Transfusion Management of the Obstetrical Patient

1. Front Matter

   Pages i-xvi

   PDF

2. Obstetrical Management of Postpartum Hemorrhage

   • Michael Dombrowski, Michael Paidas

   Pages 1-14

3. Laboratory Testing and Predictors of Severe Postpartum Hemorrhage

   • Evelyn Lockhart

   Pages 15-21

4. Component Therapy in Obstetric Hemorrhage

   • Joseph Griggs

   Pages 23-37

5. Evidence for 1:1:1 Transfusion Support and Importance of a Hemorrhage Protocol

   • Mark Fung, Sarah Harm

   Pages 39-45

6. Evidence for/Against Administration of Antifibrinolytic Agents During an Obstetrical Hemorrhage

   • Kerry L. O’Brien

   Pages 47-54

7. Evidence for/Against Administration of Fibrinogen Concentrate and Coagulation Factor Concentrate During an Obstetrical Hemorrhage

   • Michael Dombrowski, Michael Paidas

   Pages 55-66

8. Recommendations on Blood Recovery in Obstetrics

   • Gerhardt Konig

   Pages 67-72

9. Thrombocytopenia in Pregnancy

   • Thomas G. DeLoughery

   Pages 73-80

10. Von Willebrand Disease in Pregnancy

    • Thomas G. DeLoughery

    Pages 81-90

11. Platelet Count and Neuraxial Anesthesia

    • Cathleen Peterson-Layne, Beth R. Burton

    Pages 91-96

12. ABO Compatibility

    • Theresa Nester

    Pages 97-101

13. RhD Compatibility

    • Jessica Poisson

    Pages 103-106

14. Other Rh Antibodies That Can Impact Transfusion

    • Jessica Poisson

    Pages 107-111

15. Importance of Getting a Sample for ABO Type Early in a Resuscitation

    • Ashok Nambiar

    Pages 113-120

16. Risks of Giving Uncrossmatched Red Cells

    • Ashok Nambiar

    Pages 121-129

17. Management of Thrombotic Microangiopathies in Pregnancy

    • Jeffrey L. Winters, Vesna D. Garovic, Layana Alrahmani, Kristina A. Davis

    Pages 131-153

18. Hyperhemolysis Syndrome in a Pregnant Woman with Sickle Cell Anemia

    • Henry Hilt, Oyebimpe Adesina

    Pages 155-161

19. Fetal and Neonatal Alloimmune Thrombocytopenia

    • Justin Juskewitch, Jeffrey L. Winters

    Pages 163-178

20. Weak D in Pregnancy

    • Meghan Delaney

    Pages 179-186

This clinical casebook covers transfusion medicine theory and its practical implications for the obstetrical hemorrhage patient through the presentation of cases on actively bleeding patients. Each case features a unique clinical scenario involving a bleeding patient and outlines different aspects of safe and effective transfusion support. The cases contain current evidence on the latest topics in the field, such as the use of antifibrinolytic agents and coagulation factor concentrates in the setting of massive obstetrical hemorrhage. In addition to the actively bleeding patient, the casebook includes other important management topics, including the role of plasma exchange in thrombotic microangiopathies during pregnancy; treatment of hyperhemolysis in a patient with hemoglobinopathy; and recommended management of patients with red cell antibodies found on prenatal testing. Other immunohematology topics such as post-natal management of an RhD negative woman for the prevention of hemolytic disease of the newborn due to anti-Rh(D) are included.


Written by transfusion medicine, coagulation, obstetrical, and anesthesiology experts, Transfusion Management of the Obstetrical Patient: A Clinical Casebook is a concise yet comprehensive resource for anesthesiologists, obstetricians, pathologists, hematologists, and other practitioners who treat obstetrical hemorrhage patients.

• Thrombocytopeni
• von Willebrand disease
• HELLP syndrome
• antifibrinolytics
• anti-Rh(D) formation
• anti-c

“The book is particularly well suited for a senior resident, fellow, or an attending starting out who is caring for patients in labor. Other obstetrical and/or anesthesia providers including medical students and junior residents will also benefit from the book … . casebook by Nester summarizes current evidence and can be used as a ‘starter kit’ for those who wish to integrate and enhance their specific transfusion-related knowledge into the management of obstetrical care using a multifaceted approach.” (Yao Zhang, Danran Zhou and Jie Zhou, Anesthesia & Analgesia, Vol. 129 (3), September 2019)

“This pocket-sized, softcover casebook is a jewel. Short, concise, clear, and current with contemporary practice … . For attention deficit-afflicted readers, the clinical pearls/pitfalls sections are pithy, rich in wisdom and experience, and well suited to memorization and quick implementation in daily practice. I would highly recommend it to providers in obstetrics training or practice and to those early in their laboratory medicine or clinical laboratory science training to gain a ‘holistic’ understanding of transfusion for obstetrical patients.” (Valerie L. Ng, Doody's Book Reviews, September, 2018)

• University of Washington Medical Center, Bloodworks Northwest, Seattle, USA

  Theresa Nester

Theresa Nester, MD
Medical Director of Integrated Transfusion Service Laboratories
Program Director, Transfusion Medicine Fellowship
Bloodworks Northwest
University of Washington Medical Center
Department of Laboratory Medicine
Seattle, WA 
USA

 

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