Lacrimal Gland, Tear Film, and Dry Eye Syndromes

1. Front Matter

   Pages i-xxii

   PDF

2. Keynote Address

   1. Regulation of Tear Secretion

      • Darlene A. Dartt

      Pages 1-9

3. Lacrimal Gland: Anatomy and Innervation

   1. The Anatomy and Innervation of Lacrimal Glands

      • Benjamin Walcott, Roger H. Cameron, Peter R. Brink

      Pages 11-18

   2. Light and Electron Microscopic Morphology of Accessory Lacrimal Glands

      • Peter Seifert, Manfred Spitznas, Frank Koch, Andrea Cusumano

      Pages 19-23

   3. Immunohistochemistry and Protein Secretion in the Rat Lacrimal Gland: a Morphophysiological Study

      • Jaipaul Singh, Ernest Adeghate, Shuna Burrows, Frank C. Howarth, Ruth M. Williams

      Pages 25-30

   4. Carbonic Anhydrase and Acinar Cell Heterogeneity in Rat and Rabbit Lacrimal Glands

      • B. Britt Bromberg, Cynthia W. Hanemann, Mary H. Welch, Roger W. Beuerman, Sherwood Githens

      Pages 31-36

   5. Basement Membrane Modulation of Stimulated Secretion by Lacrimal Acinar Cells

      • Gordon W. Laurie, J. Douglas Glass, Rebecca A. Ogle

      Pages 37-44

   6. Galactose-Binding Sites in the Acinar Cells of the Human Accessory Lacrimal Gland

      • Winrich Breipohl, Manfred Spitznas, Fred Sinowatz, Oliver Leip, Wallid Naib-Majani, Andrea Cusumano

      Pages 45-48

   7. Thoughts on the Ductules of the Aging Human Lacrimal Gland

      • Orkan George Stasior, Janet L. Roen

      Pages 49-52

   8. The Parenchyma Accompanying Major Extraglandular Ducts within the Rat Lacrimal Cord

      • Mortimer Lorber

      Pages 53-56

   9. Protein Secretion and the Identification of Neurotransmitters in the Isolated Pig Lacrimal Gland

      • Jaipaul Singh, Ernest Adeghate, Shuna Burrows, Frank C. Howarth, Tibor Donath

      Pages 57-60

   10. Anti-Muscarinic Acetylcholine Receptor-Like Immunoreactivity in Lacrimal Glands

       • Benjamin Walcott, Roger Cameron, Elizabeth Grine, Elizabeth Roemer, Monica Pastor, Peter R. Brink

       Pages 61-65

   11. Innervation and Mast Cells of the Rat Lacrimal Gland: the Effects of Age

       • Ruth M. Williams, Jaipaul Singh, Keith A. Sharkey

       Pages 67-74

   12. Immunogold Localization of Prolactin in Acinar Cells of Lacrimal Gland

       • Richard L. Wood, Kyung-Ho Park, J. Peter Gierow, Austin K. Mircheff

       Pages 75-77

4. Lacrimal Gland: Electrophysiology, Water and Ion Transport

   1. Subcellular Organization of Ion Transporters in Lacrimal Acinar Cells: Secretagogue-Induced Dynamics

      • Austin K. Mircheff, Ross W. Lambert, Robert W. Lambert, Carol A. Maves, J. Peter Gierow, Richard L. Wood

      Pages 79-86

   2. Effect of Acetylcholine on the Membrane Conductance of the Intralobular Duct Cells of the Rat Exorbital Lacrimal Gland

      • Yoshitaka Saito, Soichiro Kuwahara

      Pages 87-92

   3. The Circadian Rhythm of Lacrimal Secretion and its Parameters, Determined in a Group of Healthy Individuals, and its Potential Diagnostic and Therapeutic Significance

      • Amalia Romano, Adrian Peisich, Bogidar Madjarov

      Pages 93-97

   4. Effects of Dihydrotestosterone and Prolactin on Lacrimal Gland Function

      • Dwight W. Warren, Ana Maria Azzarolo, Laren Becker, Kirsten Bjerrum, Renee L. Kaswan, Austin K. Mircheff

      Pages 99-104

   5. A Na:H Exchanger Subtype Mediates Volume Regulation in Bovine Corneal Epithelial Cells

      • Peter Reinach, Vadivel Ganapathy, Viviana Torres-Zamorano

      Pages 105-110

   6. Endocytosis and Exocytosis in Rabbit Lacrimal Gland Acinar Cells

      • J. Peter Gierow, Richard L. Wood, Austin K. Mircheff

      Pages 111-114

During the past decade a significant international research effort has been directed towards understanding the composition and regulation of the preocular tear film. This effort has been motivated by the recognition that the tear film plays an essential role in maintaining corneal and conjunctival integrity, protecting against microbial challenge and preserving visual acuity. In addition, research has been stimulated by the knowledge that alteration or deficiency of the tear film, which occurs in countless individuals throughout the world, may lead to desiccation of the ocular surface, ulceration and perforation of the cornea, an increased incidence of infectious disease, and potentially, pronounced visual disability and blindness. 7 To promote further progress in this field of vision research, the International Conference on the Lacrimal Gland, Tear Film and Dry Eye Syndromes: Basic Science and Clinical Relevance was held in the Southampton Princess Resort in Bermuda from November 14 to 17, 1992. This meeting was designed to assess critically the current knowledge and 'state of the art' research on the structure and function of lacrimal tissue and tears in both health and disease. The goal of this conference was to provide an international exchange of information that would be of value to basic scientists involved in eye research, to physicians in the ophthalmological community, and to pharmaceutical companies with an interest in the treatment of lacrimal gland, tear film or ocular surface disorders (e. g. Sjogren's syndrome).

• Antigen
• Drogen
• Flora
• HIV
• Pathogene
• Transplantation
• autoimmune disease
• infections
• physiology
• transcription
• viscoelastic properties

• Schepens Eye Research Institute and Harvard Medical School, Boston, USA

  David A. Sullivan

Policies and ethics