Biochemical Engineering for 2001

1. Front Matter

   Pages I-XXIII

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2. Overview

   1. Front Matter

      Pages 1-1

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   2. Biochemical Engineering — Past, Present, and Future

      • Arthur E. Humphrey

      Pages 3-7

   3. Strategic Planning and New Directions in Biochemical Engineering

      • Peter L. Rogers

      Pages 8-13

   4. New Biocatalytic Functions of Microorganisms and Their Industrial Applications

      • Hideaki Yamada

      Pages 14-17

3. Gene and Protein Engineering

   1. Front Matter

      Pages 19-19

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   2. Development of a Bacillus brevis Host-Vector System for Efficient Heterologous Protein Production and Its Application to Protein Engineering

      • Hideo Yamagata

      Pages 21-26

   3. Chimeric Receptor Made from IgM and EGFR that Induces Phosphorylation Upon Binding with Antigen

      • Hiroshi Ueda, Masako Kikuchi, Shintaro Yagi, Hajime Nishimura

      Pages 27-30

   4. Molecular Cloning of Feline Interferon cDNA by Direct Expression and Its Mass Production Using Silkworm

      • Naoko Nakamura, Tetsuo Sudo, Yoshizumi Ueda, Tohru Sakurai, Susumu Matsuda, Akira Yanai

      Pages 31-34

   5. Expression of Human Calcitonin in Escherichia coli

      • Toshihiko Kaminuma, Toshii Iida, Masahiro Tajima, Mitsuo Yanagi, Shoji Fukushima

      Pages 35-38

   6. Control of Gene Expression and Overproduction of Useful Heterologous Protein by Using an On-Line Sensor

      • Shinji Iijima, Young Soo Park, Takeshi Kobayashi

      Pages 39-42

   7. Expression and Secretion of Cloned Proteins in Recombinant Saccharomyces cerevisiae

      • Jin-Ho Seo, Hyung-Guen Lim, Mark Marten, Anant Patkar, Marvin Peterson

      Pages 43-46

   8. Plasmid Loss Probability in Escherichia coli as a Function of the Growth Rate of Plasmid-Bearing Cells. I: Variation During Continuous Cultures

      • Nabil Nancib, Ridha Mosrati, Joseph Boudrant

      Pages 47-49

   9. Plasmid Loss Probability in Escherichia coli as a Function of the Growth Rate of Plasmid-Bearing Cells. II: Modelling for Continuous Cultures

      • Ridha Mosrati, Nabil Nancib, Joseph Boudrant

      Pages 50-52

   10. Cloning and Expression of the Xylose (Glucose) Isomerase Gene from the Thermophile Thermus thermophilus HB8

       • Koen Dekker, Ayumu Sugiura, Hideo Yamagata, Kenji Sakaguchi, Shigezo Udaka

       Pages 53-55

   11. Mutagenesis Studies on the Amino Acid Residues Involved in an Iron-Binding Domain and a Catalytic Site of Human 5-Lipoxygenase

       • Satoshi Ishii, Masato Noguchi, Takashi Matsumoto, Masana Noma

       Pages 56-58

   12. Technology of Production of Recombinant Prourokinase

       • Dmitry V. Sakharov, Alexander J. Shevelev, Ljubov M. Metlitskaya, Maria V. Lapina, Sergey P. Domogatsky

       Pages 59-61

   13. High Level Expression and Secretion of Biologically Active Leech Hirudin Variant 1 (HV1) by Escherichia coli

       • Satoru Misawa, Hideyuki Furuya, Hitoshi Matsuda, Shin-Ichiro Abe, Hideya Hayashi

       Pages 62-64

   14. Transfer of Isolated Nuclei of Saccharomyces cerevisiae into Anucleated Protoplasts of Nectaromyces species

       • Weitie Lin, Ruhua Yao, Lianjiu Chen

       Pages 65-67

4. Enzyme Engineering

   1. Front Matter

      Pages 69-69

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Biochemical engineering forms a bridge between fundamental biochemical research and large scale biotechnology processes. It covers genetic and protein engineering, cell culture, bioprocess and reactor design, separation and modelling. Research work in biochemical engineering is an investment in the future, when conventional resources will have to be replaced with renewable ones. In this book the papers presented at the Asia-Pacific Biochemical Engineering Conference (Yokohama, Japan 1992) are collected. This collection is unique in its wide coverage of topics and it gives an overview of the current trends of research in an important area.

• biochemical engineering
• biotechnology
• cell culture
• chemical engineering
• protein
• protein engineering

• Department of Chemical Engineering, Faculty of Engineering, The University of Tokyo, Bunkyo-ku, Tokyo 113, Japan

  Shintaro Furusaki

• The Institute of Physical and Chemical Research, Wako-shi, Saitama, Japan

  Isao Endo

• Department of Food Science and Technology, Faculty of Agriculture, Kyoto University, Kitashirakawa Oiwake-cho, Sakyo-ku, Kyoto, Japan

  Ryuichi Matsuno

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