Summary
Four cases of acute Wernickes Encephalopathy in non-alcoholic, malnourished patients are described. In each case the administration of a glucose load precipitated a neurological crisis which was rapidly reversed by the administration of intravenous Thiamine. It is suggested that prophylactic Thiamine treatment therapy should be considered in the management of all malnourished patients.
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References
Blass, J. P., Gibon, G. E. 1977. New Eng. J. Med. 297, 1367.
Cravioto, H., Korein, J., Silberman, J. 1961. Archs. Neurol. 4, 510.
Drenick, E. J., Joven, C. B., Swendseid, M. E. 1966. New Eng. J. Med. 274, 1937.
Ebels, E. J. 1978. Lancet ii, 781.
Harper, C. J. 1979. J. Neurol. Neurosurg. Psychiat. 42, 226.
Nadel, A. M., Burger, P. C. 1976. J.A.M.A. 235, 2403.
Wallis, W. E., Willoughby, E., Baker, P. 1978. Lancet ii, 480.
Zaporin, Z. Z., Nuves, W. T., Powell, R. C. 1965. J. Nutr. 85, 287.
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Watson, A.J.S., Walker, J.F., Tomkin, G.H. et al. Acute Wernickes Encephalopathy precipitated by glucose loading. I.J.M.S. 150, 301–303 (1981). https://doi.org/10.1007/BF02938260
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DOI: https://doi.org/10.1007/BF02938260