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  • © 2020

Bioactive Natural products in Drug Discovery

  • Explores bioactive natural products derived from medicinal plants
  • Describes recent advances in drug discovery from natural sources to treat human diseases
  • Summarizes the current strategies employed to discover new natural products using recent advances in genomics and fermentation
  • Reviews important biotechnological applications of natural products

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Table of contents (26 chapters)

  1. Front Matter

    Pages i-xii
  2. Plants Natural Products: Fountainheads for Drug Discovery and Development

    1. Front Matter

      Pages 1-1
    2. The Artemisia Genus: Panacea to Several Maladies

      • Bhupendra Koul, Taslimahemad Khatri
      Pages 3-95
    3. Bacopa monnieri: The Neuroprotective Elixir from the East—Phytochemistry, Pharmacology, and Biotechnological Improvement

      • Samapika Nandy, Anuradha Mukherjee, Devendra Kumar Pandey, Abhijit Dey
      Pages 97-126
    4. Current Knowledge of Cinnamomum Species: A Review on the Bioactive Components, Pharmacological Properties, Analytical and Biotechnological Studies

      • Devendra Kumar Pandey, Ronni Chaudhary, Abhijit Dey, Samapika Nandy, R. M. Banik, Tabarak Malik et al.
      Pages 127-164
    5. Swertia spp.: A Potential Source of High-Value Bioactive Components, Pharmacology, and Analytical Techniques

      • Prabhjot Kaur, Devendra Kumar Pandey, Abhijit Dey, Padmanabh Dwivedi, Tabarak Malik, R. C. Gupta
      Pages 165-213
  3. Plant Derived Natural Products as Leads for Drug Discovery

    1. Front Matter

      Pages 243-243
    2. Plant-Derived Quinones as a Source of Antibacterial and Anticancer Agents

      • Surbhi Goel, Preeti Singh Parihar, Vineet Meshram
      Pages 245-279
    3. CQDs Derived from Natural Sources: Excellent Bioimaging Agents

      • Ranjana Singh, Jyoti Goutam, Ranjan K. Singh
      Pages 303-311
  4. Microbial Natural Products: A Quintessential Source for Drug Discovery and Development

    1. Front Matter

      Pages 313-313
    2. Microbial Natural Products: Recent Insights into Novel Applications

      • Rajnish Kumar Verma, Amita Sharma
      Pages 315-333
    3. Metabolites of Fluorescent Pseudomonads and Their Antimicrobial and Anticancer Potentials

      • Kranti Tanguturu, Moumita Mondal, Ankit Banik, Gurusamy Raman, Natarajan Sakthivel
      Pages 355-377
    4. Ganoderma: A Propitious Medicinal Poroid Mushroom

      • Ranjeet Singh, Avneet Pal Singh, Gurpaul Singh Dhingra, Richa Shri
      Pages 379-410
    5. Pharmaceutically Important Metabolites from Marine Fungi

      • Vijayalakshmi Selvakumar, Satyender Singh, Karthik Kannan, Panneerselvam Annamalai
      Pages 411-425
    6. Endophytic Fungi: A Treasure Trove of Novel Bioactive Compounds

      • Mahiti Gupta, Kamlesh Kumar Shukla
      Pages 427-449
    7. Novel Products from Microalgae

      • G. Subashini, S. Bhuvaneswari
      Pages 451-465
    8. Lactic Acid Production and Its Application in Pharmaceuticals

      • Ajay Kumar, Joginder Singh, Chinnappan Baskar
      Pages 467-484

About this book

This book highlights different natural products that are derived from the plants and microbes that have shown potential as the lead compounds against infectious diseases and cancer. Natural products represent an untapped source of strikingly diverse chemotypes with novel mechanisms of action and the potential to serve as anticancer and anti-infective agents.

The book discusses a range of biotechnologically valuable bioactive compounds and secondary metabolites that have been derived from plant and microorganisms from various ecological niches. It also reviews the latest developments in the field of genomics, bioinformatics and industrial fermentation for harnessing the microbial products for commercial applications. In turn, the book’s closing section reviews important biotechnological applications of various natural products. Combining the expertise of specialists in this field, the book’s goal is to promote the further investigation of natural sources for the development of standardized, safe and effective therapies.

Editors and Affiliations

  • Department of Microbiology, Lovely Professional University, Phagwara, India

    Joginder Singh

  • Department of Plant Pathology and Weed Research, Agricultural Research Organization, The Volcani Centre, Rishon Lezion, Israel

    Vineet Meshram

  • Department of Biotechnology, Lovely Professional University, Phagwara, India

    Mahiti Gupta

About the editors

Dr. Joginder Singh is presently working as a Professor at the Department of Microbiology, Lovely Professional University, Punjab, India. His training and research experience prepared him to work with microbial consortium formulation and study its ecology. His particular areas of competence include planning and execution of R&D facilities at scientist level. He is an active member of various scientific societies and organizations, including Indian Science Congress Association, the Association of Microbiologists of India, K. K. Nanda Foundation for Advancement of Plant Sciences, Indian Society of Salinity Research Scientists, Indian Society for Radiation Biology, Hong Kong Chemical, Biological & Environmental Engineering Society, and European Federation of Biotechnology. The Academy of Plant Sciences, India (2016) conferred him certificate of excellence in the field of Microbial Technology. He serves as a reviewer for many prestigious journals and has published morethan 60 research and review articles in peer-reviewed journals, edited 4 books, and authored/co-authored 25 book chapters.

Dr. Vineet Meshram is currently working as a Visiting Scientist at the Department of Plant Pathology and Weed Research, the Volcani Centre, Agriculture Research Organization, Israel. He previously served as an Assistant Professor at the Department of Biochemistry, DAV University, India (2016-17). He has over 10 years of research experience in microbial secondary metabolites, microbial biochemistry, biological control, mycology, and drug discovery. His research work has resulted in over 15 referred journal articles, 21 abstracts and, three book chapters. He is also a founder member of the International Society for Fungal Conservation. In recognition of his contributions, the Mycological Society of India (2012) and European Mycological Society (2015) selected him for a Young Scientist Award. Recently, he has been awarded Karsons's award (2019) by The Ministry of Agriculture, Agricultural Research Organization, Israel, for his studies on plant-microbe interactions.

Dr. Mahiti Gupta is an Assistant Professor at the Department of Biotechnology, Lovely Professional University, India. Her research interests are in natural products and drug discovery, enzyme inhibitors, protein purification, and characterization. She is currently working on endophytes and Stevia. She has been honored with a UGC Meritorious Fellowship and a Young Scientist Award. She has published seven research articles in peer-reviewed international and national journals and has authored and co-authored several book chapters. She is a member of numerous scientific societies, including the Indian Science Congress.

Bibliographic Information

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access