Spinal Afferent Processing

1. Front Matter

   Pages i-xxiii

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2. A Short Biography of F. W. L. Kerr, M.D.

   • Tony L. Yaksh

   Pages 1-18

3. Sensory Receptors of the Skin

   • Richard K. Winkelmann

   Pages 19-57

4. Primary Afferents and Hyperalgesia

   • James N. Campbell, Richard A. Meyer

   Pages 59-81

5. Nonclassical Features of Dorsal Root Ganglion Cell Organization

   • Richard E. Coggeshall

   Pages 83-96

6. Organization of Dorsal Horn Neurotransmitter Systems

   • Carole C. LaMotte

   Pages 97-116

7. Neurotransmitter Receptor Sites in the Spinal Cord

   • Virginia S. Seybold

   Pages 117-139

8. The Pattern and Place of Nociceptive Modulation in the Dorsal Horn

   • M. A. Ruda

   Pages 141-164

9. The Central Pharmacology of Primary Afferents with Emphasis on the Disposition and Role of Primary Afferent Substance P

   • Tony L. Yaksh

   Pages 165-195

10. Dorsal Horn Neurons and Their Sensory Inputs

    • Fernando Cervero

    Pages 197-216

11. Spinal Substrates of Visceral Pain

    • Robert D. Foreman

    Pages 217-242

12. Ascending Somatosensory Systems

    • William D. Willis Jr.

    Pages 243-274

13. The Spinal Pathways Contributing to the Ascending Conduction and the Descending Modulation of Pain Sensations and Reactions

    • Charles J. Vierck Jr., Joel D. Greenspan, Louis A. Ritz, David C. Yeomans

    Pages 275-329

14. Sensory-Discriminative Capacities of Nociceptive Pathways and Their Modulation by Behavior

    • Ronald Dubner, M. Catherine Bushnell, Gary H. Duncan

    Pages 331-344

15. Detection Thresholds of Cutaneous Sensations in Health and Disease in Man

    • Peter J. Dyck

    Pages 345-362

16. Control Systems for Nociceptive Afferent Processing

    • Donna L. Hammond

    Pages 363-390

17. Modulatory Effects of Descending Systems on Spinal Dorsal Horn Neurons

    • G. F. Gebhart

    Pages 391-416

18. The Controversial Nature of the Evidence for Neuroplasticity of Afferent Axons in the Spinal Cord

    • Paul E. Micevych, Barbara E. Rodin, Lawrence Kruger

    Pages 417-443

19. The Question of How the Dorsal Horn Encodes Sensory Information

    • Donald D. Price

    Pages 445-466

20. Aspects of Sensory Processing through Convergent Neurons

    • Daniel Le Bars, Anthony H. Dickenson, Jean Marie Besson, Luis Villanueva

    Pages 467-504

Some 29 scientists from the fields of neuroanatomy, neurochemistry, neu­ rophysiology, neuropharmacology, and behavior have contributed their ef­ forts to this testimonial on behalf of the contributions made by Dr. F. W. L. Kerr to science and to those with whom he interacted. The intention of the contributors to this volume was to deal with the manifold advances that pertain to the substrates in spinal cord relating to the processing of sensory infor­ mation, a subject that in one form or another provoked time and again Kerr's native enthusiasm for research. The organization of the book follows a natural course from the peripheral innervation of the somatic and visceral organs (Winkelmann, Chapter 2) to the effective stimuli that activate these fibers and give rise to sensation under normal and pathological conditions (Campbell and Meyer, Chapter 3; Dubner and colleagues, Chapter 13; Dyck, Chapter 14) to the course these afferent systems take to enter the spinal cord (Coggeshall, Chapter 4) and to the organization of the systems through which this afferent information reaches the brain (Willis, Chapter 11; Vierck and colleagues, Chapter 12).

• anatomy
• brain
• neuroanatomy
• neurochemistry
• neuropharmacology
• physiology
• spinal cord

• Departments of Neurosurgery and Pharmacology, Mayo Clinic, Rochester, USA

  Tony L. Yaksh

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