Current Topics in Coronary Research

1. Front Matter

   Pages N1-xv

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2. Metabolic Control of Coronary Blood Flow

   1. Front Matter

      Pages 1-1

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   2. Challenges to the Adenosine Hypothesis for the Regulation of Coronary Blood Flow

      • Robert M. Berne, Rafael Rubio

      Pages 3-10

   3. Observations on the Effect of Changes in Arterial Oxygenation on Adenosine Induced Coronary Vasodilation

      • Thomas W. Moir, Paul K. Jones

      Pages 11-26

   4. Adenosine Metabolism: Properties of Dog Heart Microsomal 5′-Nucleotidase

      • Ray A. Olsson, Mary Kay Gentry, R. Stanley Townsend

      Pages 27-39

   5. Myocardial: Blood Purine Nucleoside Concentration Ratios in Canine Myocardium

      • Jerry A. Snow, Ray A. Olsson, Mary K. Gentry

      Pages 41-54

   6. Role of O2 in Control of the Coronary Capillary Reserve

      • Carl R. Honig, Jeannine Bourdeau-Martini

      Pages 55-71

   7. Coronary and Systemic Hemodynamics in Chemically Sympathectomized Dogs

      • J. Holtz, W. von Restorff, E. Bassenge

      Pages 73-80

3. Transmural Myocardial Flow Gradients

   1. Front Matter

      Pages 93-93

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   2. Factors Determining the Distribution and Adequacy of Left Ventricular Myocardial Blood Flow

      • Gerald D. Buckberg, Albert A. Kattus Jr.

      Pages 95-113

   3. Regional Changes in Intramyocardial Pressure Following Myocardial Ischemia

      • David T. Kelly, Bertram Pitt

      Pages 115-119

4. Coronary Collateral Circulation

   1. Front Matter

      Pages 131-131

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   2. Some Developments in the Concept of Collateral Circulation to the Myocardium

      • Frederick R. Mautz

      Pages 133-140

   3. Viewpoint of a Human Pathologist on the Current Coronary Problem

      • Giorgio Baroldi

      Pages 141-149

   4. The Distribution of Coronary and of Coronary Collateral Flow in Normal Hearts and After Chronic Coronary Occlusion

      • W. Schaper, W. Flameng, B. Wüsten, J. Palmowski

      Pages 151-160

   5. Local Oxygen Tension and Blood Flow in the Normal and Chronic Ischemic Myocardium in the Anesthetized Dog

      • W. Diederen, Rudolph Kadatz

      Pages 161-171

   6. Hemodynamic Evidence of the Development of Coronary Collateral Circulation in Conscious Dogs

      • Eric C. Elliot

      Pages 173-190

   7. The Effect of Glyceryl Trinitrate on Coronary Collateral Flow — A Preliminary Report

      • Edward M. Khouri, Agustin R. Iza

      Pages 191-196

5. Clinical Problems in the Coronary Circulation

   1. Front Matter

      Pages 217-217

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   2. Relation of Coronary Events to Spasm of Coronary Arteries, Precariousness of Obstructive Lesions and Availability of Collateral Channels

      • A. A. Kattus

      Pages 219-233

How can you adequately honor a man of deeds with mere words? Dr. Donald Eaton Gregg is recognized throughout the scientific world for his distinguished contributions to our knowledge of the coronary circulation, his advances in experimental instrumentation and design, his scientific integrity and his lasting influence on other investigators. His research associates over the years are now liberally scattered over the entire world. Their accomplishments and activities reflect the quality of their training in his Department of Cardiorespiratory Diseases at the Walter Reed Army Institute of Research. The positions of prestige occupied by these men attest to Dr. Gregg's ability to select and inspire men of talent, yet in his usual modest way he insists that he was only fortunate to be in the right place at the right time. Thus, at the time of Dr. Gregg's retirement as Chief of the Department of Cardiorespiratory Diseases, a position he has held since 1950, his associates thought that a scientific symposium was the most appropriate way to honor a man of his stature. Accordingly, on March 29-30, 1973 a Symposium on Current Topics in Coronary Research was held at the Walter Reed Army Institute of Research. Its objectives were to define our present state of knowl­ edge and, more importantly, define the basic questions requiring further experimentation in four major areas of coronary research, i. e.

• Bypass
• Dilatation
• artery
• circulation
• diseases
• heart
• heart disease
• hemodynamics
• instrumentation
• quality
• research
• training

• Department of Pathology, University of California at San Diego, La Jolla, USA

  Colin M. Bloor

• Division of Medicine, Walter Reed Army Institute of Research, USA

  Ray A. Olsson

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