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Actually the swine has an active epidermal melanocytic system, a papillary and reticular dermis, and the hair cover is sparse. The animal tans, loves to lie in the sun, and will consume beer in large quantities. All of these traits are shared with man. Unfortunately, experiments with large numbers of these intelligent hedonists are prohibitively expensive.
Clark WH, Elder DE, Guerry D, Epstein MN, Greene MH, VanHorn M: A study of tumor progression: the precursor lesions of superficial spreading and nodular melanoma. Hum Pathol 15: 1147–1165, 1984
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Beginning in October 1965 with the group at the Massachusetts General Hospital, several groups (The Family Studies Section of the Environmental Epidemiology Branch of the National Cancer Institute, University of California at San Francisco, New York University, The University of Toronto, the Scottish Melanoma Group, The Melanoma Group at the Karolinska Institute, Temple University, and The Pigmented Lesion Group at the University of Pennsylvania) have studied the lesions of human melanocytic neoplasia. The photographic documentation of the serial lesions of tumor progression is quite similar from all of these studies
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The cover of the August 1, 1990 issue of Cancer Research honoring Dr. Bert Vogelstein for receiving the 1990 Bristol-Meyers Squlbb award has a superb diagram of tumor progression in colorectal carcinoma. One may precisely insert into the seven boxes of that diagram seven analogous melanocytic lesions. In addition established primary melanomas clearly show tumor progression within the primary melanoma, which forms at least one added step. As I read the literature on carcinoma of the colon, I see qualitative tumor progression steps within established colorectal carcinomas that are quite similar to those of melanoma
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Clark, W.H. Human cutaneous malignant melanoma as a model for cancer. Cancer Metast Rev 10, 83–88 (1991). https://doi.org/10.1007/BF00049406
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DOI: https://doi.org/10.1007/BF00049406