Abstract
The peptide–protein complex from bovine sclera was studied. It is shown that it contained a protein with a molecular weight of 66387 Da with the partial N-terminal amino acid sequence DTHKSEIAHRFKDLG-, which is homologous to the mature molecule of bovine serum albumin, and polypeptides with molecular weights of 1300–5080 Da. With a model of the organotypic cultivation of posterior eye tissues of the newt Pleurodeles waltl in vitro, it was shown that the effect of this peptide–protein complex in low doses increased the viability of scleral fibroblasts.
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Original Russian Text © E.V. Sidorskii, A.P. Il’ina, M.S. Krasnova, V.P. Yamskova, A.K. Buryak, I.A. Yamskov, 2018, published in Prikladnaya Biokhimiya i Mikrobiologiya, 2018, Vol. 54, No. 1, pp. 82–88.
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Sidorskii, E.V., Il’ina, A.P., Krasnova, M.S. et al. Physicochemical Properties and Biological Activity of the Peptide–Protein Complex from Bovine Scleral Tissue. Appl Biochem Microbiol 54, 83–88 (2018). https://doi.org/10.1134/S000368381801012X
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DOI: https://doi.org/10.1134/S000368381801012X