Skip to main content

Advertisement

Log in

Idiopathic limbic encephalitis associated with antibodies to glutamic acid decarboxylase

  • Letter to the Editor
  • Published:
Acta Neurologica Belgica Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Leypoldt F, Wandinger KP, Bien CG, Dalmau J (2013) Autoimmune encephalitis. Eur Neurol Rev 8:31–37

    Google Scholar 

  2. Malter MP, Helmstaedter C, Urbach H, Vincent A, Bien CG (2010) Antibodies to glutamic acid decarboxylase define a form of limbic encephalitis. Ann Neurol 67:470–478

    Article  PubMed  Google Scholar 

  3. Saiz A, Blanco Y, Sabater L, González F, Bataller L, Casamitjana R, Ramió-Torrentà L, Graus F (2008) Spectrum of neurological syndromes associated with glutamic acid decarboxylase antibodies: diagnostic clues for this association. Brain 131:2553–2563

    Article  PubMed  Google Scholar 

  4. Chang T, Alexopoulos H, McMenamin M, Carvajal-González A, Alexander SK, Deacon R, Erdelyi F, Gabor S, Lang B, Blaes F, Brown P, Vincent A (2013) Neuronal surface and glutamic acid decarboxylase autoantibodies in Nonparaneoplastic stiff person syndrome. JAMA Neurol 70:1140–1149

    Article  PubMed  Google Scholar 

  5. Castillo P, Woodruff B, Caselli R, Vernino S, Lucchhinetti C, Swanson J, Noseworthy J et al (2006) Steroid-responsive encephalopathy associated with autoimmune thyroiditis. Arch Neurol 63:197–202

    Article  PubMed  Google Scholar 

  6. Manto MU, Laute MA, Aguera M, Rogemond V, Pandolfo M, Honnorat J (2007) Effects of anti-glutamic acid decarboxylase antibodies associated with neurological diseases. Ann Neurol 61:544–551

    Article  CAS  PubMed  Google Scholar 

  7. Lancaster E, Lai M, Peng X et al (2010) Antibodies to the GABA(B) receptor in limbic encephalitis with seizures: case series and characterization of the antigen. Lancet Neurol 9:67–76

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  8. Höftberger R, Titulaer MJ, Sabater L, Dome B, Rozsas A et al (2013) Encephalitis and GABAb receptor antibodies. Novel findings in a new case series of 20 patients. Neurology 81:1500–1506

    Article  PubMed Central  PubMed  Google Scholar 

  9. Petit-Pedrol M, Armangue T, Peng X, Bataller L, Cellucci T et al (2014) Encephalitis with refractory seizures, status epilepticus, and antibodies to the GABAa receptor: a case series, characterisation of the antigen, and analysis of the effects of antibodies. Lancet Neurol 13:276–286

    Article  CAS  PubMed  Google Scholar 

  10. Burton AR, Baquet Z, Eisenbarth GS et al (2010) Central nervous system destruction mediated by glutamic acid decarboxylase-specific CD4+ T cells. J Immunol 184:4863–4870

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  11. Titulaer MJ, McCracken L, Gabilando I, Armangué T, Glaser C et al (2013) Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: an observational cohort study. Lancet Neurol 12:157–165

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  12. Frisch C, Malter MP, Elger CE, Helmstaedter C (2013) Neuropsychological course of voltage-gated potassium channel and glutamic acid decarboxylase antibody related limbic encephalitis. Eur J Neurol 20:1297–1304

    Article  CAS  PubMed  Google Scholar 

Download references

Conflict of interest

None.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Christian J. M. Sindic.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Millet, C., van Pesch, V. & Sindic, C.J.M. Idiopathic limbic encephalitis associated with antibodies to glutamic acid decarboxylase. Acta Neurol Belg 115, 165–167 (2015). https://doi.org/10.1007/s13760-014-0332-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13760-014-0332-9

Keywords

Navigation