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  • © 2013

Genomics of Pattern Recognition Receptors

Applications in Oncology and Cardiovascular Diseases

  • Summarizes the field and indicates key directions

  • Explores and analyzes genomic variations

  • With numerous tables presenting the data systematically

  • Includes supplementary material: sn.pub/extras

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Table of contents (9 chapters)

  1. Front Matter

    Pages i-xi
  2. Structural Genomic Variation in TLR4 Gene and Cancer

    • Anton G. Kutikhin, Arseniy E. Yuzhalin
    Pages 33-55
  3. Structural Genomic Variation in Other Toll-Like Receptors and Cancer

    • Anton G. Kutikhin, Arseniy E. Yuzhalin
    Pages 57-76
  4. Structural Genomic Variation in Toll-Like Receptor Signaling Pathway and Cancer

    • Anton G. Kutikhin, Arseniy E. Yuzhalin
    Pages 77-100
  5. Structural Genomic Variation in Toll-like Receptor Pathway and Prostate Cancer

    • Anton G. Kutikhin, Arseniy E. Yuzhalin
    Pages 101-121
  6. Structural Genomic Variation in NOD-Like Receptors and Cancer

    • Anton G. Kutikhin, Arseniy E. Yuzhalin
    Pages 123-151
  7. Hot Spots in the Field: Where Should We Go?

    • Anton G. Kutikhin, Arseniy E. Yuzhalin
    Pages 169-176
  8. Back Matter

    Pages 177-185

About this book

This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.

Reviews

From the reviews:

“This book comprehensively covers the polymorphism of genes-encoding pattern recognition receptors (PRRs) … . The book is intended for immunologists, cancer researchers, cardiologists, epidemiologists, microbiologists, and geneticists, as well as PhD, graduate, and undergraduate students of biomedical faculties and their lecturers. This is a unique book that analyzes the field of PRR genomics and its practical applications. … This book will be quite useful for a very wide audience.” (Omer Iqbal, Doody’s Book Reviews, March, 2014)

Authors and Affiliations

  • Epidemiology, Kemerovo State Medical Academy, Kemerovo, Russia

    Anton G. Kutikhin

  • Res Inst Cardiovascular Diseases, Russian Academy of Medical Sciences Siberian Branch, Kemerovo, Russia

    Arseniy E. Yuzhalin

Bibliographic Information

  • Book Title: Genomics of Pattern Recognition Receptors

  • Book Subtitle: Applications in Oncology and Cardiovascular Diseases

  • Authors: Anton G. Kutikhin, Arseniy E. Yuzhalin

  • DOI: https://doi.org/10.1007/978-3-0348-0688-6

  • Publisher: Springer Basel

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Basel 2013

  • Hardcover ISBN: 978-3-0348-0687-9Published: 10 September 2013

  • Softcover ISBN: 978-3-0348-0794-4Published: 26 August 2015

  • eBook ISBN: 978-3-0348-0688-6Published: 28 August 2013

  • Edition Number: 1

  • Number of Pages: XI, 185

  • Topics: Receptors, Immunology, Cancer Research, Human Genetics, Oncology, Cardiology

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access