Zusammenfassung
Schizophrenien sind häufig bereits im Frühstadium der Erkrankung von Einbußen im Bereich des psychosozialen Funktionsniveaus betroffen. Neuere Untersuchungen haben gezeigt, dass sozial-kognitive Störungen, wie etwa Schwierigkeiten, die Perspektive einer anderen Person einzunehmen (Mentalisierung), möglicherweise in kausalem Zusammenhang mit Beeinträchtigungen des psychosozialen Funktionsniveaus bei Schizophrenien stehen. Der vorliegende Beitrag dient dazu, diese Zusammenhänge kritisch zu beleuchten. Implikationen, die sich daraus ergeben, sind unter anderem eine stärkere Berücksichtigung sozial-kognitiver Trainingsmöglichkeiten in der Gesamtbehandlung schizophrener Störungen. Unklar ist bislang, ob die erzielten Effekte von verbesserter sozialer Kognition auf das psychosoziale Funktionsniveau über längere Zeit stabil bleiben. Dazu sind Längsschnittstudien erforderlich, die in diesem Bereich bislang fehlen.
Summary
Schizophrenia is characterised by impaired psychosocial functioning that is often already present in early stages of the disorder. Recent studies suggest that social-cognitive deficits such as mental perspective-taking or mentalising are causally linked with poor social functioning in schizophrenia. This article reviews the evidence for such an association. Findings imply the integration of social-cognitive training in a treatment concept for schizophrenia. However, to date it remains elusive whether or not the impact of improved social cognition on psychosocial functioning is stable over prolonged periods of time. To answer this open question requires longitudinal studies that are currently unavailable.
Literatur
Abdel-Hamid M, Lehmkämper C, Sonntag C et al (2009) Theory of mind in schizophrenia: The role of clinical symptomatology and neurocognition in understanding other people’s thoughts and intentions. Psychiatry Res 165:19–26
Abu-Akel A (1999) Impaired Theory of Mind in schizophrenia. Pragmat Cogn 7:247–282
Adolphs R (2001) The neurobiology of social cognition. Curr Opin Neurobiol 11(2):231–239
Aghotor J, Moritz S, Pfüller U et al (2007) Evaluation eines Metakognitiven Trainingsprogramms für schizophrene Patienten: Effekte auf die Positivsymptomatik. Posterpräsentation auf dem DGPPN-Kongress in Berlin
Baron-Cohen S, Wheelwright S, Hill J et al (2001) The „Reading the Mind in the Eyes“ test revised version: A study with normal adults, and adults with Asperger Syndrome or high-functioning autism. J Child Psychol Psychiatry 42:241–251
Bechdolf A, Juckel G (2006) Psychoedukation bei Personen mit erhöhtem Psychoserisiko. Schattauer, Stuttgart
Bleuler E (1911) Dementia praecox oder die Gruppe der Schizophrenien Deutike, Leipzig
Bömmer I, Brüne M (2006) Neuropsychologische Aspekte wahnhafter Störungen: Charakteristischer Attribuierungsstil oder kognitives Defizit? Nervenarzt in press
Bora E, Eryavuz A, Kayahan B et al (2006) Social functioning, theory of mind and neurocognition in outpatients with schizophrenia; mental state decoding may be a better predictor of social functioning than mental state reasoning. Psychiatry Res 145:95–103
Brüne M (2005) Theory of Mind in schizophrenia: A review of the literature. Schizophr Bull 31:21–42
Brüne M, Abdel-Hamid M, Lehmkämper C, Sonntag C (2007) Mental state attribution, neurocognitive functioning, and psychopathology: What predicts poor social competence in schizophrenia best? Schizophr Res 92:151–159
Brüne M, Brüne-Cohrs U (2006) Theory of Mind-evolution, ontogeny, brain mechanisms and psychopathology. Neurosci Biobehav Rev 30:437–455
Brüne M (2005b) Emotion recognition, ‚theory of mind’, and social behavior in schizophrenia. Psychiatry Res 133:135–147
Burns T, Patrick D (2007) Social functioning as an outcome measure in schizophrenia studies. Acta Psychiatr Scand 116:403–418
Combs DR, Adams SD, Penn DL et al (2007) Social Cognition and Interaction Training (SCIT) for inpatients with schizophrenia spectrum disorders: Preliminary findings. Schizophr Res 91:112–116
Conrad K (1959/1992) Die beginnende Schizophrenie. Versuch einer Gestaltanalyse des Wahns. 6. Aufl. Thieme, Stuttgart
Corcoran R, Frith CD (2003) Autobiographical memory and Theory of Mind: evidence of a relationship in schizophrenia. Psychol Med 33:897–905
Couture SM, Penn DL, Roberts DL (2006) The functional significance of social cognition in schizophrenia: A review. Schizophr Bull 32:44–63
Frith CD (1992) The cognitive neuropsychology of schizophrenia. Lawrence Erlbaum Associates, Hove, UK
Gigerenzer G (1997) The modularity of social intelligence. In: White A, Byrne RW (eds) Machiavellian Intelligence II: Extensions and Evaluations. Cambridge Univ Press, Cambridge, pp 264–288
Gottesman II, Gould TD (2003) The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry 160:636–645
Green MF, Olivier B, Crawley JN et al (2005) Social cognition in schizophrenia: Recommendations from the Measurement and Treatment Research to Improve Cognition in Schizophrenia New Approaches conference. Schizophr Bull 31(4):882–887
Hardy-Baylé MC (1994) Organisation de l‘action, phénomènes de conscience et représentation mentale de l‘action chez des schizophrènes. Actual Psychiatr 20:393–400
Harrington L, Siegert RJ, McClure J (2005) Theory of Mind in schizophrenia: a critical review. Cognit Neuropsychiatry 10:249–286
Heinrichs DW, Hanlon TE, Carpenter WT Jr (1984) The Quality of life scale: an instrument for rating the schizophrenic deficit syndrome. Schizophr Bull 10(3):388–398
Janssen I, Krabbendam L, Jolles J, van Os J (2003) Alterations in theory of mind in patients with schizophrenia and non-psychotic relatives. Acta Psychiatr Scand 108:110–117
Juckel G, Schaub D, Fuchs N et al (2008) Validation of the personal and social performance (PSP) scale in a german sample of acutely ill patients with schizophrenia. Schizophr Res 104(1–3):287–293
Kölkebeck K, Abdel-Hamid M, Ohrmann P, Brüne M (2008) Theory of Mind bei Schizophrenien: Klinische und wissenschaftliche Aspekte. Fortschr Neurol Psychiatr 76:573–582
Langdon R, Michie PT, Ward PB et al (1997) Defective self and/ or other mentalising in schizophrenia: A cognitive neuropsychological approach. Cogn Neuropsychiatry 2:167–193
Leslie A (1987) Pretence and representation: The origins of ‚theory of mind’. Psychol Rev 94:412–442
Lysaker PH, Dimaggio G, Carcione A et al (2009) Metacognition and schizophrenia: The capacity for self-reflectivity as a predictor for prospective assessments of work performance over six months. Schizophr Res (in press)
Lysaker PH, Carcione A, Dimaggio G et al (2005) Metacognition amidst narratives of self and illness in schizophrenia: associations with neurocognition, symptoms, insight and quality of life. Acta Psychiatr Scand 112:64–71
Mazza M, De Risio A, Surian L et al (2001) Selective impairments of Theory of Mind in people with schizophrenia. Schizophr Res 47:299–308
Mizrahi R, Kiang M, Mamo DC et al (2006) The selective effect of antipsychotics on the different dimensions of the experience of psychosis in schizophrenia spectrum disorders. Schizophr Res 88:111–118
Moritz S, Woodward TS, Burlon M (2005) Metakognitives Training für schizophrene Patienten (MKT). Manual. VanHam Campus, Hamburg
Morosini PL, Magliano L, Brambilla L et al (2000) Development, reliability and acceptability of a new version of the DSM-IV Social and Occupational Functioning Assessment Scale (SOFAS) to assess routine social functioning. Acta Psychiatr Scand 1001:323–329
Naber D, Karow A, Lambert M (2002) Psychosocial outcomes in patients with schizophrenia: Quality of life and reintegration. Curr Opin Psychiatry 15(1):31–36
Naber D, Moritz S, Lambert M et al (2001) Schizophrenic psychopathology and subjective well-being under neuroleptics. Schizophr Res 50:79–88
Newen A, Vogeley K (2003) Self-representation: searching for a neural signature of self-consciousness. Conscious Cogn 12(4):529–543
Penn DL, Roberts DL, Combs D, Sterne A (2007) Best practices: The Development of the Social Cognition and Interaction Training program for schizophrenia spectrum disorders. Psychiatr Serv 58(4):449–451
Penn DL, Sanna LJ, Roberts DL (2008) Social cognition in schizophrenia: A review. Schizophr Bull 34: 408–411. doi:10.1093/schbul/sbn014
Penn DL, Corrigan PW, Bentall RP et al (1997) Social cognition in schizophrenia. Psychol Bull 121:114–132
Pickup GJ, Frith CD (2001) Theory of Mind impairments in schizophrenia: symptomatology, severity and specificity. Psychol Med 31:207–220
Pinkham AE, Penn DL, Perkins DO, Lieberman J (2003) Implications for the neural basis of social cognition for the study of schizophrenia. Am J Psychiatry 160:815–824
Premack D, Woodruff G (1978) Does the chimpanzee have a „Theory of Mind“? Behav Brain Sci 4:515–526
Roberts DL, Penn DL (2009) Social cognition and interaction training (SCIT) for outpatients with schizophrenia: a preliminary study. Psychiatry Res 30:166(2–3):141–147
Roberts DL, Penn DL (2006) Social Cognition and Interaction Training (SCIT), Training Manual. Unpublished manuscript
Roder V, Brenner HD, Kienzle N, Hodel B (1997) Integriertes psychologisches Therapieprogramm für schizophrene Patienten (IPT). 4. Aufl. Beltz, Weinheim
Roder V, Brenner HD, Müller D et al (2002) Development of specific social skills training programmes for schizophrenia patients: results of a multicentre study. Acta Psychiatr Scand 105(5):363–371
Roder V, Mueller DR, Mueser KT, Brenner HD (2006) Integrated psychological therapy (IPT) for schizophrenia: is it effective? Schizophr Bull 32(1):81–93
Roncone R, Falloon IRH, Mazza M et al (2002) Is theory of mind in schizophrenia more strongly associated with clinical and social functioning than with neurocognitive deficits? Psychopathology 35:280–288
Sarfati Y, Hardy-Baylé MC, Brunet E, Widlöcher D (1999) Investigating theory of mind in schizophrenia: influence of verbalization in disorganized and non-disorganized patients. Schizophr Res 37:183–190
Semerari A, Carcione A, Dimaggio G (2003) How to evaluate metacognitive function in psychotherapy? The Metacognition Assessment Scale and its applications. Clin Psychol Psychother 10:238–261
Sprong M, Schothorst P, Vos E et al (2007) Theory of mind in schizophrenia. Br J Psychiatry 191:5–13
Van Hooren S, Versmissen D, Janssen I et al (2008) Social cognition and neurocognition as independent domains in psychosis. Schizophr Res 103:257–265
Vogeley K, Bussfeld P, Newen A et al (2001) Mind reading: neural mechanisms of theory of mind and self-perspective. Neuroimage 14(1):170–181
WHO (1988) WHO Psychiatric Disability Assessment Schedule (WHO/DAS). WHO, Genf
Wykes T, Sturt E (1986) The measurement of social behaviour in psychiatric patients: an assessment of the reliability and validity of the SBS schedule. Br J Psychiatry 148:1–11
Patterson TL, Moscona S, McKibbin CL et al (2001) Social skills performance assessment among older patients with schizophrenia. Schizophr Res 48:351–360
Interessenskonflikte
Der korrespondierende Autor gibt an, dass kein Interessenkonflikt besteht.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Brüne, M., Juckel, G. Soziale Kognition bei Schizophrenien. Nervenarzt 81, 339–346 (2010). https://doi.org/10.1007/s00115-009-2841-y
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00115-009-2841-y
Schlüsselwörter
- Schizophrenie
- Soziale Kognition
- Mentalisierung
- Psychosoziales Funktionsniveau
- Sozial-kognitiver Trainingsmöglichkeiten