Skip to main content
  • Book
  • © 2021

Translational Methods for Multiple Sclerosis Research

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Neuromethods (NM, volume 166)

Buy it now

Buying options

eBook USD 109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (21 protocols)

  1. Front Matter

    Pages i-xi
  2. Pathophysiological Fingerprints of MS and Related Neuroimmunological Disorders

    1. Front Matter

      Pages 1-1
    2. White Matter Pathology

      • Angela Radetz, Sergiu Groppa
      Pages 29-46
    3. Pathophysiology of Grey Matter Affection in MS

      • Gabriel Gonzalez-Escamilla, Dumitru Ciolac
      Pages 47-60
    4. Translational Characterization of the Glia Role in Multiple Sclerosis

      • Dumitru Ciolac, Stanislav A. Groppa, Gabriel Gonzalez-Escamilla
      Pages 61-76
  3. Animal Models of Neuroinflammation

    1. Front Matter

      Pages 87-87
    2. Spontaneous Mouse Models of Neuroinflammation

      • Shin-Young Na, Gurumoorthy Krishnamoorthy
      Pages 89-107
    3. Chronic Progressive Models

      • Maren Lindner, Ann-Katrin Fleck, Luisa Klotz
      Pages 109-120
    4. Electrophysiological Measurements for Brain Network Characterization in Rodents

      • Manuela Cerina, Luca Fazio, Sven G. Meuth
      Pages 121-135
  4. Translation of Functional Domain Abnormalities from Human to Mice

    1. Front Matter

      Pages 137-137
    2. Translation of Functional Domain Abnormalities from Human to Mouse Motor System

      • Muthuraman Muthuraman, Dumitru Ciolac, Venkata Chaitanya Chirumamilla
      Pages 139-152
    3. Characterization of the Somatosensory System

      • Carsten H. Wolters, Marios Antonakakis, Asad Khan, Maria Carla Piastra, Johannes Vorwerk
      Pages 153-169
    4. Translational Research in Neuroimmunology: Cognition

      • Maren Person, Miriam Becke
      Pages 171-182
  5. Exploring Translational Paths in MS with Brain Imaging: Small Animal to Human Imaging Tools

    1. Front Matter

      Pages 197-197
    2. Human Structural MRI

      • Menno M. Schoonheim
      Pages 199-211
    3. Human Functional MRI

      • Paolo Preziosa, Paola Valsasina, Massimo Filippi, Maria A. Rocca
      Pages 213-236

About this book

This volume explores the recent advances in the study of translational paths in central inflammation and focuses on ongoing pathophysiological processes and the transition between inflammatory stages and progressive states with neurodegeneration. Chapters cover topics such as pathophysiological hallmarks of neuroinflammation from tissue damage to reorganization; connecting studies of mouse models; and investigations of humans with multiple sclerosis. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. 

Cutting-edge and practical, Translational Methods for Multiple Sclerosis Research is a valuable resource for researchers who want to learn more about this chronic ad progressive disease, and pave the way for new advancements. 



Editors and Affiliations

  • Department of Neurology and Neuroimaging Center (NIC) of the Focus Program Translational Neuroscience (FTN), University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany

    Sergiu Groppa

  • Department of Neurology, University of Düsseldorf, Düsseldorf, Germany

    Sven G. Meuth

Bibliographic Information

  • Book Title: Translational Methods for Multiple Sclerosis Research

  • Editors: Sergiu Groppa, Sven G. Meuth

  • Series Title: Neuromethods

  • DOI: https://doi.org/10.1007/978-1-0716-1213-2

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2021

  • Hardcover ISBN: 978-1-0716-1212-5Published: 24 May 2021

  • Softcover ISBN: 978-1-0716-1215-6Published: 23 May 2021

  • eBook ISBN: 978-1-0716-1213-2Published: 23 May 2021

  • Series ISSN: 0893-2336

  • Series E-ISSN: 1940-6045

  • Edition Number: 1

  • Number of Pages: XI, 333

  • Number of Illustrations: 2 b/w illustrations, 27 illustrations in colour

  • Topics: Neurosciences

Buy it now

Buying options

eBook USD 109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access