Abstract
The purpose of this study was twofold: (1) to determine the incidence of intrahepatic hematoma after liver biopsy by the aspiration technique and (2) to compare the incidence of hematoma after biopsy with a needle of 1.6 mm vs 1.9 mm OD. Fifty-one patients were randomly assigned to be biopsied with the smaller needle and 46 with the larger. Hematomas, diagnosed by development of characteristic transient defects on liver scans done shortly after biopsy, occurred in two (4%) of those biopsied with the smaller needle and in none of those biopsied with the larger. This difference is not statistically significant. Neither patient who developed a hematoma had changes in vital signs, CBC, or serum alkaline phosphatase. One had a fivefold rise in SGOT; in the other, the SGOT remained normal. If these results are considered with those of other prospective trials of similar design, the overall incidence of intrahepatic hematoma after aspiration biopsy may be estimated to be 2.3% when needles of 1.6–2.0 mm (OD) are used. Many of these go undetected because, justifiably, scans are not routinely done shortly after biopsies.
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References
Bowden L, Kravitz S: Needle biopsy of the liver: A diagnostic aid in the treatment of cancer Cancer 6:1010–1020, 1953
Parker JG, Simon M, Zimetbaum M, et al: Needle liver biopsy in benign and malignant disease: Comparison of the Menghini and Vim-Silverman techniques. Am J Dig Dis 7:687–698, 1962
Zamcheck N, Klausenstock O: Liver biopsy II. The risk of needle biopsy. N Engl J Med 249:1062–1069, 1953
Edmondson HA, Schiff L: Needle biopsy of the liver.In Diseases of the Liver, 4th ed, L Schiff (ed) Philadelphia. JB Lippincott, 1975, pp 247–271
Thaler H: Über Vorteil und Risiko der Leberbiopsiemethode nach Menghini. Wien Klin Wochenschr 76:533–538, 1964
Lindner H: Grenzen und Gefahren der perkutanen Leberbiopsie mit der Menghini-Nadel: Erfahrungen bei 80,000 Leberbiopsien. Dtsch Med Wochenschr 92:1751–1757, 1967
Raines DR, Van Heertum RL, Johnson LF: Intrahepatic hematoma: A complication of percutaneous liver biopsy. A report on the incidence of post-biopsy scan defects. Gastroenterology 67:284–289, 1974
Conn H: Intrahepatic hematoma after liver biopsy. Gastroenterology 67:375–381, 1974 (editorial)
Knauer CM: Percutaneous biopsy of the liver as a procedure for outpatients. Gastroenterology 74:101–102, 1978
Perrault J, McGill DB, Ott JB, et al: Liver biopsy: Complications in 1000 inpatients and outpatients. Gastroenterology 74:103–106, 1978
Menghini G: One second biopsy of the liver-problems of its clinical application. N Engl J Med 283:582–585, 1970
Ozonoff M: Roentgenologic demonstration of intra-hepatic hematoma following liver biopsy. Am J Dig Dis 7:844–849, 1962
Johnson RA, Moro LD, Glasgow J: Intrahepatic hematoma following liver biopsy by the Menghini technic. Am J Gastroenterol 50:131–134, 1968
Beckert W: Central liver hematoma after a percutaneous biopsy of the liver. Z Aerztl Forbild (Jena) 65:36–38, 1971
Greenwald R, Chirput RD, Schiff ER:, Percutaneous aspiration liver biopsy using a large-caliber disposable needle. A preliminary report. Am J Dig Dis 22:1109–1114, 1977
Colton T: Statistics in Medicine. Boston, Little, Brown 1974, p 168
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Supported by research funds from U.S. Veterans Administration.
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Forssell, P.L., Bonkowsky, H.L., Anderson, P.B. et al. Intrahepatic hematoma after aspiration liver biopsy. Digest Dis Sci 26, 631–635 (1981). https://doi.org/10.1007/BF01367676
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DOI: https://doi.org/10.1007/BF01367676