Overview
- The only book to develop explicit procedures for evaluating evidence of mechanisms
- Contains a philosophical justification of these procedures
- Extends and improves the tools available to Evidence-Based Medicine (EBM)
Part of the book series: SpringerBriefs in Philosophy (BRIEFSPHILOSOPH)
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Table of contents (10 chapters)
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Front Matter
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Why Consider Mechanisms?
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Front Matter
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Particular Applications
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Front Matter
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Keywords
- Evidence-based medicine
- Mechanisms in medicine
- Evaluating evidence
- Medical methodology
- Evidence hierarchy
- Philosophy of medicine
- Mechanisms in literature
- Mechanism hypothesis
- Hypothesize a mechanism
- evidence of mechanisms
- Assessing exposures
- evidence and status of claim.
- Humanities Research
- Evidence-Based Medicine (EBM)
- Molecular epidemiology
- ebmplus.org
- analogous epistemic theory
- external validity
- effects of environmental exposures
- Open access
About this book
This book is open access under a CC BY license.
This book is the first to develop explicit methods for evaluating evidence of mechanisms in the field of medicine. It explains why it can be important to make this evidence explicit, and describes how to take such evidence into account in the evidence appraisal process. In addition, it develops procedures for seeking evidence of mechanisms, for evaluating evidence of mechanisms, and for combining this evaluation with evidence of association in order to yield an overall assessment of effectiveness.
Evidence-based medicine seeks to achieve improved health outcomes by making evidence explicit and by developing explicit methods for evaluating it. To date, evidence-based medicine has largely focused on evidence of association produced by clinical studies. As such, it has tended to overlook evidence of pathophysiological mechanisms and evidence of the mechanisms of action of interventions.
The bookoffers a useful guide for all those whose work involves evaluating evidence in the health sciences, including those who need to determine the effectiveness of health interventions and those who need to ascertain the effects of environmental exposures.
Authors and Affiliations
About the authors
The authors of this book are members of EBM+ (ebmplus.org), a network of researchers investigating the role of evidence of mechanisms in the health sciences. During the writing of this book, Parkkinen, Wallmann, Wilde and Williamson were based at the Centre for Reasoning, University of Kent; Clarke, Illari and Norell at the Department of Science and Technology Studies, UCL; Kelly at the Department of Public Health and Primary Care, University of Cambridge; Russo at the Department of Philosophy, University of Amsterdam; and Shaw at the National Institute of Health and Care Excellence, UK. This research way supported by the UK Arts and Humanities Research Council and the Leverhulme Trust.
Bibliographic Information
Book Title: Evaluating Evidence of Mechanisms in Medicine
Book Subtitle: Principles and Procedures
Authors: Veli-Pekka Parkkinen, Christian Wallmann, Michael Wilde, Brendan Clarke, Phyllis Illari, Michael P Kelly, Charles Norell, Federica Russo, Beth Shaw, … Jon Williamson
Series Title: SpringerBriefs in Philosophy
DOI: https://doi.org/10.1007/978-3-319-94610-8
Publisher: Springer Cham
eBook Packages: Religion and Philosophy, Philosophy and Religion (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s) 2018
Softcover ISBN: 978-3-319-94609-2Published: 24 July 2018
eBook ISBN: 978-3-319-94610-8Published: 13 July 2018
Series ISSN: 2211-4548
Series E-ISSN: 2211-4556
Edition Number: 1
Number of Pages: XVIII, 125
Number of Illustrations: 14 b/w illustrations
Topics: Philosophy of Medicine, Epistemology