Postnatal Development of the Human Hippocampal Formation

1. Front Matter

   Pages i-xvi

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2. Introduction

   • Ricardo Insausti, Sandra Cebada-Sánchez, Pilar Marcos

   Pages 1-3

3. Materials and Methods

   • Ricardo Insausti, Sandra Cebada-Sánchez, Pilar Marcos

   Pages 5-7

4. General Organization of the HF Fields Related to Macroscopic Anatomy

   • Ricardo Insausti, Sandra Cebada-Sánchez, Pilar Marcos

   Pages 9-26

5. Microscopic Anatomy of HF Fields

   • Ricardo Insausti, Sandra Cebada-Sánchez, Pilar Marcos

   Pages 27-60

6. Correlation Between Anatomy and MRI

   • Ricardo Insausti, Sandra Cebada-Sánchez, Pilar Marcos

   Pages 61-69

7. Functional and Pathological Aspects of the Maturation of the Human Hippocampal Formation

   • Ricardo Insausti, Sandra Cebada-Sánchez, Pilar Marcos

   Pages 71-78

8. Back Matter

   Pages 79-89

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Ume Eder Bat (A beautiful child) (popular song from Basque folklore) The aim of this monograph is to introduce the postnatal development of morphological features that are relevant to readers interested in the neurobiology and pathology of the hippocampal formation in terms of the complex phenomena that underlie the progressive anatomical and functional maturation of this brain region. This review focuses on the morphological aspects, while more detailed basic phenomena associated with neuronal maturation—which are undoubtedly also of great interest—are only marginally referred to, although a selection of behavioral and clinical aspects will also be briefly addressed in an attempt to illustrate real situations in different clinical specialties. The creation of this monograph is justified by the increasing importance and growing awareness shown in recent years of neurodevelopmental disorders in children. This awareness is leading to increasing refinement in clinical exami- tions of patients that may suffer from different neurodevelopment-related diseases, such as autism, epilepsy, memory disorders, etc. To the best of our knowledge, this work is the first comprehensive description of the postnatal changes in the hip- campal formation in its different constituent fields. Given the growing sensitivity and accuracy of neuroradiological examinations, particularly MRI, we also sought to offer a glimpse at the MRI aspects related to the development of the hippocampal formation in the human infant.

• Neurobiology
• anatomy
• attention deficit
• autobiographical memory
• bipolar disorder
• development
• epilepsy
• hyperactivity disorder
• memory maturation

From the reviews:

“Number 206 in the Series Advances in Anatomy Embryology and Cell Biology, the authors describe the early development of the hippocampus, a CNS region important for the normal development of children. Of interest to anatomists, embryologists and developmental neurologists.” (Pediatric Endocrinology Reviews, Vol. 7 (4), June, 2010)

• CRIB, Universidad Castilla-La Mancha, Albacete, Spain

  Ricardo Insausti, Sandra Cebada-Sánchez, Pilar Marcos

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