Overview
- Compiled information on cell adhesion molecules in human cancer tissue specimens
- Explains how cell adhesion influences DNA damage responses
- Explains how cell adhesion influences chemotherapeutic drug resistance
Part of the book series: Cancer Metastasis - Biology and Treatment (CMBT, volume 9)
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Table of contents (10 chapters)
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Front Matter
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Back Matter
Keywords
About this book
In this volume, the expression of specific adhesion molecules within human cancer tissues are highlighted. The expression signatures from published DNA microarray and immunohistochemistry studies are detailed. The concept that the alteration of specific adhesion molecules influence the cancer migration ability and cancer damage responses is detailed in this volume; both features are essential for the survival of an invading tumor cell. Defining the minimal adhesion receptors preserved on cancer cells during tumor progression will define the metastatic adhesion signature. Understanding the metastatic adhesion signature will reveal vulnerabilities that could be exploited for the prevention and/or eradication of the invading cancer cell.
Editors and Affiliations
Bibliographic Information
Book Title: Cell Adhesion and Cytoskeletal Molecules in Metastasis
Editors: Anne E. Cress, Raymond B. Nagle
Series Title: Cancer Metastasis - Biology and Treatment
DOI: https://doi.org/10.1007/978-1-4020-5129-6
Publisher: Springer Dordrecht
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Science+Business Media B.V. 2006
Hardcover ISBN: 978-1-4020-5128-9Published: 25 October 2006
Softcover ISBN: 978-90-481-7290-0Published: 30 November 2010
eBook ISBN: 978-1-4020-5129-6Published: 20 January 2007
Series ISSN: 1568-2102
Series E-ISSN: 2215-1648
Edition Number: 1
Number of Pages: XII, 196
Topics: Surgery, Cancer Research, Molecular Medicine, Dermatology, Oncology, Pathology