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Molecular Testing in Cancer

  • Book
  • © 2014

Overview

Editors:
  1. George M. Yousef

    1. Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada

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    You can also search for this editor in PubMed   Google Scholar

  2. Serge Jothy

    1. Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Written by experts in this field

  • Illustrated with high quality color microphotographs

  • Formatted for ease of use in the lab

  • Includes supplementary material: sn.pub/extras

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Table of contents (26 chapters)

  1. Front Matter

    Pages i-xi
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  2. Molecular Approaches and Techniques

    1. Front Matter

      Pages 1-1
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    2. Transitioning Diagnostic Molecular Pathology to the Genomic Era: Cancer Somatic Mutation Panel Testing

      • Kitchener D. Wilson, Iris Schrijver
      Pages 3-13

    3. Conventional and Molecular Cytogenetics in Cancer

      • Michelle Dolan
      Pages 15-25

    4. Comparative Genomic Hybridization and Array Based CGH in Cancer

      • Roland Hubaux, Victor D. Martinez, David Rowbotham, Wan L. Lam
      Pages 27-37

    5. Polymerase Chain Reaction

      • Maria Pasic, Carlo Hojilla, George M. Yousef
      Pages 39-54

    6. Single Nucleotide Polymorphisms (SNPs)

      • Jyotsna Batra, Srilakshmi Srinivasan, Judith Clements
      Pages 55-80

    7. Clinical Application of DNA Sequencing: Sanger and Next-Generation Platforms

      • John D. McPherson
      Pages 81-85

    8. Microarray-Based Investigations in Cancer

      • Maud H. W. Starmans, Syed Haider, Cindy Yao, Philippe Lambin, Paul C. Boutros
      Pages 87-106

    9. Proteomics in Cancer Diagnostics

      • Kevin P. Conlon, Delphine Rolland, Kojo S. J. Elenitoba-Johnson
      Pages 107-117

    10. Circulating Tumor Cells: A Noninvasive Liquid Biopsy in Cancer

      • Evi S. Lianidou
      Pages 119-132

  3. Molecular Applications in Various Malignancies

    1. Front Matter

      Pages 133-133
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    2. Molecular Testing in Hematologic Malignancies

      • Amir Behdad, Bryan L. Betz, Megan S. Lim, Nathanael G. Bailey
      Pages 135-167

    3. Molecular Testing in Breast Cancer

      • Dimitrios Zardavas, Debora Fumagalli, Christos Sotiriou
      Pages 169-188

    4. Molecular Pathology of Gastrointestinal Tumors

      • Andrea Grin, Serge Jothy
      Pages 189-209

    5. Molecular Testing in Pulmonary Tumors

      • Jeffrey J. Tanguay, Shirin Karimi, David M. Hwang, Ming-Sound Tsao
      Pages 211-228

    6. Molecular testing in Gynecological Malignancies

      • Pamela M. Ward, Louis Dubeau
      Pages 229-241

    7. Molecular Testing in CNS tumors

      • Jason Karamchandani
      Pages 243-255

    8. RETRACTED CHAPTER: Molecular Testing in Adult Kidney Tumors

      • Manal Y. Gabril, George M. Yousef
      Pages 257-275

    9. Molecular Testing in Prostate Cancer

      • Manal Y. Gabril, George M. Yousef
      Pages 277-300
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Keywords

About this book

Molecular Testing in Cancer provides a state of the art review of clinically relevant molecular pathology in cancer. The book provides a brief, easy to read review of commonly employed diagnostic molecular techniques including recently developed "next generation" analytic tools, and offers a system-based run-through of the utility of molecular testing in individual cancer types, as well as reviewing current markers in cancer diagnosis, prognosis, and management. The volume also provides a prospective for the future which includes recently characterized and emerging biomarkers.

Written by experts in the field, Molecular Testing in Cancer serves as a useful and comprehensive resource for pathologists, hematologists, laboratory technicians and molecular scientists.

Editors and Affiliations

  • Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada

    George M. Yousef, Serge Jothy

About the editors

George M. Yousef, MD, PhD
University of Toronto, Department of Laboratory Medicine and Pathobiology, Toronto, ON, Canada

Serge Jothy, MD, PhD
University of Toronto, Department of Laboratory Medicine and Pathobiology, Toronto, ON, Canada

Bibliographic Information

  • Book Title: Molecular Testing in Cancer

  • Editors: George M. Yousef, Serge Jothy

  • DOI: https://doi.org/10.1007/978-1-4899-8050-2

  • Publisher: Springer New York, NY

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media New York 2014

  • Hardcover ISBN: 978-1-4899-8049-6Published: 22 April 2014

  • Softcover ISBN: 978-1-4939-4555-9Published: 03 September 2016

  • eBook ISBN: 978-1-4899-8050-2Published: 21 April 2014

  • Edition Number: 1

  • Number of Pages: XI, 442

  • Number of Illustrations: 3 b/w illustrations, 84 illustrations in colour

  • Topics: Pathology, Hematology, Laboratory Medicine, Cancer Research

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