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Inconsistent stimulation of plasma ACTH through corticotropin-releasing factor in a patient with central Cushing's disease due to pituitary adenoma

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Summary

Three uncommon findings were observed in a case of Cushing's disease due to macroadenoma: no suppression of plasma ACTH during an 8-mg dexamethasone test, a negative corticotropin-releasing factor test, and a normal X-ray of the sella turcica. Despite these findings, the diagnosis of pituitary was confirmed Cushing's syndrome by computerized tomography and a transphenoidal operation.

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Abbreviations

CRF:

corticotropin releasing factor

CD:

Cushing's disease

CS:

Cushing's syndrome

CT:

computerized tomography

GH:

growth hormone

FSH:

follicle-stimulating hormone

LH:

luteinizing hormone

LH-RH:

luteinizing hormone releasing hormone

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Rohrmoser, B., Lüdecke, D.K. & Scriba, P.C. Inconsistent stimulation of plasma ACTH through corticotropin-releasing factor in a patient with central Cushing's disease due to pituitary adenoma. Klin Wochenschr 63, 475–477 (1985). https://doi.org/10.1007/BF01731496

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  • DOI: https://doi.org/10.1007/BF01731496

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