Abstract
Ceramics, glasses, and glass-ceramics are increasingly being tested for use in the human body. These materials often have excellent chemical properties for biomedical use, but they are brittle and show fatigue. Careful analysis of their mechanical properties is needed to determine appropriate applications. Hydroxylapatite is emerging as the most promising bioceramic because it shows no foreign body reactions and bonds strongly to bone; if properly made without pores or second phases it has excellent fatigue resistance. Glass-ceramics containing hydroxylapatite crystals also show good promise for many applications. Different forms of these materials, such as dense, granular, mixed granular with plaster of Paris, and coatings on metals are being tested and have very good potential as bioceramics.
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References
K. de Groot (ed.), “Bioceramics of Calcium Phosphate” (CRC Press, Boca Raton, Florida, 1983).
J. S. Hanker and B. L. Giammara (eds), “Biomedical Materials and Devices” (Materials Research Society, Pittsburgh, PA, 1989).
J. S. Hanker and B. L. Giammara, Science 242 (1988) 885.
P. Ducheyne and G. W. Hastings (eds), “Metal and Ceramic Biomaterials”, Vols I and II (CRC Press, Boca Raton, Florida, 1984).
P. Ducheyne and J. E. Lemmons (eds), “Bioceramics”, Annals of the New York Academy of Sciences, Vol. 523 (New York Academy of Sciences, New York, 1988).
R. H. Doremus, in “Metal and Ceramic Biomaterials”, Vols I and II (CRC Press, Boca Raton, Florida, 1984) pp. 107–20.
D. W. Richerson, “Modern Ceramic Engineering” (Dekker, New York, 1982).
R. H. Doremus, “Glass Science” (Wiley, New York, 1973) p. 237–40.
R. W. Douglas and S. Frank, “A History of Glassmaking” (Foulis, Henley-on-Thames, UK, 1972).
F. V. Tooley (ed.), “Handbook of Glass Manufacture” (Books for Industry, New York, 1974).
M. Jarcho, C. H. Bolen, M. B. Thomas, J. Bobick, J. F. Kay and R. H. Doremus, J. Mater. Sci. 11 (1976) 2027.
C. E. Inglis, Trans. Inst. Naval Arch. 55 (1913) 219.
M. B. Thomas and R. H. Doremus, Amer. Ceram. Soc. Bull. 60 (1983) 258.
R. H. Doremus, J. Appl. Phys. 54 (1983) 193.
M. P. Delisle and R. H. Doremus, unpublished (1984).
T. Nakamura, T. Yamamuro, S. Higushi, T. Kokubo and S. Ito, J. Biomed. Mater. 19 (1985) 685.
R. H. Doremus, in “Treatise on Materials Science and Technology”, Vol. 22, edited by M. Tomozawa and R. H. Doremus (Academic Press, Orlando, FL, 1982) pp. 169–239.
M. B. Thomas, R. H. Doremus, J. Jarcho and R. L. Salsbury, J. Mater. Sci. 16 (1980) 891.
R. H. Doremus, Engng Fract. Mech. 13 (1980) 945.
R. J. Charles, J. Appl. Phys. 29 (1958) 1657.
R. H. Doremus, in “Strength of Inorganic Glass”, edited by C. R. Kurkjian (Plenum Press, New York, 1985) pp. 231–47.
K. de Groot (ed.), “Bioceramics of Calcium Phosphate” (CRC Press, Boca Raton, FL, 1983) p. 115ff.
G. L. De Lange, C. de Putter, K. De Groot and E. H. Burger, J. Dental Res. 68 (1989) 509.
N. Epstein, Smithsonian, December (1989) 98.
S. E. Brackett and M. G. Duncanson, “Biomedical Materials and Devices” (Materials Research Society, Pittsburgh, PA, 1989) pp. 579–88.
S. F. Hulbert, J. J. Klawitter and R. B. Leonard, in “Ceramics in Severe Environments”, edited by W. W. Kriegel and N. Palmour (Plenum Press, New York, 1971) p. 417.
“Encyclopedia of Chemical Technology”, Vol. 4 (Wiley, New York, 1978) p. 556ff.
R. O. Ritchie, R. H. Dauskardt, W. Yu and A. M. Brendzel, J. Biomed. Mater. Res. 24 (1990) 189.
L. L. Hench, R. J. M. Splinter, W. C. Allen and T. K. Greenlee, ibid. 2 (1971) 117.
E. Schepers, M. Declercq and P. Ducheyne, MS thesis, University of Florida, Gainesville, FL (1977) p. 178.
B. A. Blencke, H. Bromer and K. K. Deutscher, J. Biomed. Mater. 12 (1978) 307.
T. Kukubo, Y. Nagachima and M. Tashiro, YogyoKyokai-Shi 90 (1982) 151.
T. Kukuboi, S. Ito, M. Shigematsu, T. Nakjamura, T. Yamamuro and S. Higashi, Glastech. Ber. 56K (1983) 695.
T. Kukubo, S. Ito, M. Shigematsu, S. Sakka and T. Yamamuro, J. Mater. Sci. 20 (1985) 2001.
T. Kitsago, T. Yamamuro and T. Kukubo, J. Biomed. Mater. Res. 24 (1990) 259.
Idem, ibid. 24 (1990) 331.
T. Kukubo, S. Ito, M. Shigematsu, S. Sakka and T. Yamamuro, ibid. 22 (1987) 4067.
S. Hobo and T. Iwata, Quint. Int. 16 (1985) 135.
Idem, ibid. 16 (1985) 207.
Idem, ibid. 16 (1985) 451.
Idem, ibid. 16 (1985) 509.
P. J. Adair and G. D. Grossman, Int. J. Perio. Rest. Dent. 4 (1984) 32.
K. A. Malamet, J. Prosthet. Dent. 57 (1987) 674.
J. W. McLean and M. J. Kedge, Quint. Int. 18 (1987) 97.
D. G. Grossman, Dent. Clin. N. Amer. 29 (1985) 725.
G. De With, H. J. A. van Dijk, N. Hattu and K. Prijs, ibid. 16 (1981) 1592.
J. E. Burke, R. H. Doremus, W. B. Hillig and A. M. Trukalo, in “Ceramics in Severe Environments”, edited by W. W. Kriegel and H. Palmour (Plenum Press, New York, 1971) p. 435.
T. Kitsugi, T. Yamamuro, T. Nakamura, S. Higashi, Y. Kakutani, K. Hyakuna, S. Ito, T. Kokubu, M. Takagi and T. Shibuya, J. Biomed. Mater. Res. 20 (1986) 1295.
M. Jarcho, J. F. Kay, K. J. Gumar, H. P. Drobech and R. H. Doremus, J. Bioengng 1 (1976) 79.
J. F. Kay, PhD thesis, Rensselaer Polytechnic Institute, Troy, New York (1977).
B. M. Tracy and R. H. Doremus, J. Biomed. Mater. Res. 18 (1984) 719.
G. L. De Lange, C. de Putter and F. L. J. A. De Wijs, ibid. 24 (1990) 829.
B. J. Dalgleish and R. D. Rawlings, ibid. 15 (1981) 527.
M. Jarcho, R. L. Salsbury, M. B. Thomas and R. H. Doremus, J. Mater. Sci. 14 (1979) 142.
M. M. Walker, PhD thesis, Rensselaer Polytechnic Institute, Troy, New York (1984).
M. F. Zide, J. N. Kent and L. Machado, J. Oral Maxillofac. Surg. 45 (1987) 481.
M. el Deeb and M. Roszkowski, ibid. 46 (1988) 33.
M. el Deeb, ibid. 46 (1988) 758.
B. C. Terry, R. D. Baker, M. R. Tucker and J. S. Hanker, in “Biomedical Materials and Devices” (Materials Research Society, Pittsburgh, PA, 1989) p. 187, and other articles in this reference.
R. A. Carnevale, G. W. Greco, C. M. Bullard and J. S. Hunker, ibid.“, p. 257.
M. Uratsiyi, T. W. Bauer and S. J. Reger, ibid.in “, p. 199.
A. R. M. Wittkampf, J. Oral Maxillofac. Surg. 46 (1988) 1019.
C. P. A. T. Klein, H. B. M. van der Lubbe and K. de Groot, Biomater. 8 (1987) 308.
C. J. Damien, J. R. Parsons, J. J. Benedict and D. S. Weisman, J. Biomed. Mater. Res. 24 (1990) 639.
M. B. Habal, in “Biomedical Materials and Devices” (Materials Research Society, Pittsburgh, PA, 1989) p. 205.
G. de With and A. J. Corbijm, J. Mater. Sci. 24 (1989) 3411.
K. Hangst, J. Eitenmuller, R. Weltin and G. Peters, in “Biomedical Materials and Devices” (Materials Research Society, Pittsburgh, PA, 1989) p. 269.
D. P. Rivero, J. Fox, A. K. Skipper, R. M. Urban and J. O. Galente, J. Biomed. Mater. Res. 12 (1988) 191.
S. D. Cook, K. A. Thomas, J. F. Kay and M. Jarcho, Clin. Orthop. 230 (1988) 303.
P. Ducheyne and K. E. Healy, J. Biomed. Mater. Res. 22 (1988) 1137.
M. S. Block, J. N. Kent and J. F. Kay, J. Oral Maxillofac. Surg. 45 (1987) 601.
B. Koch, J. G. C. Wolke and K. de Groot, J. Biomed. Mater. Res. 24 (1990) 655.
K. de Groot, R. Geesink, C. P. A. J. Klein and P. Serekian, ibid. 21 (1987) 1375.
K. A. Thomas, J. F. Kay, S. D. Cook and M. Jarcho, ibid. 21 (1987) 1395.
K. Hayashi, N. Matsuguchi, K. Uenoyama, T. Kanemaru and Y. Sugioka, ibid. 23 (1989) 1247.
Y. Kabutani, T. Yamamuro, T. Nakamura and Y. Kotura, ibid. 23 (1989) 781.
K. de Groot, ibid. 23 (1989) 1367.
K. A. Thomas, ibid. 23 (1989) 1369.
J. Black, ibid. 23 (1989) 1243.
R. E. Holmes, R. W. Bucholtz and V. Mooney, J. Bone Joint Surg. 68A (1986) 904.
R. W. Bucholtz, J. Orthopedic Trauma 1 (1987) 260.
R. W. Bucholtz, A. Carlton and R. E. Holmes, Clin. Orth. Rel. Res. 240 (1989) 53.
C. A. van Blitterswijk, S. C. Hesseling, J. J. Grote, H. K. Koerten and K. de Groot, J. Biomed. Mater. Res. 24 (1990) 433.
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Doremus, R.H. Bioceramics. J Mater Sci 27, 285–297 (1992). https://doi.org/10.1007/BF00543915
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DOI: https://doi.org/10.1007/BF00543915