Skip to main content
Log in

Bioceramics

  • Review
  • Published:
Journal of Materials Science Aims and scope Submit manuscript

Abstract

Ceramics, glasses, and glass-ceramics are increasingly being tested for use in the human body. These materials often have excellent chemical properties for biomedical use, but they are brittle and show fatigue. Careful analysis of their mechanical properties is needed to determine appropriate applications. Hydroxylapatite is emerging as the most promising bioceramic because it shows no foreign body reactions and bonds strongly to bone; if properly made without pores or second phases it has excellent fatigue resistance. Glass-ceramics containing hydroxylapatite crystals also show good promise for many applications. Different forms of these materials, such as dense, granular, mixed granular with plaster of Paris, and coatings on metals are being tested and have very good potential as bioceramics.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. K. de Groot (ed.), “Bioceramics of Calcium Phosphate” (CRC Press, Boca Raton, Florida, 1983).

    Google Scholar 

  2. J. S. Hanker and B. L. Giammara (eds), “Biomedical Materials and Devices” (Materials Research Society, Pittsburgh, PA, 1989).

    Google Scholar 

  3. J. S. Hanker and B. L. Giammara, Science 242 (1988) 885.

    Google Scholar 

  4. P. Ducheyne and G. W. Hastings (eds), “Metal and Ceramic Biomaterials”, Vols I and II (CRC Press, Boca Raton, Florida, 1984).

    Google Scholar 

  5. P. Ducheyne and J. E. Lemmons (eds), “Bioceramics”, Annals of the New York Academy of Sciences, Vol. 523 (New York Academy of Sciences, New York, 1988).

    Google Scholar 

  6. R. H. Doremus, in “Metal and Ceramic Biomaterials”, Vols I and II (CRC Press, Boca Raton, Florida, 1984) pp. 107–20.

    Google Scholar 

  7. D. W. Richerson, “Modern Ceramic Engineering” (Dekker, New York, 1982).

    Google Scholar 

  8. R. H. Doremus, “Glass Science” (Wiley, New York, 1973) p. 237–40.

    Google Scholar 

  9. R. W. Douglas and S. Frank, “A History of Glassmaking” (Foulis, Henley-on-Thames, UK, 1972).

    Google Scholar 

  10. F. V. Tooley (ed.), “Handbook of Glass Manufacture” (Books for Industry, New York, 1974).

    Google Scholar 

  11. M. Jarcho, C. H. Bolen, M. B. Thomas, J. Bobick, J. F. Kay and R. H. Doremus, J. Mater. Sci. 11 (1976) 2027.

    Google Scholar 

  12. C. E. Inglis, Trans. Inst. Naval Arch. 55 (1913) 219.

    Google Scholar 

  13. M. B. Thomas and R. H. Doremus, Amer. Ceram. Soc. Bull. 60 (1983) 258.

    Google Scholar 

  14. R. H. Doremus, J. Appl. Phys. 54 (1983) 193.

    Google Scholar 

  15. M. P. Delisle and R. H. Doremus, unpublished (1984).

  16. T. Nakamura, T. Yamamuro, S. Higushi, T. Kokubo and S. Ito, J. Biomed. Mater. 19 (1985) 685.

    Google Scholar 

  17. R. H. Doremus, in “Treatise on Materials Science and Technology”, Vol. 22, edited by M. Tomozawa and R. H. Doremus (Academic Press, Orlando, FL, 1982) pp. 169–239.

    Google Scholar 

  18. M. B. Thomas, R. H. Doremus, J. Jarcho and R. L. Salsbury, J. Mater. Sci. 16 (1980) 891.

    Google Scholar 

  19. R. H. Doremus, Engng Fract. Mech. 13 (1980) 945.

    Google Scholar 

  20. R. J. Charles, J. Appl. Phys. 29 (1958) 1657.

    Google Scholar 

  21. R. H. Doremus, in “Strength of Inorganic Glass”, edited by C. R. Kurkjian (Plenum Press, New York, 1985) pp. 231–47.

    Google Scholar 

  22. K. de Groot (ed.), “Bioceramics of Calcium Phosphate” (CRC Press, Boca Raton, FL, 1983) p. 115ff.

    Google Scholar 

  23. G. L. De Lange, C. de Putter, K. De Groot and E. H. Burger, J. Dental Res. 68 (1989) 509.

    Google Scholar 

  24. N. Epstein, Smithsonian, December (1989) 98.

  25. S. E. Brackett and M. G. Duncanson, “Biomedical Materials and Devices” (Materials Research Society, Pittsburgh, PA, 1989) pp. 579–88.

    Google Scholar 

  26. S. F. Hulbert, J. J. Klawitter and R. B. Leonard, in “Ceramics in Severe Environments”, edited by W. W. Kriegel and N. Palmour (Plenum Press, New York, 1971) p. 417.

    Google Scholar 

  27. “Encyclopedia of Chemical Technology”, Vol. 4 (Wiley, New York, 1978) p. 556ff.

  28. R. O. Ritchie, R. H. Dauskardt, W. Yu and A. M. Brendzel, J. Biomed. Mater. Res. 24 (1990) 189.

    Google Scholar 

  29. L. L. Hench, R. J. M. Splinter, W. C. Allen and T. K. Greenlee, ibid. 2 (1971) 117.

    Google Scholar 

  30. E. Schepers, M. Declercq and P. Ducheyne, MS thesis, University of Florida, Gainesville, FL (1977) p. 178.

    Google Scholar 

  31. B. A. Blencke, H. Bromer and K. K. Deutscher, J. Biomed. Mater. 12 (1978) 307.

    Google Scholar 

  32. T. Kukubo, Y. Nagachima and M. Tashiro, YogyoKyokai-Shi 90 (1982) 151.

    Google Scholar 

  33. T. Kukuboi, S. Ito, M. Shigematsu, T. Nakjamura, T. Yamamuro and S. Higashi, Glastech. Ber. 56K (1983) 695.

    Google Scholar 

  34. T. Kukubo, S. Ito, M. Shigematsu, S. Sakka and T. Yamamuro, J. Mater. Sci. 20 (1985) 2001.

    Google Scholar 

  35. T. Kitsago, T. Yamamuro and T. Kukubo, J. Biomed. Mater. Res. 24 (1990) 259.

    Google Scholar 

  36. Idem, ibid. 24 (1990) 331.

    Google Scholar 

  37. T. Kukubo, S. Ito, M. Shigematsu, S. Sakka and T. Yamamuro, ibid. 22 (1987) 4067.

    Google Scholar 

  38. S. Hobo and T. Iwata, Quint. Int. 16 (1985) 135.

    Google Scholar 

  39. Idem, ibid. 16 (1985) 207.

    Google Scholar 

  40. Idem, ibid. 16 (1985) 451.

    Google Scholar 

  41. Idem, ibid. 16 (1985) 509.

    Google Scholar 

  42. P. J. Adair and G. D. Grossman, Int. J. Perio. Rest. Dent. 4 (1984) 32.

    Google Scholar 

  43. K. A. Malamet, J. Prosthet. Dent. 57 (1987) 674.

    Google Scholar 

  44. J. W. McLean and M. J. Kedge, Quint. Int. 18 (1987) 97.

    Google Scholar 

  45. D. G. Grossman, Dent. Clin. N. Amer. 29 (1985) 725.

    Google Scholar 

  46. G. De With, H. J. A. van Dijk, N. Hattu and K. Prijs, ibid. 16 (1981) 1592.

    Google Scholar 

  47. J. E. Burke, R. H. Doremus, W. B. Hillig and A. M. Trukalo, in “Ceramics in Severe Environments”, edited by W. W. Kriegel and H. Palmour (Plenum Press, New York, 1971) p. 435.

    Google Scholar 

  48. T. Kitsugi, T. Yamamuro, T. Nakamura, S. Higashi, Y. Kakutani, K. Hyakuna, S. Ito, T. Kokubu, M. Takagi and T. Shibuya, J. Biomed. Mater. Res. 20 (1986) 1295.

    Google Scholar 

  49. M. Jarcho, J. F. Kay, K. J. Gumar, H. P. Drobech and R. H. Doremus, J. Bioengng 1 (1976) 79.

    Google Scholar 

  50. J. F. Kay, PhD thesis, Rensselaer Polytechnic Institute, Troy, New York (1977).

    Google Scholar 

  51. B. M. Tracy and R. H. Doremus, J. Biomed. Mater. Res. 18 (1984) 719.

    Google Scholar 

  52. G. L. De Lange, C. de Putter and F. L. J. A. De Wijs, ibid. 24 (1990) 829.

    Google Scholar 

  53. B. J. Dalgleish and R. D. Rawlings, ibid. 15 (1981) 527.

    Google Scholar 

  54. M. Jarcho, R. L. Salsbury, M. B. Thomas and R. H. Doremus, J. Mater. Sci. 14 (1979) 142.

    Google Scholar 

  55. M. M. Walker, PhD thesis, Rensselaer Polytechnic Institute, Troy, New York (1984).

    Google Scholar 

  56. M. F. Zide, J. N. Kent and L. Machado, J. Oral Maxillofac. Surg. 45 (1987) 481.

    Google Scholar 

  57. M. el Deeb and M. Roszkowski, ibid. 46 (1988) 33.

    Google Scholar 

  58. M. el Deeb, ibid. 46 (1988) 758.

    Google Scholar 

  59. B. C. Terry, R. D. Baker, M. R. Tucker and J. S. Hanker, in “Biomedical Materials and Devices” (Materials Research Society, Pittsburgh, PA, 1989) p. 187, and other articles in this reference.

    Google Scholar 

  60. R. A. Carnevale, G. W. Greco, C. M. Bullard and J. S. Hunker, ibid.“, p. 257.

    Google Scholar 

  61. M. Uratsiyi, T. W. Bauer and S. J. Reger, ibid.in “, p. 199.

    Google Scholar 

  62. A. R. M. Wittkampf, J. Oral Maxillofac. Surg. 46 (1988) 1019.

    Google Scholar 

  63. C. P. A. T. Klein, H. B. M. van der Lubbe and K. de Groot, Biomater. 8 (1987) 308.

    Google Scholar 

  64. C. J. Damien, J. R. Parsons, J. J. Benedict and D. S. Weisman, J. Biomed. Mater. Res. 24 (1990) 639.

    Google Scholar 

  65. M. B. Habal, in “Biomedical Materials and Devices” (Materials Research Society, Pittsburgh, PA, 1989) p. 205.

    Google Scholar 

  66. G. de With and A. J. Corbijm, J. Mater. Sci. 24 (1989) 3411.

    Google Scholar 

  67. K. Hangst, J. Eitenmuller, R. Weltin and G. Peters, in “Biomedical Materials and Devices” (Materials Research Society, Pittsburgh, PA, 1989) p. 269.

    Google Scholar 

  68. D. P. Rivero, J. Fox, A. K. Skipper, R. M. Urban and J. O. Galente, J. Biomed. Mater. Res. 12 (1988) 191.

    Google Scholar 

  69. S. D. Cook, K. A. Thomas, J. F. Kay and M. Jarcho, Clin. Orthop. 230 (1988) 303.

    Google Scholar 

  70. P. Ducheyne and K. E. Healy, J. Biomed. Mater. Res. 22 (1988) 1137.

    Google Scholar 

  71. M. S. Block, J. N. Kent and J. F. Kay, J. Oral Maxillofac. Surg. 45 (1987) 601.

    Google Scholar 

  72. B. Koch, J. G. C. Wolke and K. de Groot, J. Biomed. Mater. Res. 24 (1990) 655.

    Google Scholar 

  73. K. de Groot, R. Geesink, C. P. A. J. Klein and P. Serekian, ibid. 21 (1987) 1375.

    Google Scholar 

  74. K. A. Thomas, J. F. Kay, S. D. Cook and M. Jarcho, ibid. 21 (1987) 1395.

    Google Scholar 

  75. K. Hayashi, N. Matsuguchi, K. Uenoyama, T. Kanemaru and Y. Sugioka, ibid. 23 (1989) 1247.

    Google Scholar 

  76. Y. Kabutani, T. Yamamuro, T. Nakamura and Y. Kotura, ibid. 23 (1989) 781.

    Google Scholar 

  77. K. de Groot, ibid. 23 (1989) 1367.

    Google Scholar 

  78. K. A. Thomas, ibid. 23 (1989) 1369.

    Google Scholar 

  79. J. Black, ibid. 23 (1989) 1243.

    Google Scholar 

  80. R. E. Holmes, R. W. Bucholtz and V. Mooney, J. Bone Joint Surg. 68A (1986) 904.

    Google Scholar 

  81. R. W. Bucholtz, J. Orthopedic Trauma 1 (1987) 260.

    Google Scholar 

  82. R. W. Bucholtz, A. Carlton and R. E. Holmes, Clin. Orth. Rel. Res. 240 (1989) 53.

    Google Scholar 

  83. C. A. van Blitterswijk, S. C. Hesseling, J. J. Grote, H. K. Koerten and K. de Groot, J. Biomed. Mater. Res. 24 (1990) 433.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Doremus, R.H. Bioceramics. J Mater Sci 27, 285–297 (1992). https://doi.org/10.1007/BF00543915

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00543915

Keywords

Navigation