Skip to main content

Advertisement

SpringerLink
Log in

A case of pulmonary artery intimal sarcoma successfully treated using concurrent chemoradiotherapy and subsequent chemotherapy

  • Case report
  • Published:
International Cancer Conference Journal Aims and scope Submit manuscript

Abstract

Pulmonary artery intimal sarcoma (PAIS) is a rare malignancy with an extremely poor prognosis. A 43-year-old man visited our hospital with shortness of breath and suddenly experienced cardiopulmonary arrest before he could be examined. After prompt resuscitation, we diagnosed PAIS, but the patient refused to undergo surgery because of the high perioperative mortality risk. Thus, the patient was treated using concurrent chemoradiotherapy with weekly paclitaxel therapy, as well as subsequent chemotherapy. The patient continued chemotherapy for 36 months until he elected to discontinue treatment. To the best of our knowledge, this is the first case of PAIS, which is difficult to resect, that was successfully treated using concurrent chemoradiotherapy and subsequent chemotherapy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

References

  1. Mandelstamm M (1923) Uber primare Neubildungen des Herzens. Virchows Arch Pathol Anat 245:43–45

    Article  Google Scholar 

  2. Bandyopadhyay D, Panchabhai TS, Bajaj NS et al (2016) Primary pulmonary artery sarcoma: a close associate of pulmonary embolism- 20-year observational analysis. J Thorac Dis 8:2592–2601

    Article  PubMed Central  PubMed  Google Scholar 

  3. Wong HH, Gounaris I, McCormack A et al (2015) Presentation and management of pulmonary artery sarcoma. Clin Waarcoma Res 5:3

    Article  CAS  Google Scholar 

  4. Mussot S, Ghigna MR, Mercier O et al (2013) Retrospective institutional study of 31 patients treated for pulmonary artery sarcoma. Eur J Cardiothorac Surg 43:787–793

    Article  PubMed  Google Scholar 

  5. Parish JM, Rosenow EC 3rd, Swensen SJ et al (1996) Pulmonary artery sarcoma. Clinical features. Chest 110:1480–1488

    Article  CAS  PubMed  Google Scholar 

  6. Kurger I, Borowski A, Horst M et al (1990) Symptoms, diagnosis, and therapy of primary sarcoma of the pulmonary artery. Thorac Cardiovasc Surg 38:91–95

    Article  Google Scholar 

  7. Travis WD, Brambilla E, Burke AP et al (2015) WHO classification of tumours of lung, pleura, thymus & heart. 4th edn. IARC Press, Lyon, pp 28–129

    Google Scholar 

  8. Jiang S, Li J, Zeng Q, Liang J (2017) Pulmonary artery intimal sarcoma misdiagnosed as pulmonary embolism: a case report. Oncol Lett 13:2713–2716

    Article  PubMed Central  PubMed  Google Scholar 

  9. Lee Y, Kim HJ, Yoon H et al (2016) Clinical characteristics and treatment outcomes of primary pulmonary artery sarcoma in Korea. J Korean Med Sci 31:1755–1760

    Article  PubMed Central  PubMed  Google Scholar 

  10. Ote EL, Oriuchi N, Miyashita G et al (2011) Pulmonary artery intimal sarcoma: the role of 18F-fluorodeoxyglucose positron emission tomography in monitoring response to treatment. Jpn J Radiol 29:279–282

    Article  PubMed  Google Scholar 

  11. Yeung DF, Johnston A, Simmons C et al (2018) Multimodality imaging of a pulmonary artery sarcoma. Echocardiography 35:123–125

    Article  PubMed  Google Scholar 

  12. Hmelik S, Dobrenic M, Huic D (2018) F-18 FDG PET/CT in pulmonary artery sarcoma: clinical vignette. Nucl Med Rev Cent East Eur 21:48–49

    Article  PubMed  Google Scholar 

  13. Blackman SH, Rice DC, Correa AM et al (2009) Management of primary pulmonary artery sarcomas. Ann Thorac Surg 87:977–984

    Article  Google Scholar 

  14. Yin K, Zhanu Z, Luo R et al (2018) Clinical features and surgical outcomes of pulmonary artery sarcoma. J Thorac Cardiovasc Surg 155:1109–1115

    Article  PubMed  Google Scholar 

  15. Penel N, Bui BN, Bay JO et al (2008) Phase II trial of weekly paclitaxel for unresectable angiosarcoma: the ANGIOTAX study. J Clin Oncol 26:5269–5274

    Article  CAS  Google Scholar 

  16. National Comprehensive Cancer Network (2018) National Comprehensive Cancer Network Guidelines: Soft tissue sarcoma version 1.2018. https://www.nccn.org/professionals/physician_gls/pdf/sarcoma.pdf. Accessed Mar 2018

  17. Fujisawa Y, Yoshino K, Kadono T et al (2014) Chemoradiotherapy with taxane is superior to conventional surgery and radiotherapy in the management of cutaneous angiosarcoma: a multicentre, retrospective study. Br J Dermatol 171:1493–1500

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Clinical Oncology, Fukuyama City Hospital, Hiroshima, Japan

    Terumi Aso, Masako Terao & Hisashi Endo

  2. Center for Clinical Oncology, Okayama University Hospital, Okayama, Japan

    Masahiro Tabata

Authors
  1. Terumi Aso
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Masako Terao
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Hisashi Endo
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Masahiro Tabata
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Terumi Aso.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Research involving Human Participants

For this type of study, formal consent is not required.

Informed consent

Informed consent was obtained from all individual participants included in the study.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Aso, T., Terao, M., Endo, H. et al. A case of pulmonary artery intimal sarcoma successfully treated using concurrent chemoradiotherapy and subsequent chemotherapy. Int Canc Conf J 8, 71–76 (2019). https://doi.org/10.1007/s13691-018-00356-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13691-018-00356-0

Keywords

Search

Navigation