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Pediatric Inflammatory Bowel Disease

  • Book
  • © 2008

Overview

Editors:
  1. Petar Mamula

    1. Attending Physician, Division of GI Hepatology and Nutrition, Director Endoscopy Suite, The Children’s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, USA

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  2. Jonathan E. Markowitz

    1. Attending Physician, Children’s Center for Digestive Health, Greenville Hospital System University Medical Center, University of South Carolina School of Medicine, Greenville, USA

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  3. Robert N. Baldassano

    1. Attending Physician and Director, Inflammatory Bowel Disease Center Division of GI, Hepatology and Nutrition. The Children’s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, USA

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  • Emphasizes the pediatric aspects of Inflammatory Bowel Disease
  • Emphasis will be placed on visual aides within the textbook in the form of tables, figures, schemes, algorithms, as well as endoscopy and surgery images

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Table of contents (50 chapters)

  1. Front Matter

    Pages I-XXXIII
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  2. Etiology and Pathogenesis

    1. Front Matter

      Pages 1-1
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    2. Genetics of Inflammatory Bowel Diseases

      • Nancy McGreal, Judy H. Cho
      Pages 3-14

    3. Gut Immunity and Inflammatory Bowel Disease

      • William A. Faubion, Claudio Fiocchi
      Pages 15-29

    4. Cytokines and Inflammatory Bowel Disease

      • Edwin F. de Zoeten, Ivan J. Fuss
      Pages 31-41

  3. Epidemiology and Clinical Features

    1. Front Matter

      Pages 43-43
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    2. Epidemiology of Pediatric Inflammatory Bowel Disease

      • Shehzad Saeed, Subra Kugathasan
      Pages 45-60

    3. Early Onset Inflammatory Bowel Disease- Epidemiology and Clinical Features

      • Melvin B. Heyman, Neera Gupta
      Pages 61-65

    4. The Natural History of Pediatric Crohn Disease

      • James Markowitz
      Pages 67-74

    5. Natural History of Pediatric Ulcerative Colitis

      • Jeffrey S. Hyams
      Pages 75-81

    6. Natural History of Pediatric Indeterminate Colitis

      • Michael D. Kappelman, Richard J. Grand
      Pages 83-90

    7. Extraintestinal Manifestations of Pediatric Inflammatory Bowel Disease

      • Shervin Rabizadeh, Maria Oliva-Hemker
      Pages 91-101

    8. Growth Impairment in Pediatric Inflammatory Bowel Disease

      • Thomas D. Walters, Anne M. Griffiths
      Pages 103-117

    9. Skeletal Health in Pediatric Inflammatory Bowel Disease

      • Francisco Sylvester
      Pages 119-132

    10. Puberty and Pediatric-Onset Inflammatory Bowel Disease

      • Barbara S. Kirschner, Barry H. Rich
      Pages 133-142

    11. Classification of Pediatric Inflammatory Bowel Disease

      • Athos Bousvaros
      Pages 143-155

  4. Diagnosis

    1. Front Matter

      Pages 157-157
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    2. The History and Physical Exam in Pediatric Inflammatory Bowel Disease

      • Cheryl Blank, David J. Keljo
      Pages 159-163

    3. Differential Diagnosis of Pediatric Inflammatory Bowel Disease

      • Thierry Lamireau
      Pages 165-178

    4. Laboratory Evaluation of Pediatric Inflammatory Bowel Disease

      • Jennifer Strople, Benjamin D. Gold
      Pages 179-191
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Keywords

About this book

Pediatric Inflammatory Bowel Diseases (IBD) are the most common and most significant chronic disorders in Pediatric Gastroenterology. The onset of Crohn disease and ulcerative colitis in the first two decades of life presents a number of diagnostic and therapeutic challenges that are unique to pediatric patients. Although the studies available for pediatric diagnosis have improved dramatically in the past three decades, the improvement in technology alone cannot account for the increased frequency of IBD recognized in early childhood. While therapy for older patients has improved dramatically with the use of immunomodulators and the development of exciting biologic strategies, rarely if ever have comprehensive studies of the pharmacokinetics, safety and efficacy of any of the IBD medications been performed in pediatric patients. A number of excellent medications are not available in liquid preparations that can be swallowed by children, and others, such as timed-release formulations, are developed for delivery to an adult gastrointestinal tract. It is unfortunate that the care we provide to children is often an extrapolation of what is known about and available for adults with IBD. Pediatric patients with IBD face a number of unique challenges. The onset of disease before puberty can be devastating. Growth failure is a particularly difficult problem with potentially permanent consequences. Much of the pediatric specific research has focused on the role of nutritional therapy to treat growth failure and induce remission.

Reviews

From the reviews:

"This is a thorough discussion of pediatric inflammatory bowel disease … . written for pediatric gastroenterologists, the book is a useful reference for any person caring for pediatric inflammatory bowel disease patients, including residents, general pediatricians, adult gastroenterologists, and internists. … an outstanding review of pediatric IBD for anyone involved in the care of patients with this disorder. Topics … are discussed well in an easy-to-read manner with numerous references. The book is printed on high-quality, glossy paper allowing excellent reproduction of photographs … ." (Essam Imseis, Doody’s Review Service, August, 2008)

"This book provides a thorough update of the pathophysiology and clinical features of gastrointestinal disease in children … . Pediatric Inflammatory Bowel Disease will be an important resource primarily for pediatric gastroenterologists. However, all physicians who care for children with inflammatory bowel disease will find that it serves as a model for organizing clinicians to collectively advance the knowledge of the disorder through common clinical practice and participation in future research protocols." (Kathleen J. Motil, The New England Journal of Medicine, September, 2008)

Editors and Affiliations

  • Attending Physician, Division of GI Hepatology and Nutrition, Director Endoscopy Suite, The Children’s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, USA

    Petar Mamula

  • Attending Physician, Children’s Center for Digestive Health, Greenville Hospital System University Medical Center, University of South Carolina School of Medicine, Greenville, USA

    Jonathan E. Markowitz

  • Attending Physician and Director, Inflammatory Bowel Disease Center Division of GI, Hepatology and Nutrition. The Children’s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, USA

    Robert N. Baldassano

Bibliographic Information

  • Book Title: Pediatric Inflammatory Bowel Disease

  • Editors: Petar Mamula, Jonathan E. Markowitz, Robert N. Baldassano

  • DOI: https://doi.org/10.1007/978-0-387-73481-1

  • Publisher: Springer New York, NY

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag US 2008

  • eBook ISBN: 978-0-387-73481-1Published: 24 November 2007

  • Edition Number: 1

  • Number of Pages: XXXIV, 686

  • Number of Illustrations: 53 b/w illustrations, 60 illustrations in colour

  • Topics: Gastroenterology, Pediatrics, Internal Medicine

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