Skip to main content
Log in

Knowledge transfer initiative between molecular biologists and environmental researchers and regulators

  • Commentary
  • Subject Area 4.2: Science Communication and Information, Information Management
  • Published:
Environmental Science and Pollution Research - International Aims and scope Submit manuscript

Abstract

A Natural Environment Research Council (NERC) funded Knowledge Transfer (KT) workshop was held in the United Kingdom (UK) to identify the needs and opportunities in the application of molecular biology and ‘omics’ techniques to environmental monitoring and risk assessment. Attendees highlighted a lack of effective communication between end-users and researchers as well as difficulties with data interpretation as reasons behind the slow uptake of molecular biology and omics techniques. A number of promising areas in which new techniques could be implemented at a practical level in the very near future were identified, thereby raising the profile of these recent technologies and providing vital proof of concept work. Molecular taxonomy, bacterial source tracking and pre-screening of chemicals for potential toxicities were all viewed as areas in which omics and molecular techniques could have immediate value, with the aim of reducing cost, increasing efficiency and providing more comprehensive data of improved quality.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Ankley GT, Daston GP, Degitz SJ, Denslow ND, Hoke RA, Kennedy SW, Miracle AL, Perkins EJ, Snape J, Tillitt DE, Tyler CR, Versteeg D (2006): Toxicogenomics in Regulatory Ecotoxicology. Environ Sci Technol 40, 4055–4065

    Article  CAS  Google Scholar 

  • Centre for Evidence-Based Conservation. (2007): CEBC Systematic Reviews. Available from: 〈http://www.aebc.bham.ac.uk/systematicreviews.htm〉 (cited 27/03/07)

  • Côté IM, Gill JA, Gardner TA, Watkinson AR (2005): Measuring coral reef decline through meta-analyses. Phl Trans Royal Soc Biol Sci 360, 385–395

    Article  Google Scholar 

  • Ellinger-Ziegelbauer H, Stuart B, Wahle B, Bonann W, Ahr HJ (2005): Comparison of the expression profiles induced by genotoxic and nongenotoxic carcinogens in rat liver. Mutation Research 575, 61–84

    CAS  Google Scholar 

  • Hines A, Oladiran GS, Bignell JP, Stentiford GD, Viant MR (2007): Direct sampling of organisms from the field and knowledge of their phenotype: Key recommendations for environmental metabolomics. Environ Sci Technol 41, 3375–3381

    Article  CAS  Google Scholar 

  • Lindon JC, Keun HC, Ebbels TMD, Pearce JMT, Holmes E, Nicholson JK (2005): The Consortium for Metabonomic Toxicology (COMET): aims, activities and achievements. Pharmacogenomics 6, 691–699

    Article  CAS  Google Scholar 

  • Moggs JG, Tinwell H, Spurway T, Chang H.S, Pate I, Lim FL, Moore DJ, Soames A, Stuckey R, Currie R, Zhu T, Kimber I, Ashby J, Orphanides G (2004): Phenotypic anchoring of gene expression changes during estrogen-induced uterine growth. Environ. Health Perspect 112, 1589–606

    Article  CAS  Google Scholar 

  • Soetaert A, van der Ven K, Moens LN, Vandenbrouck T, van Remortel P, De Coen WM (2007): Daphnia magna and ecotoxicogenomics: Gene expression profiles of the anti-ecdysteroidal fungicide fenarimol using energy-, molting-and life stage-related cDNA libraries. Chemosphere 67, 60–71

    Article  CAS  Google Scholar 

  • Sutherland WJ, Armstrong-Brown S, Armsworth PR, Brereton T, Brickland J, Campbell CD, Chamberlain DE, Cooke AI, Dulvy NK, Dusic NR, Fitton M, Freckleton RP, Godfray HCJ, Grout N, Harvey HJ, Hedley C, Hopkins JJ, Kift NB, Kirby J, Kunin WE, MacDonald DW, Marker B, Naura M, Neale AR, Oliver T, Osborn D, Pullin AS, Shardlow MEA, Showler DA, Smith PL, Smithers RJ, Solandt J, Spencer J, Spray CJ, Thomas CD, Thompson J, Webb SE, Yalden DW, Watkinson AR (2006): The identification of 100 ecological questions of high policy relevance in the UK. J Applied Ecology 43, 617–627

    Article  Google Scholar 

  • Viant MR, Bundy JG, Pincetich CA, de Ropp JS, Tjeerdema RS (2005): NMR-derived developmental metabolic trajectories: An approach for visualizing the toxic actions of trichloroethylene during embryogenesis. Metabolomics 1, 149–158

    Article  CAS  Google Scholar 

  • Viant MR, Pincetich CA, Hinton DE, Tjeerdema RS (2006): Toxic actions of dinoseb in medaka (Oryzias latipes) embryos as determined by in vivo 31P NMR, HPLC-UV and 1H NMR metabolomics. Aquatic Toxicology 76, 329–342

    Article  CAS  Google Scholar 

  • Waring JF, Jolly RA, Ciurlionis R, Lum PY, Praestgaard JT, Morfitt DC, Buratto B, Roberts C, Schadt E, Ulrich RG (2001): Clustering of hepatotoxins based on mechanism of toxicity using gene expression profiles. Toxicol Applied Pharmacol 175, 28–42

    Article  CAS  Google Scholar 

  • Williams TD, Diab AM, George SG, Godfrey RE, Sabine V, Conesa A, Minchin SD, Watts PC, Chipman JK, (2006): Development of the GENIPOL European flounder (Platichthys flesus) microarray and determination of temporal transcriptional responses to cadmium at low dose. Environ Sci Technol 40, 6479–88

    Article  CAS  Google Scholar 

  • OECD (2005): Report of the OECD/IPCS Workshop on Toxicogenomics. OECD Environmental Health and Safety Publications, Series on Testing and Assessment No. 50, April 2005 〈http://appli1.oecd.org/olis/2005doc.nsf/43bb6130e5e86e5fc12569fa005d004c/d49a5f7fdfa04f97c1256ff200379c99/$FILE/JT00183336.PDF

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to James K. Chipman.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Blunt, R.E., Walsh, K.A., Ashton, D.K. et al. Knowledge transfer initiative between molecular biologists and environmental researchers and regulators. Env Sci Poll Res Int 14, 293–296 (2007). https://doi.org/10.1065/espr2007.06.431

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1065/espr2007.06.431

Keywords

Navigation