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99mTc-Diethyl-HIDA

A contribution to the study of its structure

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Abstract

Sephadex column chromatography has shown that 99mTc-diethyl-HIDA consists of two clearly separable components. One of them seems to be an intermediate compound changing into the other, almost completely within two hours after reconstitution of the diethyl-HIDA (Solco HIDA) with pertechnetate. The two components could be the mono- and biscomplex of N-(2,6-diethyl-acetanilid)-imino diacetic acid with one atom of technetium. Animal experiments show that there is no important difference in the biological distribution in mice between the two components.

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Author notes

  1. Ugo Fonda

    Present address: Klinika Za Nuklearno Medicino-Klinični Center, Yu-61000, Ljubljana, Yugoslavia

Authors and Affiliations

  1. The Isotope-Pharmacy, 378 Frederikssundsvej, DK-2700, Brønshøj, Denmark

    Ugo Fonda & Bente Pedersen

Authors
  1. Ugo Fonda
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  2. Bente Pedersen
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Fonda, U., Pedersen, B. 99mTc-Diethyl-HIDA. Eur J Nucl Med 3, 87–89 (1978). https://doi.org/10.1007/BF00251629

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  • DOI: https://doi.org/10.1007/BF00251629

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