Overview
- Gathers recent research on developmental programming and age-related disease
- Expert contributors describe the developmental origins of adult health and disease
- Benefits gerontology scholars, researchers, and clinicians, as well as the general public
Part of the book series: Healthy Ageing and Longevity (HAL, volume 9)
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Table of contents (15 chapters)
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Front Matter
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Experimental Study of DOHaD
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Front Matter
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Epidemiological Evidence
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Front Matter
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Perspectives and Implications
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Front Matter
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Keywords
About this book
This book provides a comprehensive overview of the field of developmental programming of ageing phenotypes. Although gerontological research has traditionally focused on later stages of the life cycle, growing evidence indicates that both the rate of ageing-associated functional declines, and the risks of later-life chronic pathological conditions, can be traced to origins early in life.
While other books in the field concentrate on the developmental origin of particular disorders, this volume offers a detailed guide to all important aspects of the role of early-life conditions in programming both chronic pathological conditions and the ageing process.
Interest in the study of ageing and longevity had its beginnings in research on the fetal origins of adult disease. This has evolved into a hypothesis on the Developmental Origins of Adult Health and Disease (DOHaD), which postulates that adverse environmental exposures during critical in-utero and early postnatal stages of development may permanently change physiological responses and cause functional impairments and disorders in adult life.
In this book, the contributing authors and leading experts from around the world, describe research on mechanisms underlying the developmental programming phenomenon, as well as interventional strategies aimed at restoring developmentally disrupted epigenetic patterns.
Early Life Origins of Ageing and Longevity benefits a wide audience of working scientists, clinicians, and advanced students, and will also interest scientifically curious general readers who wish to know more about current research in this rapidly evolving field.
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Editors and Affiliations
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Bibliographic Information
Book Title: Early Life Origins of Ageing and Longevity
Editors: Alexander Vaiserman
Series Title: Healthy Ageing and Longevity
DOI: https://doi.org/10.1007/978-3-030-24958-8
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Switzerland AG 2019
Hardcover ISBN: 978-3-030-24957-1Published: 12 August 2019
Softcover ISBN: 978-3-030-24960-1Published: 13 August 2020
eBook ISBN: 978-3-030-24958-8Published: 29 July 2019
Series ISSN: 2199-9007
Series E-ISSN: 2199-9015
Edition Number: 1
Number of Pages: XI, 310
Number of Illustrations: 10 b/w illustrations, 17 illustrations in colour
Topics: Biogerontology, Developmental Biology, Gene Expression, Geriatrics/Gerontology