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Rb and Tumorigenesis

  • Book
  • © 2006

Overview

Authors:
  1. Maurizio Fanciulli

    1. Laboratory “B”, Regina Elena Cancer Institute, Rome, Italy

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  • Rb and Tumorigenesis describes the emerging roles of this important tumor suppressor, and its involvement in the control of development, apoptosis and cancer
  • Includes supplementary material: sn.pub/extras

Part of the book series: Medical Intelligence Unit (MIUN)

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Table of contents (9 chapters)

  1. Front Matter

    Pages i-ix
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  2. RB as a Positive Transcriptional Regulator during Epithelial Differentiation

    • Chantal E. Crémisi, Linda L. Pritchard
    Pages 1-10

  3. pRb in the Differentiation of Normal and Neoplastic Cells

    • Deborah Pajalunga, Grazia Camarda, Marco Crescenzi
    Pages 11-19

  4. Regulation of DNA Replication by the Retinoblastoma Tumor Suppressor Protein

    • Erik S. Knudsen, Steven P. Angus
    Pages 20-36

  5. New Insights into Transcriptional Regulation by Rb

    • Peggy J. Farnham
    Pages 37-45

  6. Regulation of Rb Function by Noncyclin Dependent Kinases

    • Jaya Padmanabhan, Srikumar P. Chellappan
    Pages 46-58

  7. Diverse Regulatory Functions of the E2F Family of Transcription Factors

    • Fred Dick, Nicholas Dyson
    Pages 59-72

  8. Regulation of E2F-Responsive Genes through Histone Modifications

    • Estelle Nicolas, Laetitia Daury, Didier Trouche
    Pages 73-80

  9. Emerging Roles for the Retinoblastoma Gene Family

    • Jacqueline L. Vanderluit, Kerry L. Ferguson, Ruth S. Slack
    Pages 81-105

  10. Rb and Cellular Differentiation

    • Lucia Latella, Pier Lorenzo Puri
    Pages 106-117

  11. Back Matter

    Pages 119-121
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Keywords

About this book

Rb and Tumorigenesis examines how recent advances have demonstrated the interaction of Rb with chromatin remodeling enzymes. This new title explores the potential roles of these interactions in Rb functions and provides some evidence that distinct Rb co-repressor may target different genes in different phases of the cell cycle.

Authors and Affiliations

  • Laboratory “B”, Regina Elena Cancer Institute, Rome, Italy

    Maurizio Fanciulli

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