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Porcine skin collagen implants for anterior vaginal wall prolapse: a randomised prospective controlled study

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Abstract

Introduction and hypothesis

The effect of a Pelvicol® graft compared with a conventional anterior vaginal repair was evaluated in this randomised controlled study.

Methods

Only patients with a stage II or higher (Ba ≥ −1) defect were included.

Results

Thirty-one patients were allocated to a conventional anterior repair; 30 to Pelvicol® graft. At 12 months follow-up, four patients among controls (15%) and two in the graft group (7%) had objective recurrence. Among controls, the difference at 3 months follow-up in Ba was 6.0 cm when compared with the position of Ba prior to surgery. In the graft group, the difference was 7.0 cm (P < 0.05). This difference was still present at 12 months follow-up (6.0 vs. 7.0 cm; P < 0.05).

Conclusions

The implantation of a Pelvicol® graft does not improve the POP-Q stage.

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Authors and Affiliations

  1. Department of Obstetrics and Gynaecology, Roskilde University Hospital, 7-13 Køgevej, 4000, Roskilde, Denmark

    Ulla Hviid & Martin Rudnicki

  2. Department of Clinical Biochemistry, Roskilde University Hospital, 7-13 Køgevej, 4000, Roskilde, Denmark

    Thomas Vauvert F. Hviid

Authors
  1. Ulla Hviid
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  2. Thomas Vauvert F. Hviid
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  3. Martin Rudnicki
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Correspondence to Martin Rudnicki.

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Hviid, U., Hviid, T.V.F. & Rudnicki, M. Porcine skin collagen implants for anterior vaginal wall prolapse: a randomised prospective controlled study. Int Urogynecol J 21, 529–534 (2010). https://doi.org/10.1007/s00192-009-1018-3

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  • DOI: https://doi.org/10.1007/s00192-009-1018-3

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