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  • © 2014

Toxic Effects of Mercury

Authors:

  • The book has relevance in present times due to a large population exposed to mercury toxicity

  • The book gives a detailed and comprehensive account of neurological effects of mercury poisoning

  • The book also explores the defense mechanism of the body in response to mercury toxicity

  • This study focused primarily on two antioxidants: 1) Vitamin- E and 2) Acetyl-L-Carnitine and their intervention in methylmercury poisoning by improving the mobilization and excretion of this metal

  • Includes supplementary material: sn.pub/extras

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Table of contents (32 chapters)

  1. Front Matter

    Pages i-xxv
  2. History of Mercury Toxicology

    1. Front Matter

      Pages 1-1
    2. Occurrence and Properties

      • Shabnum Nabi
      Pages 3-7
    3. Estimated Applications

      • Shabnum Nabi
      Pages 9-14
    4. Distribution, Metabolism, and Excretion

      • Shabnum Nabi
      Pages 15-18
    5. Toxic Effects and Remedy

      • Shabnum Nabi
      Pages 19-27
    6. Antioxidant Drugs Mitigating Toxicity

      • Shabnum Nabi
      Pages 29-35
    7. Mercury and Cognition

      • Shabnum Nabi
      Pages 37-47
  3. Review of Literature

    1. Front Matter

      Pages 49-49
    2. Exposure, Sources, and Intoxication

      • Shabnum Nabi
      Pages 51-63
    3. Methylmercury and Oxidative Stress

      • Shabnum Nabi
      Pages 65-70
  4. Toxicity Evaluation Methodology

    1. Front Matter

      Pages 71-71
    2. Materials and Analytical Procedures

      • Shabnum Nabi
      Pages 73-75
    3. Biochemical Estimation Techniques

      • Shabnum Nabi
      Pages 77-83
    4. Neurobehavioral Assessment Models

      • Shabnum Nabi
      Pages 85-91
  5. Free Radical Stress

    1. Front Matter

      Pages 93-93
    2. Results and Conclusions

      • Shabnum Nabi
      Pages 105-113
  6. Toxic Responses of Antioxidant Defense System

    1. Front Matter

      Pages 115-115

About this book

Mercury is widespread in our environment. Methylmercury, an organic form of mercury, can accumulate in the aquatic food chain and lead to high concentrations in predatory fish. When consumed by humans, contaminated fish represent a public health risk. Toxic Effects of Mercury intends to facilitate among its readers the understanding of the importance of mercury pollution in the environment and the health consequences associated with exposure to this metal. The knowledge on methylmercury (MeHg) toxicity collected over the years is undoubtedly robust creating an impression all that is to be learnt about this metal has already been accomplished. However, in large measure, past knowledge has merely laid the ground for interesting questions that have yet to be fully addressed and concepts have yet to be deciphered. One of my major goals was to make a valiant attempt to include state-of-the-art information on the mechanisms of mercury toxicity, describing its effects on cultured cellular systems as well as in whole living organisms, starting from the lessons learned from the tragic events in Minamata Bay, Japan. A special focus of the book is on the neurotoxic effects of MeHg. An understanding at the cellular level is necessary to gather information on the structural and functional alterations induced by MeHg and how they possibly become unmasked and evident at the behavioral level, 32 chapters of the book have been organised having these considerations in mind.

This book will provide state-of-the-art information to the graduate students training in toxicology, risk assessors, researchers and medical providers at large. It is aimed to bring the readers updated information on contemporary issues associated with exposure to methylmercury, from its effects on stem cells and neurons to population studies. It is a valuable resource for individuals interested in the public health effects and regulation of mercury. The report provides an excellent example of the implications of decisions in the risk assessment process for a larger audience and is written with the hope that the information will provide better understanding of the mercury problems which confront us.

Authors and Affiliations

  • Interdisciplinary Brain Research Centre (IBRC), Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India

    Shabnum Nabi

About the author

Dr. Shabnum has obtained her Ph.D. degree in Zoology (Cytogenetics) in 2012. The prime focus of her research has been Neurotoxicity, Genotoxicity and Neurobehavioral toxicity. She is the author of several papers published in reputed and peer-reviewed journals. Besides having National and International conferences to her credit, she is the member of Zoological Society of India. She has participated as a young scientist in a congregation of Nobel Prize Winners at IIIT Allahabad. She has also availed a Research Fellowship (J.R.F.) from University Grants Commission (U.G.C.), New Delhi.

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access