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Indicators of comorbidity in chronic broncho-obstructive pathology

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Abstract

We studied the issue of comorbidity in hospitalized patients with chronic obstructive pulmonary disease (COPD) and bronchial asthma (BA, control group). A correlation and regression analysis has shown a close direct relationship between the comorbidity index and age in patients with chronic broncho-obstructive pathology. By the summary comorbidity index, patients with chronic obstructive pulmonary disease differ significantly more than two times from those of the comparison group. An increase of the comorbidity index with an increase in the severity of chronic obstructive pulmonary disease and the worsening of the forecast mortality within 3 years in COPD compared with bronchial asthma have been revealed.

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References

  1. Anisimov, V.N., Molekulyarnye i fiziologicheskie mekhanizmy stareniya (Molecular and Physiological Mechanisms of Aging), St. Petersburg: Nauka, 2008, vol. 2.

    Google Scholar 

  2. Baturin, V.A. and Malykhin, F.T., Possible side effects of drugs in elderly patients with chronic obstructive pulmonary disease and associated pathology, Ter. Arkh., 2016, vol. 88, no. 3, pp. 100–107. doi 10.17116/terarkh2016883100-107

    Article  PubMed  Google Scholar 

  3. Baturin, V.A., Malykhin, F.T., and Shchetinin, E.V., The composition of microorganisms isolated from sputum in patients with lower respiratory tract infections and their sensitivity to antibacterial agents, depending on the age of the patients, the diagnosis, and previous treatment, Prof. Klin. Med., 2012, no. 2, pp. 48–51.

    Google Scholar 

  4. Bikbov, B.T. and Tomilina, N.A., The replacement therapy of patients with a chronic renal failure in the Russian Federation in 1998–2003, Nefrol. Dializ, 2005, no. 7, pp. 204–275.

    Google Scholar 

  5. Vertkin, A.L., Rumyantsev, M.A., and Skotnikov, A.S., Comorbidity in clinical practice. Part 1, Arkh. Vnutr. Med., 2011, no. 1, pp. 16–20.

    Google Scholar 

  6. Global Initiative for Chronic Obstructive Lung Disease (Updated 2014), Geneva: World Health Organization, 2015.

  7. Global Initiative for Chronic Obstructive Lung Disease (Updated 2014), Geneva: World Health Organization, 2015.

  8. Karoli, N.A. and Rebrov, A.P., Comorbidity in chronic obstructive pulmonary disease: a place of cardiovascular pathology, Rats. Farmakoter. Kardiol., 2009, no. 4, pp. 9–16.

    Article  Google Scholar 

  9. Kolosov, V.P., Trofimova, A.Yu., and Naryshkina, S.V., Kachestvo zhizni bol’nykh khronicheskoi obastruktivnoi bolezn’yu legkikh (Life Quality of Patients with Chronic Obstructive Pulmonary Disease), Blagoveshchensk: Dal’nevost. Nauch. Tsentr Fiziol. Patol. Dykhaniya, 2011.

    Google Scholar 

  10. Malykhin, F.T., Parameters of β-adrenoreception in elderly patients with exacerbation of chronic obstructive bronchitis, Vestn. Ross. Univ. Druzhby Narodov, Ser. Med., 2012, no. 1, pp. 43–45.

    Google Scholar 

  11. Malykhin, F.T., Improvement of the clinical-diagnostic process of chronic obstructive pulmonary disease in elderly patients, Sovrem. Probl. Nauki Obraz., 2013, no. 2, p. 110. http://www.science-education.ru/108-9095. Accessed September 5, 2016.

    Google Scholar 

  12. Malykhin, F.T. and Baturin, V.A., Analysis of the compliance of elderly patients with chronic obstructive pulmonary disease, Kazan. Med. Zh., 2014, vol. 95, no. 5, pp. 626–631.

    Google Scholar 

  13. Malykhin, F.T., Barabash, I.V., and Gusev, S.V., Parameters of external respiration in elderly and senile patients with chronic obstructive bronchitis, Klin. Gerontol., 2015, vol. 21, nos. 1–2, pp. 13–16.

    Google Scholar 

  14. Malykhin, F.T., Vizel’, A.A., and Vizel’, I.Yu., The use of mucoactive drugs in the therapist practice, Arkh. Vnutr. Med., 2013, no. 5 (13), pp. 10–15.

    Google Scholar 

  15. Malykhin, F.T. and Duman, T.S., A study of the life quality of patients with chronic obstructive pulmonary disease as part of its clinical diagnostics, Zdravookhr. Dal’nego Vostoka, 2011, vol. 4, no. 5, pp. 45–46.

    Google Scholar 

  16. Malykhin, F.T. and Kostornaya, I.V., Modern concepts on the morphological changes in the respiratory system in chronic obstructive pulmonary disease, Arkh. Patol., 2016, vol. 78, no. 1, pp. 42–50. doi 10.17116/ patol201678142-50

    Article  Google Scholar 

  17. Malykhin, F.T. and Khripunova, A.A., Research of gender and age aspects of medical and demographic losses of the population of Stavropol region due to chronic obstructive pulmonary disease, Sprav. Vracha Obshch. Prakt., 2014, no. 3, pp. 33–37.

    Google Scholar 

  18. Min’ko, A.A., Statisticheskii analiz v MS Excel (Statistical Analysis in MS Excel), Moscow: Vil’yams, 2004, pp. 382–399.

    Google Scholar 

  19. Skotnikov, A.S., Dokhova, O.M., and Shul’gina, E.S., Systemic inflammation and complications of “vascular” comorbidity in patients with COPD, Arkh. Vnutr. Med., 2015, no. 5, pp. 49–54.

    Google Scholar 

  20. Trofimov, V., Mironova, Zh., and Belash, V., Overlap syndrome: COPD-asthma cross-syndrome, Vrach, 2013, no. 2, pp. 20–21.

    Google Scholar 

  21. Baturin, V.A., Shchetinin, E.V., and Malykhin, F.T., Regional specifics of microbial landscape in outpatients with lower respiratory tract infections, Int. J. Risk Saf. Med., 2015, vol. 27, suppl. 1, pp. S61–S62. doi 10.3233/JRS-150691

    Article  PubMed  Google Scholar 

  22. Charlson, M.E., Pompei, P., Ales, K. L., and McKenzie, C.R., A new method of classifying prognostic comorbidity in longitudinal studies: development and validation, J. Chronic Dis., 1987, vol. 40, no. 5, pp. 373–383.

    Article  CAS  PubMed  Google Scholar 

  23. Tashkin, D., Celli, B., Decramer, M., et al., Bronchodilator responsiveness in patients with COPD, Eur. Res. J., 2008, vol. 31, no. 4, pp. 742–750.

    Article  CAS  Google Scholar 

  24. Zeki, A., Schivo, M., Chan, A., et al., The asthma-COPD overlap syndrome: a common clinical problem in the elderly, J. Allergy, 2011. doi 10.1155/2011/861926

    Google Scholar 

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Correspondence to F. T. Malykhin.

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Original Russian Text © F.T. Malykhin, 2017, published in Uspekhi Gerontologii, 2017, Vol. 30, No. 1, pp. 143–148.

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Malykhin, F.T. Indicators of comorbidity in chronic broncho-obstructive pathology. Adv Gerontol 7, 246–251 (2017). https://doi.org/10.1134/S2079057017030092

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