Skip to main content
SpringerLink
Log in
Book cover

Vaccines

Recent Trends and Progress

  • Book
  • © 1991

Overview

Editors:
  1. Gregory Gregoriadis

    1. School of Pharmacy, University of London, London, UK

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Anthony C. Allison

    1. Syntex Research, Palo Alto, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  3. George Poste

    1. SmithKline Beecham Pharmaceuticals, King of Prussia, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: NATO Science Series A: (NSSA, volume 215)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (15 chapters)

  1. Front Matter

    Pages i-viii
    Download chapter PDF

  2. Dendritic Cells in the Induction of Immunity

    • Stella C. Knight
    Pages 1-6

  3. Escape Mechanisms of Viruses from Immune Responses and Their Relevance to Vaccine Design

    • Jean-Louis Virelizier
    Pages 7-12

  4. Enhanced Immunogenicity of Recombinant and Synthetic Peptide Vaccines

    • M. J. Francis
    Pages 13-23

  5. Immunomodulation by Adjuvants

    • R. Bomford, M. Stapleton, S. Winsor
    Pages 25-32

  6. Use of Syntex Adjuvant Formulation to Enhance Immune Responses to Viral Antigens

    • N. E. Byars, G. M. Nakano, M. Welch, A. C. Allison
    Pages 33-42

  7. Influenza Vaccines and the Wyeth-Ayerst Experience with Syntex Adjuvant

    • Richard N. Hjorth, Geraldine M. Bonde, Elizabeth D. Piner, Kenneth M. Goldberg, Daniel M. Teller, Mark Hite et al.
    Pages 43-58

  8. Nonionic Block Polymer Surfactants as Adjuvants in Vaccines

    • Guy J. W. J. Zigterman, Andre F. M. Verheul, Harm Snippe
    Pages 59-75

  9. Effects of Added Cytokines on Immune Responses and Memory

    • A. W. Heath, J. H. L. Playfair
    Pages 77-84

  10. The Assessment and Use of Adjuvants

    • D. E. S. Stewart-Tull
    Pages 85-92

  11. Efficient Anti-Idiotypic Immunization with Homologous, Virus Neutralizing Monoclonal Antibodies Conjugated with KLH and Combined with Quil A

    • Tom A. M. Oosterlaken, Theo Harmsen, Cornelis A. Kraaijeveld, Harm Snippe
    Pages 93-98

  12. Protein Conformation Affects the Efficacy of Pertussis Vaccines

    • A. Bartoloni, M. G. Pizza, A. Covacci, D. Nucci, L. Nencioni, R. Rappuoli
    Pages 99-105

  13. Vaccination Against Epstein-Barr Virus

    • M. A. Epstein
    Pages 107-112

  14. Adenovirus Vectored Vaccines

    • K-H. Hsu, M. Lubeck, S. Mizutani, R. Natuk, M. Chengalvala, P. Chanda et al.
    Pages 113-119

  15. Vaccines Against Bacterial Infections of Children

    • P. Helena Makela, Helena Kayhty, Aino K. Takala, Heikki Peltola, Juhani Eskola
    Pages 121-135

  16. Current Progress and Future Trends in Birth Control Vaccines

    • Norbert Dreifurst, Avrion Mitchison
    Pages 137-143

  17. Back Matter

    Pages 145-154
    Download chapter PDF
Back to top

Keywords

About this book

The success of vaccination in controlling infectious diseases is well documented. However, low profitability, expense and liability have hindered research and development of vaccines. Recently, increasing realization (enhanced by the AIDS pandemic) of the need to overcome such difficulties has led to steps being taken by national authorities, non-profit and commercial organizations to resolve them. This has been facilitated by developments in recombinant DNA techniques, the advent of monoclonal anti­ bodies and progress in the understanding of the immunological structure of proteins which have laid the foundation of a new generation of vaccines. Such vaccines are defined at the molecular level, can elicit immune responses controlling infectious organisms and are therefore potentially free of the problems encountered in conventional ones. Unfortunately, subunit and synthetic peptide vaccines are often only weakly or non­ inmunogenic. However, developments in both antigen production and immuno­ potentiation of weak antigens have opened new avenues with exciting prospects for vaccine design.

Editors and Affiliations

  • School of Pharmacy, University of London, London, UK

    Gregory Gregoriadis

  • Syntex Research, Palo Alto, USA

    Anthony C. Allison

  • SmithKline Beecham Pharmaceuticals, King of Prussia, USA

    George Poste

Bibliographic Information

  • Book Title: Vaccines

  • Book Subtitle: Recent Trends and Progress

  • Editors: Gregory Gregoriadis, Anthony C. Allison, George Poste

  • Series Title: NATO Science Series A:

  • DOI: https://doi.org/10.1007/978-1-4615-3848-6

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Plenum Press, New York 1991

  • Hardcover ISBN: 978-0-306-44044-1Published: 31 October 1991

  • Softcover ISBN: 978-1-4613-6717-8Published: 21 October 2012

  • eBook ISBN: 978-1-4615-3848-6Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: VIII, 154

  • Topics: Immunology, Pharmacology/Toxicology, Animal Anatomy / Morphology / Histology, Plant Sciences

Publish with us

Policies and ethics

Back to top

Search

Navigation