Abstract
The purpose of our study is to evaluate whether the hamstring tendons can regrow after harvesting for anterior cruciate ligament (ACL) reconstruction and whether the regenerate tissue can be histologically characterized as tendinous. Eleven of the patients (eight female and three male; mean age, 23 years; range 17–37 years) consented to participate in this study. One year after the ACL reconstruction, surgical biopsy was done. Regeneration of the tendon was detected macroscopically in 9 of the 11 patients. Histologically and immunohistochemically, the regenerated tendons closely resembled normal ones. The results of this study show the hamstring tendons can regenerate after harvesting for the ACL reconstruction.
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Cross MJ, Roger G, Kujima P, Anderson IF (1992) Regeneration of the semitendinosus and gracilis tendons following their transaction for repair of the anterior cruciate ligament. Am J Sports Med 20:221–223
Eriksson K, Larsson H, Wredmark T, Hamberg P (1999) Semitendinosus tendon regeneration after harvesting for ACL reconstruction. A prospective MRI study. Knee Surg Sports Traumatol Arthrosc 7:220–225
Eriksson K, Kindblom LG, Hamberg P, Larsson H, Wredmark T (2001) The semitendinosus tendon regenerates after resection: a morphologic and MRI analysis in 6 patients after resection for anterior cruciate ligament reconstruction. Acta Orthop Scand 72:379–384
Ferretti A, Conteduca F, Morelli F, Masi V (2002) Regeneration of the semitendinosus tendon after its use in anterior cruciate ligament reconstruction. A histologic study of three cases. Am J Sports Med 30:204–207
Harrison RK, Mudera V, Grobbelaar AO, Jones ME, McGrouther DA (2003) Synovial sheath cell migratory response to flexor tendon injury: an experimental study in rats. J Hand Surg [Am] 28:987–993
Karns DJ, Heidt RS Jr, Holladay BR, Colosimo AJ (1994) Case report: revision anterior cruciate ligament reconstruction. Arthroscopy 10:148–151
Kartus J, Stener S, Lindahl S, Eriksson BI, Karlsson J (1994) Ipsi-or contralateral patellar tendon graft in anterior cruciate ligament revision surgery. A comparison of two methods. Am J Sports Med 26:499–504
LaPrade RF, Hamilton CD, Montgomery RD, Wentorf F, Hawkins HD (1997) The reharvested central third of the patellar tendon. A histologic and mechanical analysis. Am J Sports Med 25:779–785
O’Shea JJ, Shelbourne KD (2002) Anterior cruciate ligament reconstruction with a reharvested bone-patellar tendon-bone graft. Am J Sports Med 30:208–213
Papandrea P, Vulpiani MC, Ferretti A, Conteduca F (2000) Regenaration of the semitendinosus tendon harvested for anterior cruciate ligament reconstruction. Evaluation using ultrasound. Am J Sports Med 28:556–561
Rispoli DM, Sanders TG, Miller MD, Morrison WB (2001) Magnetic resonance imaging at different time periods following hamstring harvest for anterior cruciate ligament reconstruction. Arthroscopy 17:2–8
Tadokoro K, Matsui N, Yagi M, Kuroda R, Kurosaka M, Yoshiya S (2004) Evaluation of hamstring strength and tendon regrowth after harvesting for anterior cruciate ligament reconstruction. Am J Sports Med 32:1644–1650
Williams GN, Snyder-Mackler L, Barrance PJ, Axe MJ, Buchanan TS (2004) Muscle and tendon morphology after reconstruction of the anterior cruciate ligament with autologous semitendinosus-gracilis graft. J Bone Joint Surg [Am] 86:1936–1946
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No benefits in any form have been received or will be received from any commercial party related directly or indirectly to the subject of this article. No funds were received in support of this study.
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Okahashi, K., Sugimoto, K., Iwai, M. et al. Regeneration of the hamstring tendons after harvesting for arthroscopic anterior cruciate ligament reconstruction: a histological study in 11 patients. Knee Surg Sports Traumatol Arthr 14, 542–545 (2006). https://doi.org/10.1007/s00167-006-0068-z
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DOI: https://doi.org/10.1007/s00167-006-0068-z