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  • © 2018

Circular RNAs

Biogenesis and Functions

Editors:

  • Introduces an overview of the rapidly advancing field of circular RNAs up to now
  • Covers a wide range of circular RNAs research
  • Provides future prospects of the research

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1087)

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Table of contents (28 chapters)

  1. Front Matter

    Pages i-vii
  2. Overview

    1. Front Matter

      Pages 1-1
    2. An Overview of Circular RNAs

      • Rajendra Awasthi, Anurag Kumar Singh, Gaurav Mishra, Anand Maurya, Dinesh Kumar Chellappan, Gaurav Gupta et al.
      Pages 3-14
  3. Bioinformatics for Circular RNAs

    1. Front Matter

      Pages 15-15
    2. RNA sequencing and Prediction Tools for Circular RNAs Analysis

      • Elena López-Jiménez, Ana M. Rojas, Eduardo Andrés-León
      Pages 17-33
    3. Online Databases and Circular RNAs

      • Seyed Hamid Aghaee-Bakhtiari
      Pages 35-38
  4. Biogenesis of Circular RNAs

    1. Front Matter

      Pages 39-39
    2. Circular RNA Splicing

      • Nicole Eger, Laura Schoppe, Susanne Schuster, Ulrich Laufs, Jes-Niels Boeckel
      Pages 41-52
  5. Molecular Mechanisms and Gene Regulation of Circular RNAs

    1. Front Matter

      Pages 65-65
    2. Circular RNAs Act as miRNA Sponges

      • Amaresh Chandra Panda
      Pages 67-79
    3. Regulation of Transcription by Circular RNAs

      • Rumela Bose, Rupasri Ain
      Pages 81-94
    4. Functional Analysis of Circular RNAs

      • Shanmugapriya, Hisham Alkatib Huda, Soundararajan Vijayarathna, Chern Ein Oon, Yeng Chen, Jagat R. Kanwar et al.
      Pages 95-105
  6. Circular RNAs as Potential Disease Biomarkers

    1. Front Matter

      Pages 107-107
    2. Circular RNA in Exosomes

      • Daniele Fanale, Simona Taverna, Antonio Russo, Viviana Bazan
      Pages 109-117
    3. Circular RNAs in Blood

      • Angela Vea, Vicenta Llorente-Cortes, David de Gonzalo-Calvo
      Pages 119-130
    4. Circular RNA in Saliva

      • Farinaz Jafari Ghods
      Pages 131-139
    5. Emerging Role of Circular RNAs as Potential Biomarkers for the Diagnosis of Human Diseases

      • Rupal Ojha, Raj Nandani, Nina Chatterjee, Vijay Kumar Prajapati
      Pages 141-157
    6. Circular RNAs as Novel Biomarkers for Cardiovascular Diseases

      • Qiulian Zhou, Zhongrong Zhang, Yihua Bei, Guoping Li, Tianhui Wang
      Pages 159-170
    7. Circular RNAs as Biomarkers for Cancer

      • Lu Xia, Meiyi Song, Mengxue Sun, Fei Wang, Changqing Yang
      Pages 171-187

About this book

This book provides an essential overview of the rapidly advancing field of circular RNAs – newly discovered RNAs that are generated by back-splicing precursor mRNA and perform regulatory functions in many biological processes. Although many aspects of circular RNAs’ biology and mechanisms of gene regulation remain unclear, they have been found to be abundant, evolutionally conserved, and stable in cells; further, they have numerous potential functions. The book consists of eight parts:1) An overview of circular RNAs, 2) Bioinformatics for circular RNAs, 3) Biogenesis of circular RNAs, 4) Molecular mechanisms and gene regulation of circular RNAs, 5) Circular RNAs as potential disease biomarkers, 6) Circular RNAs and human diseases, 7) Circular RNAs in Plants and in Archaea, and 8) Future prospects. Given its focus, the book will be especially useful for researchers and students in the fields of biochemistry, molecular biology, cell biology, and medicine.


Editors and Affiliations

  • School of Life Science, Institute of Cardiovascular Sciences, Shanghai University, Shanghai, China

    Junjie Xiao

About the editor

Dr. Junjie Xiao is Principal Investigator and Professor at Regeneration and Ageing Lab in Shanghai University, Shanghai, China.

Bibliographic Information

  • Book Title: Circular RNAs

  • Book Subtitle: Biogenesis and Functions

  • Editors: Junjie Xiao

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-981-13-1426-1

  • Publisher: Springer Singapore

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Singapore Pte Ltd. 2018

  • Hardcover ISBN: 978-981-13-1425-4Published: 11 October 2018

  • Softcover ISBN: 978-981-13-4632-3Published: 29 December 2018

  • eBook ISBN: 978-981-13-1426-1Published: 27 September 2018

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: VII, 370

  • Number of Illustrations: 6 b/w illustrations, 35 illustrations in colour

  • Topics: Human Genetics, Biochemistry, general, Cell Biology

Buy it now

Buying options

eBook USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access