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The diffusion-tensor imaging reveals alterations in water diffusion parameters in acute pediatric concussion

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Abstract

Wide-spread visualization methods which are computed tomography (CT) and magnetic resonance imaging (MRI) are not sensitive to mild traumatic brain injury (mTBI). However, mTBI may cause changes of cerebral microstructure that could be found using diffusion-tensor imaging. The aim of this study is to reveal the impact of acute mTBI (no more than 3 days after trauma) on diffusion parameters in corpus callosum, corticospinal tract, and thalamus in children (aged 14–18). Fractional anisotropy (FA) and apparent diffusion coefficient (ADC) were analyzed. Significant increase in FA and decrease in ADC were observed in thalamus. The trend to an increase in FA is observed in corpus callosum.

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Authors and Affiliations

  1. Clinical and Research Institute of Emergency Pediatric Surgery and Trauma, 22, Bol’shaya Polyanka St., Moscow, 119180, Russia

    O. R. Vasiukova, M. I. Akhlebinina, A. V. Manzhurtsev, M. V. Ublinskiy, A. N. Yakovlev, T. A. Akhadov & N. A. Semenova

  2. N.M. Emanuel Institute of Biochemical Physics of the Russian Academy of Sciences, 4, Kosygina St., Moscow, 119334, Russia

    A. V. Manzhurtsev, P. E. Menshchikov, M. V. Ublinskiy, A. N. Yakovlev & N. A. Semenova

  3. N.N. Semenov Institute of Chemical Physics of the Russian Academy of Sciences, 4, Kosygina St., Moscow, 119334, Russia

    A. N. Yakovlev & N. A. Semenova

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  1. O. R. Vasiukova
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  2. M. I. Akhlebinina
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  3. A. V. Manzhurtsev
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  4. P. E. Menshchikov
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  5. M. V. Ublinskiy
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  6. A. N. Yakovlev
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  7. T. A. Akhadov
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  8. N. A. Semenova
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Correspondence to A. V. Manzhurtsev.

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Vasiukova, O.R., Akhlebinina, M.I., Manzhurtsev, A.V. et al. The diffusion-tensor imaging reveals alterations in water diffusion parameters in acute pediatric concussion. Acta Neurol Belg 121, 1463–1468 (2021). https://doi.org/10.1007/s13760-020-01347-w

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  • DOI: https://doi.org/10.1007/s13760-020-01347-w

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