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Echocardiographic assessment of long-term hemodynamic characteristics of mechanical mitral valve prostheses with different mitral valvular diseases

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Abstract

Mitral stenosis (MS) and mitral insufficiency (MI) have different pre-operative hemodynamic characteristics. However, it is unclear if there are differences in long-term echocardiographic characteristics of MS and MI patients after mechanical mitral valve replacement. This study is to compare long-term echocardiographic results of mechanical mitral valve prostheses between MS and MI patients. From January 2003 to January 2009, a total of 199 consecutive patients were recruited in this study. Patients were classified as group MS (n = 123) and MI (n = 76) according to the manifestation of mitral valvular disease. The mean age for patients was 50.1 ± 10.5 years and follow-up time was 7.2 ± 2.0 years. The MS after operation were more likely to experience atrial fibrillation (p = 0.002). The New York Heart Association (NYHA) class in MI showed a greater improvement (p = 0.006) than in MS. The left ventricular end-diastolic dimension (LVEDD) (p = 0.010) and stroke volume (SV) (p = 0.000) in MI were still larger than that in MS patients. These differences did not disappear with time after operation. The long-term echocardiographic results of mechanical mitral valve prostheses between MS and MI patients are significantly different. Over a long-term follow up, MI patients still have a larger LVEDD and SV than MS, and associated with a greater improvement of NYHA class.

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Correspondence to Xijun Xiao.

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The authors declare that they have no conflicts of interest.

Ethical approval

This retrospective study followed the tenets of Declaration of Helsinki and was approved by the ethics review board of West China Hospital, Sichuan University. The written informed consent was obtained from all patients at the time of admission, and the information of patients was anonymized and de-identified prior to analysis.

Additional information

Xiliang Zhu and Qian Li have contributed equally to this work.

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Zhu, X., Li, Q., Tang, H. et al. Echocardiographic assessment of long-term hemodynamic characteristics of mechanical mitral valve prostheses with different mitral valvular diseases. Australas Phys Eng Sci Med 40, 259–266 (2017). https://doi.org/10.1007/s13246-016-0521-3

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  • DOI: https://doi.org/10.1007/s13246-016-0521-3

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