Abstract
Astrovirus antibody was detected by immunofluorescence using infected primary human embryo kidney cultures as antigen. Of 87 Oxford children aged 0–10 years, only 7% in the 6 to 12-month-old group had antibody. The percentage of children having evidence of past infection rose progressively in the 1–4 age range and 75% of the 5 to 10-year-old group possessed astrovirus antibody. Fifty-four (77%) of a group of 70 young adults likewise had antibody.
Similar content being viewed by others
References
Appleton, H., Higgins, P.G.: Viruses and gastroenteritis in infants. Lancet1975 I, 1297
Kurtz, J.B., Lee, T.W., Craig, J.W., Reed, S.E.: Astrovirus infection in volunteers. In the press, 1978
Kurtz, J.B., Lee, T.W., Pickering, D.: Astrovirus associated gastroenteritis in a children's ward. J. Clin. Path.30, 948–52 (1977)
Lee, T.W., Kurtz, J.B.: Astroviruses detected by immunofluorescence. Lancet1977 II, 406
Madeley, C.R., Cosgrove, B.P.: Viruses in infantile gastroenteritis. Lancet1977a II, 124
Madeley, C.R., Cosgrove, B.P.: 28 nm particles in faeces in infantile gastroenteritis. Lancet1975b II, 451
Madeley, C.R., Cosgrove, B.P., Bell, E.J., Fallon, R.J.: Stool viruses in babies in Glasgow. J. Hyg. Camb.78, 261–273 (1977)
Snodgrass, D.R., Gray, E.W.: Detection and transmission of 30 nm virus particles (Astrovirus) in faeces of lambs with diarrhoea. Arch. Viol.55, 287–291 (1977)
Woode, G., Bridger, J.: Personal communication, 1977
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kurtz, J., Lee, T. Astrovirus gastroenteritis age distribution of antibody. Med Microbiol Immunol 166, 227–230 (1978). https://doi.org/10.1007/BF02121154
Issue Date:
DOI: https://doi.org/10.1007/BF02121154