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Hormones and the Brain

  • Book
  • © 1980

Overview

Authors:
  1. David Wied

    1. Rudolf Magnus Instituut voor Farmacologie, Medische Faculteit, Rijksuniversiteit Utrecht, Utrecht, The Netherlands

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  2. Pieter A. Keep

    1. International Health Foundation, Genèva, Switzerland

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    You can also search for this author in PubMed   Google Scholar

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Table of contents (27 chapters)

  1. Front Matter

    Pages i-xiv
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  2. Receptors and peptidergic pathways in the brain

    1. Front Matter

      Pages 1-1
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    2. Hormone receptors in the brain

      • R. E. Whalen
      Pages 3-10

    3. Toward an understanding of the multiplicity of glucocorticoid actions on brain function and behaviour

      • B. S. McEwen, D. J. Micco
      Pages 11-28

    4. Effects of sex steroids on cell membrane excitability: a new concept for the action of steroids on the brain

      • B. Dufy, J. D. Vincent
      Pages 29-41

    5. Changing concepts about neuroregulation: neurotransmitters and neuromodulators

      • G. R. Elliott, J. D. Barchas
      Pages 43-52

    6. Cholecystokinin and bradykinin: putative peptide neurotransmitters

      • R. B. Innis, S. H. Snyder
      Pages 53-62

    7. Growth hormone dependent polypeptides and the brain

      • V. R. Sara, K. Hall, L. Wetterberg
      Pages 63-72

    8. On the multiplicity of active substances in single neurons: β-endorphin and α-melanocyte stimulating hormone as a model system

      • S. J. Watson, H. Akil
      Pages 73-86

    9. Neurohypophysial hormones and their distribution in the brain

      • D. F. Swaab
      Pages 87-100

  3. Hormones and behaviour

    1. Front Matter

      Pages 101-101
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    2. Peptides and adaptive behaviour

      • D. de Wied
      Pages 103-113

    3. Structure and behavioural activity of peptides related to corticotrophin and lipotrophin

      • H. M. Greven, D. de Wied
      Pages 115-127

    4. Effects of neuropeptides on adaptive autonomic processes

      • B. Bohus
      Pages 129-139

    5. Endorphins and schizophrenia

      • H. M. Van Praag, W. M. A. Verhoeven
      Pages 141-153

    6. Effects of MIF-I and TRH on the brain

      • R. H. Ehrensing, A. J. Kastin
      Pages 155-165

    7. Neurohypophysial hormones and addiction

      • J. M. van Ree
      Pages 167-173

    8. Androgens and behaviour

      • R. M. Rose
      Pages 175-187

    9. Female hormones and brain function

      • H. Kopera
      Pages 189-203

    10. Hormones and sexual impotence

      • J. J. Legros, P. Chiodera, C. Mormont, J. Servais, P. Franchimont
      Pages 205-217
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Keywords

About this book

During the last decade it has become evident that the brain is an important target for hormones. Although it has been discovered only recently that the brain contains numerous peptide hormones, the role of pituitary and hypo­ thalamic hormones in brain activity has been the subject of basic studies for quite some time. Peptide hormones are involved in mental performance. pain perception, food and water metabolism. sleep. sexual behaviour and nursing behaviour, and disturbances in the hormonal climate of the brain may be associated with psychopathology. cognitive disturbances and. possibly. addic­ tion. The clinical influence of neurohypophysial hormones and their frag­ ments is studied today on learning and memory. on inadequate behaviour and addiction, in Parkinson's disease. Lesch-Nyhan syndrome. depression and schizophrenia. Fragments of adrenocorticotrophin have been shown to affect motivation, concentration and attention. and neuropeptides derived from ~-lipotrophin are probably involved in psychopathology. Thyrotrophin­ releasing hormone has been implicated in depression. and lutein-releasing hormone in sexual disturbances. In spite of the impressive experimental data; clinical results to date have been controversial and. to some extent. anecdotal. In some cases they have been exciting. and in others disappointing. It was against this background that the International Health Foundation decided to organize and sponsor their workshop on 'The brain as an endo­ crine target organ in health and disease' at which the papers appearing in this book were presented.

Authors and Affiliations

  • Rudolf Magnus Instituut voor Farmacologie, Medische Faculteit, Rijksuniversiteit Utrecht, Utrecht, The Netherlands

    David Wied

  • International Health Foundation, Genèva, Switzerland

    Pieter A. Keep

Bibliographic Information

  • Book Title: Hormones and the Brain

  • Authors: David Wied, Pieter A. Keep

  • DOI: https://doi.org/10.1007/978-94-009-8709-8

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: MTP Press Limited 1980

  • Softcover ISBN: 978-94-009-8711-1Published: 13 October 2011

  • eBook ISBN: 978-94-009-8709-8Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: 337

  • Topics: Internal Medicine

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