed to detect vertebral fractures and not other abnormalities.

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Conflicts of interest

S. Baim: none.

N. Binkley: consultant for Merck, Novartis, Lilly; research funding from Merck, Novartis, Roche, Aventis, GSK, Deltanoid; speaker for Merck, Roche, P&G, GSK.

D.B. Hans: ownership interest in Synarc, Inc.; research funding from Servier.

D.L. Kendler: consultant for Merck, Pfizer, Servier, Lilly, Novartis, Amgen; educational grants from Merck, Pfizer, Servier, Lilly, Novartis, Amgen, P&G; honoraria from Merck, Pfizer, Servier, Lilly, Novartis, Amgen, P&G; research funding from Merck, Pfizer, Servier, Lilly, Novartis, Amgen, P&H, Takeda, Wyeth, Zelos, J&J; speaker for Merck, Servier, Lilly, Novartis, Amgen, P&G.

E.M. Lewiecki: committee chair for ISCD; educational grants from P&G, Amgen, Novartis; honoraria from Merck, Lilly, P&G, Roche, GSK, Novartis; officer or board member for ISCD; ownership interest in GE Healthcare, P&G; research funding from Merck, P&G, Roche, Lilly, Amgen, Novartis; speaker for Merck, Lilly, P&G, Roche, GSK, Novartis.

J.P. Bilezikian: consultant for P&G, sanofi-aventis, Merck, Amgen, Lilly; officer or board member for P&G, sanofi-aventis, Merck, Amgen, Lilly.

S.L. Silverman: consultant for Merck, P&G, Wyeth, Roche, Novartis; officer or board member for Compumed; research funding from Novartis, Lilly, Wyeth, Roche, P&G, Merck; speaker for Lilly, Merck, P&G, Roche.

M.B. Leonard: None.

M.-L. Bianchi: educational grants from Telethon; VILDM research funding from Telethon.

H. Kalkwarf: employee of P&G; stock in P&G.

F. Rauch: none.

C.B. Langman: director of institutional research for Amgen: research funding from Amgen.

H. Plotkin: none.

N.J. Bishop: consultant for P&G; research funding from Alliance for Better Bone Health, Novartis.

C.M. Gordon: none.

B.S. Zemel: consultant for Johnson & Johnson; research funding from Quest Diagnostics, Nichols Research Institute.

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Correspondence to E. M. Lewiecki.

Appendices

Appendices

Appendix 1: Key 2007 Adult PDC participants

Adult PDC expert panelists

H.K. Genant, University of California at San Francisco, San Francisco, CA, USA

C.C. Glueer, University Hospital CAU Kiel, Kiel, Germany

A. Itabashi, Saitama Medical School, Moroyama, Saitama, Japan

L.G. Jankowski, CDT Illinois Bone and Joint Institute, Morton Grove, IL, USA

M. Kleerekoper, Saint Joseph Mercy Reichert Health Center, Ypsilanti, MI, USA

W.D. Leslie, St. Boniface General Hospital, Winnipeg, MB, Canada

M. Luckey, St. Barnabas Osteoporosis & Metabolic Bone Disease Center, Livingston, NJ, USA

P.D. Miller, Colorado Center for Bone Research, Lakewood, CO, USA

S. Ortolani, Istituto Auxologico Italiano, Milan, Italy

S. Petak, Texas Institute for Reproductive Medicine & Endocrinology, Houston, TX, USA

L.G. Raisz, University of Connecticut Health Center, Farmington, CT, USA

D.L. Schneider, University of California San Diego School of Medicine, La Jolla, CA, USA

Technical Issues Task Force Chair

C. Simonelli, HealthEast Clinics, Woodbury, MN, USA

Vertebral Fracture Assessment (VFA) Task Force Chair

J. Schousboe, Park Nicollet Clinic, St. Louis Park, MN, USA

QCT/pQCT Task Force Chair

K. Engelke, University of Erlangen, Erlangen, Germany

QUS Task Force Chair

M.-A. Krieg, University Hospital, Lausanne, Vaud, Switzerland

pDXA Task Force Chairs

D.M. Reid, University of Aberdeen, Aberdeen, UK; E.N. Schwartz, Northern California Institute for Bone Health, Oakland, CA

Adult PDC steering committee

Chair: S. Baim, Medical College of Wisconsin, Milwaukee, WI, USA

N. Binkley, University of Wisconsin, Madison, WI, USA

D.B. Hans, Geneva University Hospital, Geneva, Switzerland

D.L. Kendler, Clinical Research Centre, Vancouver, BC, Canada

E.M. Lewiecki, New Mexico Clinical Research & Osteoporosis Center, Albuquerque, NM, USA

Adult PDC moderators

J.P. Bilezikian, College of Physicians and Surgeons, New York, NY, USA

S.L. Silverman, Osteoporosis Medical Center, Beverly Hills, CA, USA

Appendix 2: Key 2007 Pediatric PDC participants

Pediatric PDC expert panelists

S.L. Bass, Deakin University, Burwood, VIC, Australia

T.O. Carpenter, Yale University School of Medicine, New Haven, CT, USA

E. Clark, Bristol Royal Infirmary, Bristol, UK

B.A. Cromer, Metro Health Medical Center, Cleveland, OH, USA

T. Cundy, University of Auckland, Auckland, New Zealand

F.H. Glorieux, Shriners Hospital for Children, Montreal, QC, Canada

G. El-Hajj Fuleihan, American University of Beirut, Beirut, Lebanon

S.C. Kaste, St. Jude Children’s Research Hospital, Memphis, TN, USA

G.L. Klein, University of Texas Medical Branch Child Health Center, Galveston, TX, USA

R.S. Lorenc, Specjalistyczny Osrodek Medycyny Wieku, Warsaw, Poland

M.Z. Mughal, St. Mary’s Hospital, Manchester, UK

A.J. Sawyer, San Ramon Regional Medical Center, San Ramon, CA USA

F.A. Sylvester, Connecticut Children’s Medical Center, Hartford, CT USA

H.Tanaka, Okayama University Graduate School of Medicine & Dentistry, Okayama, Japan

Task force chairs for the definitions of osteoporosis in children and adolescents

F. Rauch, Shriners Hospital for Children, Montreal, QC, Canada

H. Plotkin, Children’s Hospital and University of Nebraska Medical Center, Omaha, NE, USA

Task force chair for DXA assessment in children and adolescents with diseases that may affect the skeleton

N.J. Bishop, MRCP, MD, University of Sheffield, Sheffield, United Kingdom

Task force chair for DXA interpretation and reporting of bone densitometry in children and adolescents

C.M. Gordon, Children’s Hospital Boston, Boston, MA, USA

Task force chair for peripheral quantitative computed tomography in children and adolescents

B.S. Zemel, The Children’s Hospital of Philadelphia, Philadelphia, PA, USA

Pediatric PDC steering committee

Co-chair: S. Baim, Medical College of Wisconsin, Milwaukee, WI, USA

Co-chair: M.B. Leonard, Children’s Hospital of Philadelphia, Philadelphia, PA, USA

M.-L. Bianchi, Istituto Auxologico Italiano IRCCS, Milan, Italy

D.B. Hans, Geneva University Hospital, Geneva, Switzerland

H. Kalkwarf, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA

F. Rauch, Shriners Hospital for Children, Montreal, QC, Canada

Pediatric PDC moderators

C.B. Langman, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA

S. Baim, Medical College of Wisconsin, Milwaukee, WI, USA

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Lewiecki, E.M., Gordon, C.M., Baim, S. et al. Special report on the 2007 adult and pediatric Position Development Conferences of the International Society for Clinical Densitometry. Osteoporos Int 19, 1369–1378 (2008). https://doi.org/10.1007/s00198-008-0689-9

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  • DOI: https://doi.org/10.1007/s00198-008-0689-9

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