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  • Conference proceedings
  • © 2013

Proceedings of the Fourth Seattle Symposium in Biostatistics: Clinical Trials

  • Covers wide range of advances in clinical trials research
  • Many new techniques in the areas of biomarkers and the use of molecular and genetic bioinformatics are covered in detail
  • Includes articles by important biostatisticians working today
  • Includes supplementary material: sn.pub/extras

Part of the book series: Lecture Notes in Statistics (LNS, volume 1205)

Part of the book sub series: Lecture Notes in Statistics - Proceedings (LNSP)

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Table of contents (12 papers)

  1. Front Matter

    Pages i-viii
  2. Biomarkers: Role in the Design and Interpretation of Clinical Trials

    1. Front Matter

      Pages 1-1
  3. Biomarkers: Issues in Individualized Therapy

    1. Front Matter

      Pages 47-47
    2. Oncology Clinical Trials in the Genomic Era

      • Richard Simon, Jyothi Subramanian
      Pages 63-79
  4. Issues in Multi-Regional Clinical Trials

    1. Front Matter

      Pages 93-93
  5. Safety

    1. Front Matter

      Pages 117-117
    2. Quantitative Risk/Benefit Assessment: Where Are We?

      • Christy Chuang-Stein
      Pages 119-135
  6. Special Topics

    1. Front Matter

      Pages 175-175
    2. Genetic Markers in Clinical Trials

      • B. S. Weir, P. J. Heagerty
      Pages 209-245
  7. Back Matter

    Pages 247-249

About this book

This volume contains a selection of chapters base on papers presented at the Fourth Seattle Symposium in Biostatistics: Clinical Trials. The symposium was held in 2010 to celebrate the 40th anniversary of the University of Washington School of Public Health and Community Medicine. It featured keynote lectures by David DeMets and Susan Ellenberg and 16 invited presentations by other prominent researchers. The papers contained in this volume encompass recent methodological advances in several important clinical trials research, such as biomarkers, meta-analyses, sequential and adaptive clinical trials, and various genetic bioinformatic techniques. This volume will be a valuable reference for researchers and practitioners in the field of clinical trials.

Editors and Affiliations

  • University of Washington, Seattle, USA

    Thomas R. Fleming, Bruce S. Weir

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access