AIDS in Africa

1. Front Matter

   Pages i-xx

   PDF

2. Introduction: The Etiology of AIDS

   • Max Essex, Souleymane Mboup

   Pages 1-10

3. The Molecular Virology of HIV-1

   • Monty Montano, Carolyn Williamson

   Pages 11-34

4. Immunopathogenesis of AIDS

   • Lynn S. Zijenah, David A. Katzenstein

   Pages 34-52

5. Effect of Genetic Variation on HIV Transmission and Progression to AIDS

   • Cheryl A. Winkler, Stephen J. O’Brien

   Pages 52-73

6. Biology of Human Immunodeficiency Virus Type 2 (HIV-2)

   • Phyllis J. Kanki, Jean-Louis Sankalé, Souleymane Mboup

   Pages 74-103

7. Simian Immunodeficiency Viruses and the Origin of HIVs

   • Ousmane M. Diop, Aïssatou Guèye, Ahidjo Ayouba, Eric Nerrienet, Sylvie Corbet, Philippe Mauclère et al.

   Pages 104-120

8. Serodiagnosis of HIV Infection

   • Aissatou Guèye-Ndiaye

   Pages 121-138

9. Molecular Diagnosis of HIV Infection

   • Boris Renjifo

   Pages 138-157

10. Monitoring HIV-1 Subtype Distribution

    • Francis R. Barin, Coumba Toure-Kane, Jean-Christophe Plantier, Martine Peeters

    Pages 158-173

11. Monitoring Viral Load

    • Phyllis J. Kanki, Indu Mani

    Pages 173-185

12. Monitoring Immune Function

    • Gunnel Biberfeld, Eligius Lyamuya

    Pages 185-199

13. The Epidemiology of HIV and AIDS

    • Peter Piot, Michael Bartos

    Pages 200-217

14. Transmission of HIV

    • Sibylle Kristensen, Moses Sinkala, Sten H. Vermund

    Pages 217-230

15. Role of Sexually Transmitted Diseases in HIV-1 Transmission

    • Saidi H. Kapiga, Iain W. Aitken

    Pages 231-250

16. Mother-to-Child Transmission of HIV

    • Anne Willoughby

    Pages 251-263

17. HIV-1 Subtypes and Recombinants

    • Boris Renjifo, Max Essex

    Pages 263-281

18. Current Estimates and Projections for the Epidemic

    • Karen A. Stanecki, Neff Walker

    Pages 281-296

19. Clinical Diagnosis of AIDS and HIV-Related Diseases

    • Churchill Lukwiya Onen

    Pages 297-321

20. Antiretroviral Therapy in Resource-Limited Settings

    • Anthony Amoroso, Charles E. Davis, Robert R. Redfield

    Pages 322-344

The way we deal with AIDS in Africa will All of them take account of the local cultural determine Africa’s future. The devastation context. But they all have something else in wrought by HIV/AIDS on the continent is so common; they stem from a political will to acute that it has become one of the main fight AIDS, and a recognition that facing up obstacles to development itself. AIDS to the problem is the first step towards c- threatens to unravel whole societies, com- quering it. I am convinced that, given that munities, and economies. In this way, AIDS will, every society can do the same. is not only taking away Africa’s present—it We have seen a growing understanding is taking away Africa’s future. of the inextricable link between prevention This crisis requires an unprecedented and treatment, and a conviction that tre- response. It requires communities, nations, ment can work even in the poorest societies. and regions, the public and the private sector, We have seen AIDS drugs become more international organizations and nongovern- available and affordable in poor countries, mental groups to come together in concerted, and scientific progress promises simplified coordinated action. Only when all these treatment regimes. Above all, we have seen a forces join in a common effort will we be able growing understanding that the key is poli- to expand our fight against the epidemic to cal commitment to providing treatment, decrease risk, vulnerability, and impact. All backed up by community involvement.

• AIDS
• Epidemiology
• HIV
• HIV infection
• HIV/AIDS
• cancer
• prevention

From the reviews:
"This updated and authoritative review of Africa's experience will be helpful to health care providers, researchers, and policy planners, not only in Africa but throughout the world, since Africa has had higher rates of infection and more experience with AIDS than other regions. Summing Up: Recommended. Appropriate for all levels."
(J.M. Howe, AIDS Information Center, VA Headquarters (DC) in Choice, 40:7 (March 2003)
"Written by leading experts in the field, this comprehensive reference book will be of interest to a wide audience of health care providers, researchers, and policy-makers. The authors have succeeded admirably in making technical material highly accessible."
(Jan Bongaarts in Population and Development Review, 29:3 (September 2003)

• Harvard AIDS Institute Mary Woodard Lasker Professor of Health Sciences Harvard University, Boston, USA

  Max Essex, Richard G. Marlink

• Laboratory of Bacteriology and Virology CHU Le Dantec, Université Cheikh Anta Diop, Dakar, Senegal

  Souleymane Mboup

• Department of Immunology and Infectious Diseases and the Harvard AIDS Institute, Harvard School of Public Health, Boston, USA

  Phyllis J. Kanki, Molly Holme

• Department of Nursing Education University of Botswana, Gaborone, Botswana

  Sheila D. Tlou

Policies and ethics