Editors:
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 2195)
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Table of contents (18 protocols)
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Front Matter
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Back Matter
About this book
This volume presents the latest techniques used to study germ cell tumors (GCTs), including histopathology; in vitro and in vivo techniques for investigating GCT biology; novel methods for detecting minimal residual diseases; and sequencing considerations as they apply to GCTs. Chapters cover topics such as clinical applications of immunohistochemistry in GCTs in men; fluorescence in situ hybridization (FISH) detection of chromosomal 12p anomalies in testicular GCTs; evaluation of chemotherapeutic drugs for treatment of (cisplatin-resistant) germ cell cancer cell lines; targeted methylation analyses; and circulating microRNA panel for malignant GCT diagnosis and monitoring. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and comprehensive, Testicular Germ Cell Tumors: Methods and Protocols provides valuable information that is useful for both novice and expert GCT researchers interested in learning more about this field.
Editors and Affiliations
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Department of Urology, UT Southwestern Medical Center, Dallas, USA
Aditya Bagrodia
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Cancer and Blood Disease Institute, Children’s Hospital Los Angeles, Departments of Pediatrics and Medicine, Keck School of Medicine, University of Southern California, Los Angeles, USA
James F. Amatruda
Bibliographic Information
Book Title: Testicular Germ Cell Tumors
Book Subtitle: Methods and Protocols
Editors: Aditya Bagrodia, James F. Amatruda
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-0716-0860-9
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2021
Hardcover ISBN: 978-1-0716-0859-3Published: 28 August 2020
Softcover ISBN: 978-1-0716-0862-3Published: 28 August 2021
eBook ISBN: 978-1-0716-0860-9Published: 27 August 2020
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XII, 278
Number of Illustrations: 5 b/w illustrations, 44 illustrations in colour
Topics: Developmental Biology, Cancer Research, Cell Biology