Skip to main content
Log in

Ökonomische Aspekte in der chirurgischen Wundbehandlung

Economic aspects of surgical wound therapies

  • Leitthema
  • Published:
Der Chirurg Aims and scope Submit manuscript

Zusammenfassung

Hintergrund

In Deutschland wenden die Krankenversicherungen derzeit alleine für die Behandlung des Dekubitus, der diabetischen Fußulzera und Ulcera cruris pro Jahr rund 5 Mrd. Euro nur an Sachkosten auf. Vor diesem Hintergrund sind Überlegungen zur ökonomischen Bedeutung der Wundbehandlung dringend erforderlich.

Methoden

Aufgrund der mangelnden evidenzgesicherten Datenlage zur Ökonomie der Wundbehandlung wird beispielhaft anhand klinischer Studien untersucht, welche Kostenrelevanz sich durch eine Umstellung von Feuchtverbänden auf andere Therapieansätze ergeben würde. Die geeigneten medizinischen Parameter werden jeweils mit den anfallenden Behandlungskosten bewertet und miteinander verglichen.

Ergebnisse

Anhand der bisher publizierten Daten können unterschiedliche Therapieansätze im Einzelfall zu einem frühzeitigeren Wundschluss mit reduzierter Komplikationsfrequenz, Verringerung von Krankenhauseinweisungen und Reduktion von Krankenhausverweiltagen führen. Trotz häufig erhöhter Tagesbehandlungskosten ergeben sich auf Grundlage solcher Daten Kostenvorteile im Vergleich zu anderen Therapiemodalitäten.

Schlussfolgerung

Obwohl aufgrund zahlreicher Faktoren wie variabler Komorbiditäten und häufiger Multimorbidität bei problematischen Wunden derzeit nur eine unzureichende Evidenz für die Effektivität und Effizienz verschiedener Modalitäten existiert, zeigt bereits die kritische Evaluation eines einzigen innovativen Therapieverfahrens im Vergleich zur Standardbehandlung, dass ein bei vordergründiger Betrachtung scheinbar teures Therapieverfahren im Einzelfall und in einem größeren ökonomischen Zusammenhang teils enorme Einsparpotenziale in sich bergen kann. Wichtig ist, die konservativen Behandlungsstrategien in operative chirurgische Konzepte einzubetten.

Abstract

Introduction

Health care insurers in Germany pay 5 billion Euros annually in materials alone for pressure ulcers, diabetic foot ulcers, and ulcus cruris. With such figures it is necessary to consider, economic aspects of treatment.

Methods

Due to the lack of evidence-based data on wound treatment costs, we investigated available studies for an effect on treatment costs when standard moist wound therapy was compared with alternative methods. Suited medical parameters are calculated and compared. Daily costs and length of treatment are correlated and compared.

Results

Published data show that alternative wound therapies may lead to an earlier wound closure, fewer complications, and reduction in hospital admissions and length of stay. Despite higher daily costs, some alternative wound therapies turn out to be more cost effective, when all economical factors are considered. In this respect a move towards alternative wound therapies could possibly lead to major savings.

Discussion

At present there is insufficient evidence to prove the efficacy of various treatment modalities for chronic wounds. This is due to numerous factors such as comorbidities and frequent multimorbidity. Nevertheless critical evaluation of one innovative treatment alone already uncovered an enormous potential for savings in a wider economic context, despite the comparatively higher cost of a single treatment. It is of utmost importance that conservative wound care become firmly embedded in surgical concepts.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abb. 1
Abb. 2
Abb. 3
Abb. 4
Abb. 5

Literatur

  1. Kopp J, Wang GY, Kulmburg P et al. (2004) Accelerated wound healing by in vivo application of keratinocytes overexpressing KGF. Mol Ther 10: 86–96

    Article  CAS  PubMed  Google Scholar 

  2. Kopp J, Jeschke MG, Bach AD et al. (2004) Applied tissue engineering in the closure of severe burns and chronic wounds using cultured human autologous keratinocytes in a natural fibrin matrix. Cell Tissue Bank 5: 89–96

    Article  CAS  PubMed  Google Scholar 

  3. Voigt M, Schauer M, Schaefer DJ et al. (1999) Cultured epidermal keratinocytes on a microspherical transport system are feasible to reconstitute the epidermis in full-thickness wounds. Tissue Eng 5: 563–572

    Article  CAS  PubMed  Google Scholar 

  4. Bannasch H, Stark GB, Knam F et al. (2008) Decellularized dermis in combination with cultivated keratinocytes in a short- and long-term animal experimental investigation. J Eur Acad Dermatol Venereol 22: 41–49

    CAS  PubMed  Google Scholar 

  5. Kneser U, Polykandriotis E, Ohnolz J et al. (2006) Engineering of vascularized transplantable bone tissues: induction of axial vascularization in an osteoconductive matrix using an arteriovenous loop. Tissue Eng 12: 1721–1731

    Article  CAS  PubMed  Google Scholar 

  6. Horch RE (2006) Future perspectives in tissue engineering. J Cell Mol Med 10: 4–6

    Article  PubMed  Google Scholar 

  7. Bleiziffer O, Eriksson E, Yao F et al. (2007) Gene transfer strategies in tissue engineering. J Cell Mol Med 11: 206–223

    Article  CAS  PubMed  Google Scholar 

  8. Stern-Straeter J, Bach AD, Stangenberg L et al. (2005) Impact of electrical stimulation on three-dimensional myoblast cultures – a real-time RT-PCR study. J Cell Mol Med 9: 883–892

    Article  CAS  PubMed  Google Scholar 

  9. Polykandriotis E, Arkudas A, Beier JP et al. (2007) Intrinsic axial vascularization of an osteoconductive bone matrix by means of an arteriovenous vascular bundle. Plast Reconstr Surg 120: 855–868

    Article  CAS  PubMed  Google Scholar 

  10. Seyhan H, Hamzavi J, Wiercinska E et al. (2006) Liver fibrogenesis due to cholestasis is associated with increased Smad7 expression and Smad3 signaling. J Cell Mol Med 10: 922–932

    Article  CAS  PubMed  Google Scholar 

  11. Will J, Melcher R, Treul C et al. (2008) Porous ceramic bone scaffolds for vascularized bone tissue regeneration. J Mater Sci Mater Med (in press)

  12. Polykandriotis E, Arkudas A, Euler S et al. (2006) Prevascularisation strategies in tissue engineering. Handchir Mikrochir Plast Chir 38: 217–223

    Article  CAS  PubMed  Google Scholar 

  13. Fiegel HC, Kaufmann PM, Bruns H et al. (2007) Review: hepatic tissue engineering. J Cell Mol Med 11: 206–223

    Article  CAS  Google Scholar 

  14. Bach AD, Beier JP, Stern-Staeter J, Horch RE (2004) Skeletal muscle tissue engineering. J Cell Mol Med 8: 413–422

    Article  CAS  PubMed  Google Scholar 

  15. Kneser U, Schaefer DJ, Polykandriotis E, Horch RE (2006) Tissue engineering of bone: the reconstructive surgeon’s point of view. J Cell Mol Med 10: 7–19

    Article  CAS  PubMed  Google Scholar 

  16. Munster AM (1992) Use of cultured epidermal autograft in ten patients. J Burn Care Rehabil 13: 124–126

    CAS  PubMed  Google Scholar 

  17. Horch RE, Bannasch H, Kopp J et al. (1998) Single-cell suspensions of cultured human keratinocytes in fibrin-glue reconstitute the epidermis. Cell Transplant 7: 309–317

    Article  CAS  PubMed  Google Scholar 

  18. Horch RE, Bannasch H, Stark GB (2001) Transplantation of cultured autologous keratinocytes in fibrin sealant biomatrix to resurface chronic wounds. Transplant Proc 33: 642–644

    Article  CAS  PubMed  Google Scholar 

  19. Horch RE, Debus M, Wagner G, Stark GB (2000) Cultured human keratinocytes on type I collagen membranes to reconstitute the epidermis. Tissue Eng 6: 53–67

    Article  CAS  PubMed  Google Scholar 

  20. Horch RE, Kopp J, Kneser U et al. (2005) Tissue engineering of cultured skin substitutes. J Cell Mol Med 9: 592–608

    Article  PubMed  Google Scholar 

  21. Horch RE, Horbach T, Lang W (2007) The nutrient omentum free flap: revascularization with vein bypasses and greater omentum flap in severe arterial ulcers. J Vasc Surg 45: 837–840

    Article  PubMed  Google Scholar 

  22. Lang W, Horch RE (2006) Distal extremity reconstruction for limb salvage in diabetic foot ulcers with pedal bypass, flap plasty and vacuum therapy. Zentralbl Chir [Suppl 1] 131: 146–150

  23. Anderson I (2000) Quality of life and leg ulcers: will NHS reform address patient need? Br J Nurs 9: 830–832, 834, 836

    CAS  PubMed  Google Scholar 

  24. Apelqvist J, Armstrong DG, Lavery LA, Boulton AJ (2008) Resource utilization and economic costs of care based on a randomized trial of vacuum-assisted closure therapy in the treatment of diabetic foot wounds. Am J Surg (in press)

  25. Chaby G, Senet P, Vaneau M et al. (2007) Dressings for acute and chronic wounds: a systematic review. Arch Dermatol 143: 1297–1304

    Article  PubMed  Google Scholar 

  26. Dissemond J (2007) Practical consequences after MRSA identification in chronic wounds. Hautarzt 58: 952–958

    Article  CAS  PubMed  Google Scholar 

  27. Gordon L, Edwards H, Courtney M et al. (2006) A cost-effectiveness analysis of two community models of care for patients with venous leg ulcers. J Wound Care 15: 348–353

    CAS  PubMed  Google Scholar 

  28. Hartmann M, Schulz D, Gundermann C, Norgauer J (2007) Economic aspects of standardization of modern wound care. Hautarzt 58: 970–974

    Article  CAS  PubMed  Google Scholar 

  29. Horch RE, Jeschke M, Loos B et al. (2003) Ulcus cruris – Chirurgische Verfahrenswahl, Debridement, Shaving, Fasziektomie, Transplantation. MedReport 27: 8–13

    Google Scholar 

  30. Queen D, Orsted H, Sanada H, Sussman G (2004) A dressing history. Int Wound J 1: 59–77

    Article  PubMed  Google Scholar 

  31. Vogt KC, Uhlyarik M, Schroeder TV (2007) Moist wound healing compared with standard care of treatment of primary closed vascular surgical wounds: a prospective randomized controlled study. Wound Repair Regen 15: 624–627

    Article  PubMed  Google Scholar 

  32. Horch RE (2004) Basics foundation and results of the vacuum therapy in the reconstructive surgery. Zentralbl Chir [Suppl 1] 129: S2–S5

  33. Horch RE et al. (2000) Vacuum assisted closure coverage of extensive soft tissue defects and skin graft fication. ZfW J Wound Healing 5: 17–19

    Google Scholar 

  34. Kopp J, Strnad V, Bach AD et al. (2005) Vacuum application increases therapeutic safety and allows intensified local radiation treatment of malignant soft-tissue tumors. Strahlenther Onkol 181: 124–130

    Article  PubMed  Google Scholar 

  35. Loos B, Kopp J, Hohenberger W, Horch RE (2007) Post-malignancy irradiation ulcers with exposed alloplastic materials can be salvaged with topical negative pressure therapy (TNP). Eur J Surg Oncol 33: 920–925

    CAS  PubMed  Google Scholar 

  36. Morykwas MJ, Argenta LC (1997) Nonsurgical modalities to enhance healing and care of soft tissue wounds. J South Orthop Assoc 6: 279–288

    CAS  PubMed  Google Scholar 

  37. Morykwas MJ, Argenta LC, Shelton-Brown EI, McGuirt W (1997) Vacuum-assisted closure: a new method for wound control and treatment: animal studies and basic foundation. Ann Plast Surg 38: 553–562

    Article  CAS  PubMed  Google Scholar 

  38. Morykwas MJ, David LR, Schneider AM et al. (1999) Use of subatmospheric pressure to prevent progression of partial-thickness burns in a swine model. J Burn Care Rehabil 20: 15–21

    CAS  PubMed  Google Scholar 

  39. Nord D (2006) Cost-effectiveness in wound care. Zentralbl Chir [Suppl 1] 131: 185–188

  40. Kottner J, Mertens E, Dassen T (2007) Pressure ulcer prevalence in Germany: results of a cross-sectional study in 2006. Pflege Z 60: 28–31

    PubMed  Google Scholar 

  41. Horch RE, Gerngross H, Lang W et al. (2005) Indications and safety aspects of vacuum-assisted wound closure. MMW Fortschr Med [Suppl 1] 147: 1–5

  42. Pelka R (1997) The economic situation of chronic wounds. Krankenpfl J 35: 338

    CAS  PubMed  Google Scholar 

  43. Holle G, Germann G, Sauerbier M et al. (2007) Vacuum-assisted closure therapy and wound coverage in soft tissue injury. Clinical use. Unfallchirurg 110: 289–300

    Article  CAS  PubMed  Google Scholar 

  44. Holle G, Riedel K, Gregory H von et al. (2007) Vacuum-assisted closure therapy. Current status and basic research. Unfallchirurg 110: 490–504

    Article  CAS  PubMed  Google Scholar 

  45. Philbeck TE (1999) The clinical and cost effectiveness of externally applied negative pressure wound therapy in the treatment of wounds in home healthcare medicare patients. Ostomy Wound Manage 45

  46. Nord D (2002) Überlegungen zur Wirtschaftlichkeit der Vakuumversiegelung von Wunden mit dem VAC-Therapiesystem. Niedergelassene Chirurg 6: 1–3

    Google Scholar 

  47. Engrav LH, Heimbach DM, Reus JL et al. (1983) Early excision and grafting vs. nonoperative treatment of burns of indeterminant depth: a randomized prospective study. J Trauma 23: 1001–1004

    Article  CAS  PubMed  Google Scholar 

  48. Freising C, Horch RE (2004) Clinical results of cultivated keratinocytes to treat burn injuries – a metaanalysis. In: Horch RE, Munster AM, Achauer BM (eds) Cultured human keratnocytes and tissue engineered skin subtitutes. Thieme – J.A. Barth, Heidelberg New York, pp 220–226

  49. Eldad A, Stern Z, Sover H et al. (1993) The cost of an extensive burn survival. Burns 19: 235–238

    Article  CAS  PubMed  Google Scholar 

  50. Drummond MF, Sculpher MJ, Torrance GW (2005) Methods for the Economic Evaluation of Health Care Programmes. 3 edn. Oxford Univ Press, Oxford

Download references

Interessenkonflikt

Der korrespondierende Autor weist auf folgende Beziehung/en hin: Für diese Arbeit wurden keinerlei Zuwendungen oder Unterstützungen durch die Industrie erhalten. Die Autoren wurden für Vorträge auf Kongressen durch Reisekostenübernahmen, Honorare für Vorträge u. a. in der Vergangenheit durch die Fa. KCI, Wiesbaden unterstützt; REH und ML erhalten Drittmittel von KCI USA für experimentelle Untersuchungen zu molekularen Wirkungsmechanismen der Vakuumtherapie

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to R.E. Horch.

Additional information

Herrn Prof. Dr. Dr. h.c. Werner Hohenberger zum 60. Geburtstag gewidmet.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Horch, R., Nord, D., Augustin, M. et al. Ökonomische Aspekte in der chirurgischen Wundbehandlung. Chirurg 79, 518–525 (2008). https://doi.org/10.1007/s00104-008-1500-3

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00104-008-1500-3

Schlüsselwörter

Keywords

Navigation