Abstract
In the course of epizootological research on Lyme borreliosis in domestic and farm animals, the serological evidence for the occurrence of this zoonosis in cattle was screened. An ELISA showed that 25.2% of cattle from seven geographical areas in Slovakia were positive for anti-Borrelia IgG antibodies. In particular localities, the seroprevalence ranged from 0.6% to 34.3%. Of 33 cases with clinical signs, 20 ELISA-positive samples were also confirmed in Western blots. The most frequent clinical signs were lameness and swollen joints, but most of the cases were asymptomatic. The occurrence of Borrelia burgdorferi antibodies and suspected clinical signs in cattle of Slovak regions indicates that veterinarians should pay attention to this disease in their clinical practice and include it within the differential diagnosis.
Similar content being viewed by others
REFERENCES
Appel, M.J.G., Allan, S., Jacobson, R.H., Lauderdale, T.L., Chang, Y.F., Shin, S.J., Thomford, J.W., Todhunter, R.J. and Summers, B.A., 1993. Experimental Lyme disease in dogs produces arthritis and persistent infection. Journal of Infectious Diseases, 167, 651-664
Blowey, R.W., Carter, S.D., White, A.G. and Barne, A., 1994. Borrelia burgdorferi infection in UK cattle: a possible association with digital dermatitis. The Veterinary Record, 135, 577-578
Borko, Č., 2000. Humoral immune response to bacteria Borrelia burgdorferi s.1 in cattle after natural and experimental exposure. Veterinarske novice, 26, 120-123
Burgess, E.C., 1986. Experimental inoculation of dogs with Borrelia burgdorferi. Zentralblatt für Bakteriologie und Hygiene (A), 263, 49-54
Burgess, E.C., 1988. Borrelia burgdorferi infection in Wisconsin horses and cows. Annals of the New York Academy of Sciences, 539, 235-243
Burgess, E.C., Gentron-Fitzpatrick, A. and Wright, W.O., 1987. Arthritis and systemic disease caused by Borrelia burgdorferi infection in cows. Journal of the American Veterinary Medical Association, 191, 1468-1470
Burgess, E.C., Wachal, M.D. and Cleven, T.D., 1993. Borrelia burgdorferi infection in dairy cows, rodents and birds from four Wisconsin dairy farms. The Veterinary Microbiology, 35, 61-77
Buschmich, S.L., 1994. Lyme borreliosis in domestic animals. Journal of Spirochetal and Tick-Borne Diseases, 1, 24-28
Buschmich, S.L. and Post, J.E., 1992. Lyme borreliosis in dairy cattle. Vth International Conference on Lyme Borreliosis, Arlington, VA. Abstract, 172
Cabannes, A., Hernandez, J.C., Lucchese, F., Appriou, M. and Tribouley-Duret, J., 1997. Epidemiology of Lyme disease in cattle and sheep in Gironde (France). Medicine et Maladies Infectieuses, 27, 878-883
Cutler, S.J., Wright, D.J.M. and Luckhurst, V.H., 1993. Simplified method for the interpretation of immunoblots for Lyme borreliosis. FESM Immunology and Medical Microbiology, 33, 1473-1478
Demirkan, I., Walker, R.I., Murray, R.D., Blowey, R.W. and Carter, S.D., 1999. Serological evidence for spirochaetal infection associated with digital dermatitis in dairy cattle. The Veterinary Journal, 157, 69-77
Demirkan, I., Murray, R.D. and Carter, S.D., 2000. Skin diseases of the bovine digit associated with lameness. Veterinary Bulletin, 70, 149-171
Drgoňová, M. and Řeháček, J., 1995. Prevalence of Lyme Borrelia in ticks in Bratislava, Slovak Republic. Central European Journal of Public Health, 3, 134-137
Fraser, C.M., Casjens, S. and Huang, W.M., 1997. Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi. Nature, 390, 580-586
Greene, R.T., Levine, J.F., Breitschwerdt, E.B., Walker, R.L., Berkhoff, H.A., Cullen, J. and Nicholson, W.L., 1988. Clinical and serologic evaluations of induced Borrelia burgdorferi infection in dogs. American Journal of Veterinary Research, 49, 752-757
Hauser, U., Lehnert, G., Lobentanzer, R. and Wilske, B., 1997. Interpretation criteria for standardized Western blots for three species of Borrelia burgdorferi sensu lato. Journal of Clinical Microbiology, 35, 1433-1444
Hovmark, A., Äsbrink, E., Schwan, O., Hederstedt, B. and Christensson, D., 1986. Antibodies to Borrelia spirochetes in sera from Swedish cattle and sheep. Acta Veterinaria Scandinavica, 27, 479-485
Ji, B. and Collins, M.T., 1994. Seroepidemiologic survey of Borrelia burgdorferi exposure of dairy cattle in Wisconsin. American Journal of Veterinary Research, 55, 1228-1231
Kmety, E. and Bakoss, P., 1978. To the issue of the selection of antigens for the microscopic agglutination reaction in leptospirosis. Československá Epidemiologie, 27, 247-252 (in Slovak)
Kmety, E., Řeháček, J. and Vyrosteková, V., 1986. Investigations of ticks for the presence of Borrelia in Czechoslovakia. Zentralblatt für Bakteriologie und Hygiene (A), 263, 468-470
Kmety, E., Řeháček, J. and Vyrosteková, V., Kocianová, E. and Guričová, D., 1990. Studies on infestation of Borrelia burgdorferi and Franciscella tularensis with ticks in Slovakia. Bratislavské Lekárske Listy, 91, 251-266 (in Slovak)
Koniarova, I., Orsag, A. and Ledecký, V., 1993. The ratio anaerobic bacteria on the dermatitis digitalis et interdigitalis in cattle. Veterinary Medicine (Czech), 38, 589-596
Laemli, U.K., 1970. Cleveage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 227, 680-685
McKenna, P., Clement, J., Van Dijck, D., Lauwerys, M., Carey, D., Van den Bogaard, T. and Bigaignon, G., 1995. Canine Lyme disease in Belgium. The Veterinary Record, 136, 244-247
Magnarelli, L.A. and Anderson, J.F., 1989. Class-specific and polyvalent enzyme-linked immunosorbent assay for detection of antibodies in equids. Journal of the American Veterinary Medical Association, 195, 1365-1368
Marcus, L.C., Patterson, M.M., Eilfillan, R.E. and Urband, P.H., 1985. Antibodies to Borrelia burgdorferi in New England horses: serologic survey. American Journal of Veterinary Research, 46, 2570
Norman, G.L., Antig, J.M., Bigaignon, G. and Hogrefe, W.R., 1996. Serodiagnosis of Lyme borreliosis by Borrelia burgdorferi sensu stricto, B. garinii and B. afzelii western blots (immunoblots). Journal of Clinical Microbiology, 34, 1732-1738
Parker, J.L. and White, K.K., 1992. Lyme borreliosis in cattle and horses: a review of the literature. Cornell Veterinarian, 82, 253-274
Pet'ko, B., Štefančíková, A., Tresová, G., Peterková, J., Škardová, I., Prokopčáková, H. and Čisláková, L., 1996. Common tick (Ixodes ricinus) as a source of infection of human and dogs with the agent of Lyme borreliosis in Slovakia. Slovenský Veterinársky Časopis, 21, 313-318 (in Slovak)
Post, J.E., 1990. Lyme disease in large animals. New Jersey Medicine, 87, 575-577
Post, J.E., Shaw, E.E. and Wright, S., 1986. Suspected borreliosis in cattle. Annals of the New York Academy of Sciences, 539, 488
Reisenauer, R., 1970. Mathematico-statistical Methods and Their Applications in Technology, SNTL, Prague (in Czech)
Řeháček, J., Kmety, E., Kociánová, E., Vyrosteková, V., Sekeyová, Z. and Vavreková, M., 1991. Prevalence of Borrelia burgdorferi in ticks in Slovakia. In: Dusbásek, F. and Bukva, V. (eds), Modern Acarology. (Academia Prague and SPB Academic Publishing, The Hague), 2, 61-65
Stanek, G., Jurkowitsch, B. and Kochl, C., 1990. Reactivity of European and American isolates of Borrelia burgdorferi with different monoclonal antibodies by means of a microimmunoblot technique. Zentralblatt für Bakteriologie, 272, 426-436
Štefančíková, A., Škardová, I., Pet'ko, B., Janovská, D. and Cyprichová, V., 1996. Antibodies IgG to Borrelia burgdorferi in dogs from Košice region. Veterinary Medicine Czech, 41, 83-86 (in Slovak)
Štefančíková, A., Štěpánová, G., Pet'ko, B., Nadzamová, D., Szestáková, E., Škardová, I. and Leinstein, R., 2000. Prevalence of antibodies to Borrelia burgdorferi in horses of east Slovakia. Veterinary Medicine Czech, 45, 227-231
Towbin, H., Staehlin, T. and Gordon, J., 1979. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets. Procedure and some applications. Proceedings of the National Academy of Sciences of the USA, 76, 4350-4354
Tresová, G., Mateička, T., Pet'ko, B. and Kozárová, D., 1997. Preliminary identification of Borrelia burgdorferi isolates from ticks Ixodes ricinus in eastern Slovakia. Epidemiology, Microbiology and Immunology, 46, 36-38 (in Slovak)
Tuomi, J., Rentamäki, L.K. and Tanskanen, R., 1998. Experimental infection of cattle with several Borrelia burgdorferi sensu lato strains; immunological heterogeneity of strains as revealed in serological tests. Veterinary Microbiology, 60, 27-43
Walker, R.L., Read, D.H., Loretz, K.J. and Nordhausen, R.W., 1995. Spirochetes isolated from dairy cattle with papilomatous digital dermatitis and interdigital dermatitis. Veterinary Microbiology, 47, 343-355
Weaver, A.D., 1997. Joint conditions. In: P.R. Greenough (ed.), Lameness in Cattle, 3rd edn, (W.B. Saunders, Philadelphia), 162-180
Wells, S.J., Trent, A.M., Robinson, R.A., Knutson, K.S. and Bey, R.F., 1993. Association between clinical lameness and Borrelia burgdorferi antibody in dairy cows. American Journal of Veterinary Research, 54, 398-405
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Štefančíková, A., Štěpánová, G., Derdáková, M. et al. Serological Evidence for Borrelia burgdorferi Infection Associated with Clinical Signs in Dairy Cattle in Slovakia. Vet Res Commun 26, 601–611 (2002). https://doi.org/10.1023/A:1020912618950
Issue Date:
DOI: https://doi.org/10.1023/A:1020912618950