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Penile Carcinoma

Therapeutic Principles and Advances

  • Presents a comprehensive and state-of the-art approach to caring for penile carcinoma patients

  • Written by international experts in the field

  • Introduces novel systemic therapies and most recent advancements of diagnostic approach

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-xiii
  2. Mechanism of Carcinogenesis and Progression

    • Gigi Vos, Laura Elst, Maarten Albersen
    Pages 1-10
  3. Tumor Pathophysiology and Staging

    1. Front Matter

      Pages 11-11
    2. Pathologic Features of Invasive Penile Carcinomas and Precursor Lesions

      • Alcides Chaux, Sofia Canete-Portillo, George J. Netto
      Pages 13-27
    3. IIIB: Characterization of Penile Cancers with Comprehensive Genomic Profiling

      • Jeffrey S. Ross, Joseph Jacob, Gennady Bratslavsky
      Pages 29-45
    4. Functional and Psychosocial Impact of Penile Cancer Treatments

      • Grant R. Pollock, Jiping Zeng, Juan Chipollini
      Pages 47-55
  4. Management of Primary Penile Tumors

    1. Front Matter

      Pages 57-57
    2. Penile-Sparing Surgical and Non-Surgical Approaches

      • Marta Skrodzka, Benjamin Ayres, Nicholas Watkin
      Pages 59-73
    3. Management of Primary Penile Tumours: Partial and Total Penectomy

      • Karl H. Pang, Hussain M. Alnajjar, Asif Muneer
      Pages 75-84
  5. Management of Inguinal and Pelvic Lymph Nodes

    1. Front Matter

      Pages 85-85
    2. In the Clinical Setting of Non-Palpable/Non-Bulky Inguinal Nodes

      • Reza Nabavizadeh, Grace Lee, Katherine Bobrek, Viraj A. Master
      Pages 87-95
    3. Management of Bulky Inguinal/Pelvic Metastases in Squamous Penile Cancer

      • Mohamed E. Ahmed, Vidhu B. Joshi, Curtis A. Pettaway, R. Jeffrey Karnes, Philippe E. Spiess
      Pages 97-107
    4. Neoadjuvant and Adjuvant Multimodality Treatments for Patients with Lymph Node Involvement

      • Marco Bandini, Peter A. S. Johnstone, Andrea Necchi
      Pages 109-116
    5. Management of Metastatic Penile Cancer

      • Bradley A. McGregor, Guru P. Sonpavde
      Pages 125-132
  6. Novel Therapeutic Approaches

    1. Front Matter

      Pages 133-133
    2. Overview of Insightful Systemic Approaches

      • Savan Shah, Malek Saad, Jad Chahoud
      Pages 135-143
    3. Clinical Trials Corner

      • Andrea Necchi, Philippe E. Spiess
      Pages 145-150
  7. Back Matter

    Pages 151-154

About this book

This book provides a comprehensive and state-of the-art approach to caring for penile carcinoma patients and provides foundational information related to the molecular pathways implicated in penile carcinogenesis and progression. Penile carcinoma remains one of the most debilitating and life-altering malignancies to affect men, with significant impacts on quality of life, erectile function/sexual activity, and length of life. This book illuminates recent advances in penile cancer sparing treatment approaches and oncologically appropriate therapeutic options that help to maintain quality of life, sexual function, and intimacy for patients. It also elucidates recent understandings of human papilloma virus (HPV) and non-HPV driven pathways, which are suspected to have distinct treatment responses and prognoses. The book explores the management of inguinal lymph nodes in the setting of penile cancer, which can now be managed with the integration of key surgical principles/techniques including the adoption of minimally invasive surgery. Considering a multidisciplinary treatment approach for patients exhibiting either locally advanced or more widespread metastatic disease, the book introduces novel systemic therapies currently in development. Further, this book raises clinician awareness of the significant psychosocial impact of penile carcinoma on patients and their families.

Penile Carcinoma: Therapeutic Principles and Advances provides readers with the necessary knowledge and insight to care for penile cancer patients with the use of truly state-of-the-art diagnostic and therapeutic approaches. Cancer patients and their families will greatly benefit from adoption of these principles and the accessibility of such advances to their personalized care.



Editors and Affiliations

  • Department of Genito-Urinary Oncology, Department of Tumor Biology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, USA

    Philippe E. Spiess

  • Vita-Salute San Raffaele University, IRCCS San Raffaele Hospital and Scientific Institute, Milan, Italy

    Andrea Necchi

About the editors

Philippe E. Spiess

Senior Member, Department of GU Oncology
Senior Member, Department of Tumor Biology
Assistant Chief of Surgical Services
Moffitt Cancer Center
Professor, Department of Urology
University of South Florida
Tampa, Florida
USA


Andrea Necchi
Associate Professor, Vita-Salute San Raffaele University
Head of Genitourinary Medical Oncology
IRCCS San Raffaele Hospital and Scientific Institute
Via Olgettina 60, 20132
Milan, Italy



Bibliographic Information

  • Book Title: Penile Carcinoma

  • Book Subtitle: Therapeutic Principles and Advances

  • Editors: Philippe E. Spiess, Andrea Necchi

  • DOI: https://doi.org/10.1007/978-3-030-82060-2

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2021

  • Hardcover ISBN: 978-3-030-82059-6Published: 23 September 2021

  • Softcover ISBN: 978-3-030-82062-6Published: 24 September 2022

  • eBook ISBN: 978-3-030-82060-2Published: 22 September 2021

  • Edition Number: 1

  • Number of Pages: XIII, 154

  • Number of Illustrations: 1 b/w illustrations, 24 illustrations in colour

  • Topics: Internal Medicine, Urology

Buy it now

Buying options

eBook USD 59.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 79.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access