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Aggressive Lymphomas

  • Summarizes current knowledge of the biology and molecular pathogenesis
  • Reviews the state of the art in diagnostic and therapeutic strategies
  • Facilitates treatment choice in individual cases

Part of the book series: Hematologic Malignancies (HEMATOLOGIC)

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Table of contents (19 chapters)

  1. Front Matter

    Pages i-vii
  2. Epidemiology, Pathology and Molecular Pathogenesis

    1. Front Matter

      Pages 1-1
    2. Epidemiology of Aggressive Lymphomas

      • James R. Cerhan
      Pages 3-40
    3. Pathology and Molecular Pathogenesis of DLBCL and Related Entities

      • Laura Pasqualucci, German Ott
      Pages 41-73
    4. Pathology and Molecular Pathogenesis of Burkitt Lymphoma and Lymphoblastic Lymphoma

      • Hélène A. Poirel, Maria Raffaella Ambrosio, Pier Paolo Piccaluga, Lorenzo Leoncini
      Pages 75-94
    5. Pathology and Molecular Pathogenesis of T-Cell Lymphoma

      • Javeed Iqbal, Laurence de Leval
      Pages 95-141
  3. Standard of Care of Aggressive Lymphomas

    1. Front Matter

      Pages 143-143
    2. Standard of Care in First-Line Therapy of DLBCL

      • Greg Nowakowski, Fabian Frontzek, Norbert Schmitz
      Pages 145-155
    3. Standard of Care Relapsed DLBCL

      • Kayane Mheidly, Roch Houot, Michael Scordo, Craig Moskowitz
      Pages 157-166
    4. Burkitt Lymphoma

      • Kieron Dunleavy, Martine Chamuleau
      Pages 167-175
    5. Human Immunodeficiency Virus-Related Lymphomas

      • Josep-Maria Ribera, Richard F. Little
      Pages 177-188
    6. Primary CNS Lymphoma

      • Agnieszka Korfel
      Pages 189-199
    7. Extranodal Localization of Aggressive Lymphoma

      • Jeremy S. Abramson, Armando López-Guillermo
      Pages 201-212
    8. CD20-Negative Aggressive Lymphomas

      • Jorge J. Castillo
      Pages 213-226
    9. Standard of Care in T-Cell Lymphoma

      • Alessandro Broccoli, Dai Chihara, Michelle A. Fanale, Pier Luigi Zinzani
      Pages 227-244
    10. Aggressive Lymphoma in Children and Adolescents

      • Birte Wistinghausen, Birgit Burkhardt
      Pages 245-282
  4. Future Directions in Aggressive Lymphomas

    1. Front Matter

      Pages 283-283
    2. Role of Modern Imaging with FDG-PET/CT in Aggressive Lymphoma

      • Judith Trotman, Michel Meignan
      Pages 285-295
    3. Kinase Inhibitors in Large Cell Lymphoma

      • Franck Morschhauser, Salomon Manier, Nathan Fowler
      Pages 297-305
    4. Immunological Approaches

      • Guillaume Cartron, F. Frontzek, N. Schmitz
      Pages 307-324

About this book

This book summarizes current knowledge of the biology and molecular pathogenesis of aggressive lymphomas and reviews the state of the art in diagnostic and therapeutic strategies. The aim is both to provide the reader with a sound understanding of the very significant progress that has been achieved in the understanding and management of these malignancies over recent years and to facilitate appropriate choice of the therapeutic strategy in individual cases. The assessment of different prognostic parameters are clearly presented in order to permits effective risk stratification that impacts on treatment choice. Recent insights into lymphomagenesis are exemplified and may assist in identifying emerging therapeutic targets. The comprehensive and up-to-date nature of the book will make it an ideal reference for all physicians and researchers interested in lymphoma, including clinicians from various medical specialties, biologists, pathologists, radiologists and nuclear medicine specialist, as well as students.

Editors and Affiliations

  • Department of Translational Oncology, University-Hospital Münster, Münster, Germany

    Georg Lenz

  • Department of Hematology, University Claude Bernard Lyon 1, Pierre-Benite cedex, France

    Gilles Salles

About the editors

Professor Georg Lenz is Director of the Department of Medicine A, Hematology, Oncology and Pneumology at the University Hospital in Münster, Germany. Before his move to Münster he previously worked at the Ludwig-Maximilians University Munich, the National Cancer Institute in Bethesda (USA), and the Charité - Universitätsmedizin Berlin. His basic and clinical research focuses on the molecular characterization of malignant lymphomas and the performance of clinical trials using specific therapeutics.

Professor Gilles Salles is Head of the Hematology Department in Lyon University Hospitals (Hospices Civils de Lyon & Université Claude Bernard Lyon-1) and co-director of the research team “Clinical and Experimental Models of Lymphoma” at the Cancer Research Center of Lyon (Institut National de la Santé et de la Recherche Médicale).  He trained in Hematology and Immunology at the Université Claude Bernard in Lyon and at the Dana Farber Cancer Institue (Havard Medical Scholl, Boston, USA). He conducted several leading international clinical trials as well as translational studies in the field of lymphoma.

Bibliographic Information

  • Book Title: Aggressive Lymphomas

  • Editors: Georg Lenz, Gilles Salles

  • Series Title: Hematologic Malignancies

  • DOI: https://doi.org/10.1007/978-3-030-00362-3

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2019

  • Hardcover ISBN: 978-3-030-00361-6Published: 15 January 2019

  • eBook ISBN: 978-3-030-00362-3Published: 27 December 2018

  • Series ISSN: 2197-9766

  • Series E-ISSN: 2197-9774

  • Edition Number: 1

  • Number of Pages: VII, 360

  • Number of Illustrations: 5 b/w illustrations, 65 illustrations in colour

  • Topics: Hematology, Pathology, Immunology

Buy it now

Buying options

eBook USD 109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 139.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access